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Biomedical subjects

C Daniil

Publications and source records attributed to C Daniil.

At least 19 recordsLinked to original sources

[Splenic artery embolization in hematologic diseases in children].

In the past four years or so splenectomy used in children with hematological defects, who showed hypersplenism has been replaced with partial arterial splenic embolization (Pase), in general, 2/3 of the lower spleen were embolized. Pase was performed after the selective catheterization of the splenic artery up to the hilum with local anesthesia. As an embolizing agent, with the first 2 patients a suspension of Gelaspon microparticles and absolute alcohol (90 degrees) was used, and with the others (7 patients with 9 embolizations) only absolute alcohol. The Pase indication was: congenital hemolytic anemia in 5 cases; thrombocytopenia in 3 cases (5 pase); portal hypertension by extra-hepatic blockage with secondary hypersplenism in one case where the endoscopic sclerosis of the esophageal varices had been done first, followed by Pase after weeks. The evolution after Pase was simple in 6 patients: fever, pain in the left hypochondrium, and moderate ileus for 2-3 days. In 3 cases the evolution was both complicated and difficult excessive Pase in the first 2 patients, that practically resulted in total splenectomy, and, in the other one, the growth of a big subcapsular hematoma with effusion that had to be eliminated through transparietal drainage, under echographic control and operated secondary for peritonitis. Hematologically, in all cases but one (1 failure) hypersplenism remission was obtained and the results are the same 1-3 years after Pase. Partial arterial splenic embolization can very well replace splenectomy in hematological defects manifested as hypersplenism. The use of absolute alcohol (90 degrees) as an excellent embolization agent has not been reported so far in children.

Adult↗

[Klatskin's tumor].

During the period 1989-1998, 27 patients with primary proximal bile duct cancer were treated (17 females and 10 males with a mean age of 61 years). The main presenting symptoms were: jaundice (96.2%), itching (92.5%), weight loss (74%) and atypical pain (33.3%). All the patients underwent ultrasound (US) examination, 7 patients endoscopic retrograde cholangiopancreatography (ERCP) and 4 patients computed tomography (CT) examination. US examination revealed the tumor in 51% cases; most frequently a dilatation of the intrahepatic bile ducts was diagnosed with all methods. 8 patients underwent resection of the tumor and one a biliary-enteric anastomosis, in 15 cases a stent was inserted. In 3 cases the extension of the malignancy did not allowed any procedure. Three patients died during immediate postoperative period (mortality 11.2%). The mean survival was 13 months after stenting and 22 months after resection of the tumor. The authors recommended an aggressive surgical therapy for Klatskin tumors.

Adult↗

Abdominal pregnancy. Case report, review of the literature.

Abdominal pregnancy (AP) is a rare form of ectopic pregnancy (EP). It is a medical emergency because of high maternal and fetal morbidity and mortality. Early diagnosis is essential. Surgery is indicated as soon as the diagnosis is made. We present a case with AP in the third trimester with malformed fetus and left ovarian tumour. The fetus has been extracted at 33 weeks gestational age; the placenta and the ovarian tumour have been removed five weeks later. Pathology showed corpus luteum with hemorrhage, serous cystadenoma, follicular cyst. The fetus died, the woman successfully recovered.

Adult↗

[Case of cystic metastasis of the liver].

The report is about a patient clinic of Iassy from oncologic clinic. He had pain in the right, back and inferior hypocondrium, with irradiation, vomitings, pain less (7 kg in 2 months), weekness. The echography shows three years ago, hepatic cysts (the patient refused the admitted in hospital). Computed tomographic (CT) exam made in jan. 1996 shows three cystic hepatic tumors (2 in right and 1 in left lobes). The CT function revealed sterile biliohematic liquid. The laparotomy made the sharp diagnosis--cephalic pancreatic tumor with cystic metastatic hepatic tumors. The surgical treatment was partial resection of pancreatic tumor and drainage of hepatic cysts, with good postoperator evolution. The intraoperative histological exam found the same kind of malignant tumor in the pancreas and liver. We present the case for his rarity.

Humans↗

[Renal cell carcinoma- diagnosis by computed tomography].

In approximately 10% of cases, renal cell carcinoma (RCC) could present as a fluid- filled cystic mass. There are three mechanisms by which RCC may become cystic: extensive cystic necrosis, intrinsic cystic growth and origin from the epithelium lining a simple renal cyst. Simple renal cysts are very common. Uncommonly these cysts are complicated by hemorrhage, infection and possibly ischemia. The goal of the radiologist in evaluating these cystic lesions is to distinguish malignant neoplastic cystic masses from non-neoplastic complicated cysts so that appropriate management can be undertaken: RCC is best treated by surgical excision while non-neoplastic complicated cysts do not require surgery. The radiologic findings in these cystic masses which must be carefully evaluated include calcification, abnormal density, septations, nodularity, wall thickening and enhancement.

Carcinoma, Renal Cell↗

[Small size cephalo-pancreatic cancer. Demonstration of MRI/MRCP usefulness].

48 years old woman with obstructive jaundice has been examined by abdominal ultrasound followed by MRI. The suspicion of cephalic pancreatic cancer raised by ultrasound was confirmed by MRI and MRCP. Association of MRCP with axial and coronal T1 and T2 sequences successfully demonstrated a resectable tumor, confirmed at surgery. MRI/MRCP is demonstrating great potential in predicting resectability of cephalic pancreatic tumors.

