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Biomedical subjects

C D Teates

Publications and source records attributed to C D Teates.

At least 91 records · Page 5Linked to original sources

Gallium scanning as a screening test for inflammatory lesions.

Of the 67-Ga scans obtained in 42 patients with fever and suspected inflammatory lesions, 17 were positive. In 9 patients the scans yielded information about localized inflammation not provided by previous studies. Four patients did not have an inflammatory lesion at the positive site. Ten of 13 abscesses or inflamed wounds visualized and those not demonstrated were resolving without complication. Scans were normal in most patients with viral illnesses and nonlocalized inflammatory lesions. In 8 of 9 patients with fever of unknown origin the scan was normal. normal scan did not rule out inflammatory lesions but no significant localized pyogenic lesions were missed.

Abscess↗

Thermographic changes following preoperative radiotherapy in head and neck cancer.

Thermography was used to assess vascular changes during and after head and neck irradiation in an attempt to predict the optimum time for surgery for patients receiving preoperative radiotherapy. Thermography is performed every one or two weeks throughout treatment and at longer periods after treatment. Eight of the 16 patients studied has an initial decrease in temperature during the first two weeks. The maximum increase was observed during the fifth week after receiving 5,000 rads. Return to pretreatment temperature levels was a gradual process, occurring between three and six weeks after completion of radiotherapy.

Head and Neck Neoplasms↗

Use of thermography to evaluate the optimum time for surgery after preoperative radiation.

At the University of Virginia Hospital, patients undergoing preoperative irradiation for carcinoma in the head and neck region are usually scheduled for surgery four to six weeks after completion of therapy. Since preoperative irradiation produces no significant difference in the operative difficulty or postoperative morbidity, it is assumed that the vascularity of the area has returned to the pre-treatemtn level. Thermography is being used to quantitatively gauge the amount of vascularity and thus, help predict the optimum time for surgery. Thermography is obtained at two-week intervals after a pre-treatment baseline and is carried out for eight weeks after completion of therapy. During therapy the vascularity as determined by thermography is noted to increase to a maximum at approximately three to four weeks or 3 to 4,000 rads. Following completion of treatment, the vascularity subsides gradually and returns to the pre-treatment level at four to six weeks after completion of therapy.

Follow-Up Studies↗

The value of Gallium67 scanning in the evaluation of head and neck malignancy.

Gallium (67Ga) citrate is a scanning agent that has been shown to have a differential uptake in a variety of malignancies. Investigation of the usefulness of 67Ga scanning patients with proven squamous cell carcinoma of the head and neck region is now in progress. These patients have a 67Ga total body scan as part of the pre-treatment evaluation. The accuracy of the procedure is then judged by correlation with clinical and surgical findings. The results in 25 patients show that a clearly positive uptake occurs in 60 percent in the region of the primary. Uptake in metastatic disease in lymph nodes is much less, occurring in 6 of 18 sides of the neck. In one case, where clinical examination was considered to be negative, the gallium scan was positive and subsequently proven to be correct by histological examination of the surgical specimen. The various difficulties encountered in interpreting gallium scans in the head and neck region are described. It is felt that by improved patient selection and special techniques the yield of positive cases can be improved and unsuspected extension of malignancy demonstrated.

Carcinoma, Squamous Cell↗