An analysis of the cases encountered over the last 5 years revealed a high frequency of gastric cancers located in the upper pole area of the stomach. These represented 23% of all gastric cancers. The low number of cases with this localization that could benefit from gastric resection (38,7%), in contrast with distal locations (65,4%) suggest either late detection or high invading potential of these cancers. Oeso-gastric resection - the only efficient curative or palliative treatment - was adapted according to site and extension of the tumour in both organs. In 6 cases partial resection of the thoracic oesophagus was necessary, and in another 4 cases total gastrectomy was performed. In 8 patients upper polar resection - including the oesophagus - was satisfactory from the oncologic viewpoint, and was well-tolerated by the patients.

Adult↗

PubMedDate not supplied

[Islet cell tumors of the pancreas].

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Adenoma, Islet Cell↗

PubMedDate not supplied

Gastrin (G) cells in gastric carcinoma.

The behaviour of gastrin cells in the antral mucosa in gastric carcinoma was electron microscopically investigated using specimens of surgically resected stomachs. The results pointed out that in gastric carcinoma there takes place a change of the types of G cell population in the antral mucosa. In this condition, a significant fact was the predominance of intestinal G cells, known to store mainly G 34.

Adenocarcinoma↗

PubMedDate not supplied

Gastrin cells in stomach and duodenal ulcers.

By means of cytochemical and electron microscopy methods, the behavior of gastrin cells in ulcers of the stomach and duodenum were investigated. The study was performed on specimens of surgical resection from stomach and duodenal ulcers with gastric normacidity. The results point out a significant decrease of gastrin cells in stomach ulcers in comparison with the duodenal ones. These findings in stomach ulcers were attributed to the high intensity of gastritis lesions, histopathologically evidenced. Electron microscopy revealed that gastrin cells were loaded with secretion granules presenting suggestive images of synthesis activity.

Duodenal Ulcer↗

PubMedDate not supplied

Enterochromaffin cells (EC) of the antropyloric mucosa in gastric and duodenal ulcers.

Enterochromaffin cells (EC) within the antropyloric mucosa in resected stomach from patients with gastric and duodenal ulcers were investigated by means of cytochemical and electron microscopy. The proliferation of antral EC cells was pointed out; among them EC cells of gastric and intestinal type were identified. The proliferation of antral EC cells seems to be related to the intensity of chronic gastritis.

Chromaffin System↗

PubMedDate not supplied