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Biomedical subjects

C D Sherman

Publications and source records attributed to C D Sherman.

33 records · Page 2Linked to original sources

The International Union Against Cancer (UICC) and its Professional Education Program.

The International Union Against Cancer (UICC) is a world federation composed of 242 member organizations. One of its functions is organizing a quadrennial international cancer congress. The next congress will be held in Budapest in August, 1986. Other UICC programs include a Detection and Diagnosis Program, a Tumor Biology Program, a Public Education Campaign, Fellowships and Awards Program, Epidemiology and Prevention Program, Smoking and Cancer Program, Treatment and Rehabilitation Program, and the Professional Education Program. The latter produces a UICC Manual of Clinical Oncology, sponsors regional education meetings, offers consultation visits on request, and offers courses and training programs. The American activities are coordinated by the USA National Committee on the UICC, comprised of representatives of the United States members of the UICC.

Congresses as Topic↗

Assessment of jejunoileostomy for obesity--some observations since 1976.

In this review, which only partially covers the data available, it is pointed out that the evaluation of the results of jejunoileostomy may depend upon the criteria used by the observers, and disclosure of the true effects of the operation may depend upon the long-term follow-up of the patients. With increasing length of observation, it has become apparent that problems such as vitamin D deficiency, renal stone formation, continued steatorrhea, gallstones, zinc and copper deficiency, and even renal failure may be seen with disturbing frequency. Some of these may be preventable, others may be correctable and, indeed, the overall incidence of genuinely severe problems may, in the long run, be sufficiently low so as to make the benefits of jejunoileostomy outweigh the hazards. The rate of patient satisfaction is high, quality of life is generally improved and psychosocial and economic benefits of jejunoileostomy are apparent. The operation may also be a better alternative than the physical hazards of continuing obesity. Whether or not gastric bypass represents a true improvement over jejunoileostomy will depend upon the conclusions reached after applying to it the same searching scrutiny that is being used to examine the long-term results of jejunoileostomy.

Bile Acids and Salts↗

Fecal fat, bile acid, and sterol excretion abd biliary lipid changes in jejunoileostomy patients.

Fecal fat, bile acid, and neutral sterol excretion and biliary bile acid, phospholipid, and cholesterol were studied in 36 patients 6 to 12 months after jejunoileostomy for obesity. No relationship was observed between the degree of steatorrhea and weight loss, although fecal fat rose sharply in all except 2 patients. Mean neutral sterol excretion in feces was unchanged after operation except in cholecystectomized patients. No relationship could be demonstrated between serum cholesterol decrease and fecal biel acid, which rose 3-fold, or between cholesterol and the sum of fecal fat and neutral sterol. Fecal excretion of cholic and deoxycholic acid together increased more than the total excretion of cxcretion patterns were demonstrable: moderate fecal fat (24 g or less on 65-g intake) was associated with a predominance of secondary bile acids in feces and in bile; high fecal fat (above 24 g/day) was associated with predominantly primary bile acids. A high incidence of gallstones or previous cholecystectomy (36%) was found preoperatively and of 25 patients with normal cholecystograms, four developed stones and five had nonvisualization of gallbladder 6 to 12 months postoperatively. Bile saturation ratio and lithogenic index were not consistently changed postoperatively. No clear cut increase in lithogenic potential or in bile acid (lithocholic acid) hepatotoxic potential after jejunoileostomy was demonstrable.

Bile↗

Tobacco legislation.

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Legislation as Topic↗