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Biomedical subjects

C Deby

Publications and source records attributed to C Deby.

At least 109 records · Page 6Linked to original sources

[Relationship between lipemia and sensitivity to arachidonic acid in rabbits].

The hypotensive effect of arachidonic acid in the rabbit increases simultaneously with the fall of the plasmatic unesterified fatty acids (NEFA), after treatment with nicotinic acid or heparin. In the case of nicotinic acid sensitization, which occurs in 10 minutes, the fall of NEFA occurs immediately. The sensitization by heparin appears only after 40 minutes following the injection; during this latency, the NEFA are enhanced; after the fall of NEFA, the rabbit becomes more sensitive to arachidonic acid. Mechanisms of heparinic sensitization are discussed.

Animals↗

[Release of prostaglandins and their precursors by bradykinin].

Bradykinin induces a release of unsaturated fatty acids and of prostaglandins from the perfused rat lung. This release is inhibited by chloroquine, a phospholipase A inhibitor. Histamine has no stimulating effect on fatty acids production. It is suggested that prostaglandins release induced by bradykinin might depend on a phospholipase activation.

Animals↗