Adenocarcinoma↗

[Role of computerized tomography in the diagnosis of transitional cell carcinoma of the upper urinary tract].

PURPOSE: To evaluate the computed tomography (CT) semiological criteria used in the diagnosis of transitional cell carcinoma of the upper urinary tract. MATERIALS AND METHODS: 26 patients with transitional cell carcinoma of the upper urinary tract underwent preoperative CT. In all cases nephroureterectomy was performed and CT and histopathologic findings were compared. RESULTS: 16 tumors were infiltrative and 10 tumors were sessile. The smallest tumour had 7 mm diameter and the largest one 13 cm. Associated focal hydronephrosis appeared in 11 cases and diffuse hydronephrosis in 7 cases. The vast majority of these tumors (69.23%) had a 21 to 50 Hounsfield Units enhancement. CONCLUSIONS: CT is a powerful tool to diagnose transitional cell carcinoma of the upper urinary tract when data acquired in intravenous urography and echography are equivocal.

Aged↗

[Transitional cell carcinoma of the upper urinary tract- staging by computed tomography].

PURPOSE: To determine the accuracy of computed tomography (CT) in staging transitional cell carcinoma of the renal pelvis and calyces and to identify whether hydronephrosis proximal to the tumor used as a criterion for minimal invasion may improve the overall accuracy of the method. MATERIALS AND METHODS: 24 patients with transitional cell carcinoma of the upper urinary tract underwent preoperative CT. In all cases nephroureterectomy was performed and CT and pathologic staging were compared. RESULTS: Pathologic staging revealed two stage I tumors, eight stage II tumors, five stage III tumors, and 9 stage IV tumors. The initial overall CT staging accuracy was 66.66% (16 of 24 patients). Reevaluation of the CT studies by using proximal hydronephrosis as a criterion for minimal invasion improved the overall CT staging accuracy (83.33%). CONCLUSIONS: When CT demonstrates direct tumor extension through the pelvic wall, it is a sensitive indicator of high-stage tumor. Hydronephrosis proximal to the tumor may cause overstaging of stage 0-II disease.

Aged↗

[Plunging ranula].

The plunging ranula is a relatively uncommon phenomenon which represents a mucus escape reaction occurring from disruption of the sublingual salivary gland. We present a retrospective study over a 10 years period on patients suffering of plunging ranula treated in Oral and Maxillo-Facial Clinic, resumed by a clinical example. These 7 patients with plunging ranula are related to all the patients operated for ranula in the same period of time in our clinic and were analyzed on age, sex, imaging exploration technique, treatment, and outcome. We found this kind of lesion both in children and young adults, between 10 to 40 years, more frequent on male (1.33/1). Two patients presented only the cervical form of ranula instead of the other five patients (both oral and cervical ranula). Only two of them received IRM examination. All of them received surgical treatment, the approach being cervical; it was removed both the cyst and the sublingual salivary gland. The surveying period, except the last case, was 1 year and includes no recurrences. We consider, besides esthetic loss that the cervical approach of plunging ranula seems to be the optimal access both on lesion and sublingual gland.

Adolescent↗

[MRI in acute pancreatitis].

26 patients with clinical and biological suspicion of acute pancreatitis were examined by MRI. The general indications for pancreatic MRI were: suboptimal or equivocal CT or ultrasonography findings (e.g. focal pancreatic enlargement with no mass discernable on CT or US), contraindications to iodinated contrast administration (e.g. contrast allergy history and renal failure). Using fast scanning techniques most of them with breath holding and fat saturation MRI was able to depict the lesions involved (e.g. the presence and distribution of necrotic areas and fluid collections, the existence of subsequent chronic pancreatic changes) which are consistent with CT findings. MRCP demonstrated etiology, like cholelithiasis.

Acute Disease↗

Continuous electrocardiographic monitoring during balloon dilatation in achalasia.

Electrocardiographic (ECG) changes in nine patients under continuous ECG monitoring before, during and after balloon dilatation for achalasia were followed; of these, three had ischaemic heart disease (IHD). One or several abnormalities including sinus tachycardia, supraventricular or ventricular ectopic beats, S-T segment depression and T-wave flattening appeared during the procedure; these were more commonly found in patients with IHD. Despite the high incidence of recorded ECG abnormalities, these were transient, and no treatment was needed. However, it seems advisable to have resuscitation equipment and emergency drugs available during balloon dilatation for achalasia, particularly when this procedure is performed in patients with IHD.

Adult↗

[Hepatic abscesses].

The authors analyse 16 cases of hepatic abscesses recorded in a 10-year interval. The difficulties in assessing the etiology and diagnosis, as well as in indicating an effective treatment are discussed. The clinical aspects and investigation methods, among which scintigraphy, arteriography and especially echotomography are extremely useful in making the diagnosis and in localizing the collection, are reviewed. The bacteriological examination revealed the presence of various organisms in 14 patients, the examined specimen of pus being negative in the remainder of 2 cases. The treatment was surgical in most of the cases (15) consisting in an abdominal approach or posterolateral with rib resection (1 case) and drainage. In 3 cases the intervention was extended to cholelithiasis which was the underlying cause of the abscess. The ultrasound-guided transparietohepatic drainage was performed in 2 cases. No death was recorded.

Adolescent↗