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Biomedical subjects

C Didilescu

Publications and source records attributed to C Didilescu.

At least 73 records · Page 4Linked to original sources
PubMedDate not supplied

[Post-tuberculosis syndromes appearing in cases undergoing initial chemotherapy].

The study of frequency and of the nature of post-tuberculous syndromes in a group including 1351 patients with pulmonary tuberculosis at their first treatment, investigated between 1974 and 1977, has demonstrated that in the present stage of initial chemotherapy with standardized drug regimens, the post-tuberculous syndromes are decreasing in most of the cases, developing in those of the patients that presented with advanced froms of the disease at the start of the the therapy (2,8% in our study). At the same time one should note the prevalence of patients that have benefited from initial courses of chemotherapy with classical and relay drugs, such patients usually having less severe anatomic and radiologic lesions. The study of types of post-tuberculous syndromes has revealed the increased frequency of the bronchitic syndrome.

Antitubercular Agents↗
PubMedDate not supplied

[Notes on 2 cases of pneumonia caused by Klebsiella pneumoniae].

In two cases of bacterial pneumonia occurring in adults which were due to Klebsiella pneumoniae germs. The evolution became chronic with extensive invasion of the pulmonary tissues and destruction of the parenchyma. There was also multiple resistance of the germs to antibiotics as evidenced by sensitivity tests. The severe pleural complications have determined serious difficulties in the performance of the treatment. Confronted with such a condition the only therapeutical attitude consisted in testing the known antibiotics with efficiency in Klebsiella infections.

Aged↗
PubMedDate not supplied

[Economic and social implications of post-tuberculosis syndromes].

The fact that 30.5% of patients with post-tuberculous syndromes belonging to a category of active population have been pensioned off for health reasons is a demonstration that these syndromes may play a significant role in determining the incapacity for work. The practical conclusion is that the prophylaxis of post-tuberculous syndromes--early diagnosis, chemotherapy with new drugs, and kinesitherapy--in all cases of tuberculosis at their first treatment may determine a deceased incidence of these syndromes. The reduction of the percentage of post-tuberculous syndromes recorded for 100 cases of tuberculosis treated with modern therapeutic regimens will result in a collective benefit consisting in a lower pressure on the general and specialized sanitary network with regard to the number of procedures provided. The health network potentialities could this be used for the solving of other problems of public health. At the same time by reducing the percentage of post-tuberculous syndromes, important funds can be spared, which are used for treatment, sick-leave pay, and invalidity pensions. The continuous improvement of the organizational frame of health protection in our country should consider also the official regulatory of the medico-social status of patients with post-tuberculous syndromes.

Disability Evaluation↗
PubMedDate not supplied

Contributions to the study of the etiology of serofibrinous pleurisy in Romania, under the present epidemiological conditions. Evaluation of the etiological role of viruses.

A number of 56 serofibrinous pleurisy cases were subjected to several usual diagnostic tests, as well as to virological investigations. Significant rises in serum antibody titers to different viruses were recorded in 25 cases; the presence of virus antigens in cells from the pleural fluid could be visualized by immunofluorescence in 11 patients. In many cases there was evidence suggesting multiple viral infection. The contribution of various investigation methods to differential diagnosis is discussed and the etiological patterns specific to different territories are outlined.

Antibodies, Viral↗
PubMedDate not supplied

[The prevalence of tuberculous infection in 6- and 14-year-olds in 1990-1991].

Tb infection prevalence and incidence are considered as the most relevant epidemiological indices which characterizes the endemic disease in a population. The study tried to establish the level of Tb infection prevalence in the age groups "6-7" and "14-15", based on the information included in the card-index for BCG pre- vaccination in the above groups, in 11 districts of Romania and the city of Bucharest. To calculate the Tb prevalence results from the BCG tests in 24,175 pupils aged 6 and 14, the persons with reactions of 10-19 mm Palmer type I-II, and reactions > or = 20 mm regardless the Palmer type were considered as infected. In 1990, infection prevalence was of 2.13% and 6.73% in pupils aged 6 and 14, respectively. The study was not intended to establish the average level of Tb infection prevalence for the whole country since it would have required adequate samples of population and working teams of the same technical level as regards skin testing and its interpretation. The obtained data allowed the calculation of the average annual rate of infection for "age-group 0-6" within the study group (0.36%). It is estimated that infection prevalence evolution can be followed up at district level, by processing the data of the card-index for pre-vaccinal tests in the pupils of the I-st and VIII-th forms.

Adolescent↗
PubMedDate not supplied

[Tuberculosis in the elderly: sociomedical aspects].

A study on a group of 100 tb patients aged over 60 years registered between 1987-1991 in the district 4 of Bucharest has been carried out aiming at the evaluation of medical and social aspects. In order to increase the relevance of the obtained data, these were compared with a group of young tb patients aged 20-39 years, in the same territory and period of time. The results show: the case-finding predominantly passive, extrarespiratory forms in 25%, high contamination risk (63% acid fast bacilli eliminators on microscopy) non-compliance to treatment in 1/5 of cases. These aspects could be explained by psychic particular features in aged persons, associated diseases a.s.o., leading to treatment failures. The analysis of social and epidemiological aspects of tb in aged subjects evidences some lack of good results in this important public health problem of people.

Adult↗
PubMedDate not supplied

[Tuberculosis in the city of Bucharest in 1989-1993].

The global incidence of tuberculosis increased during the last 5 years in the city of Bucharest by 37.8%, from 84.2%000 in 1989 to 116.0%000 in 1993. The risk of disease was permanently higher in the rural area of the Ilfov Agricultural Sector (148.5%000 in 1993). During 1993 almost 55% of new cases of pulmonary tuberculosis registered in the city of Bucharest presented advanced lesions on case-finding; 71% of these cases were tb bacilli eliminators. In the epidemiological conditions induced by a marked increase of contamination sources (periodic prevalence of tb bacilli eliminators reached 111.6%000 in 1993) the disease risk in children increased as well in Bucharest from 19.6%000 in 1989 to 38.3%000 in 1993. Tuberculosis control in Bucharest benefits from a rather complex material basis which should be improved according to the present day epidemiological conditions.

Adolescent↗
PubMedDate not supplied

[An evaluation of the possibilities for a paraclinical study in outpatient pneumophthisiology care and proposals for its improvement].

An attempt was made to make an estimation of equipment and accessibility of pneumophthisiology ambulatory units for diagnosis and treatment of patients newly discovered and the already registered ones. A number of 172 (97% of total number) pneumophthisiology units have been taken into the study showing a certain progress regarding the lb diagnosis. As for other chronic lung diseases, the specific equipment is not available in all units: 73 have not spirometer, bronchoscopy is performed in other places, a.s.o. The situation requires urgent providing the pneumophthisiology network units with new techniques equipment for diagnosis and replacing the present one which is outdated and worn-out.

Ambulatory Care↗