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Biomedical subjects

C D Molteno

Publications and source records attributed to C D Molteno.

29 records · Page 2Linked to original sources

Cerebral palsy in Cape Town: A review of 389 coloured children.

Three hundred and eighty-nine Coloured cerebral palsied children were reviewed with regard to clinical type and its relationship to aetiological factors. There was no significant change in type or severity of case over two 6-year periods. Associated handicaps were also analysed, and the prevalence of these stresses the need for comprehensive assessment and treatment clinics so that multidisciplinary treatment can minimize the extent of the disabilities.

Adolescent↗

The adoption of the 'at risk' baby.

The high incidence of cerebral palsy among adopted children in Cape Town has long been a cause for concern. Five such children from a recent series of 12, in which pre- and perinatal histories were known, were high-risk infants. All were thought to have been normal at the time of adoption. The need for expert medical examination before adoption is stressed, risks that adoptive parents must take are evaluated, and the psychological aspects of delaying adoption are also considered. Some suggestions are made for modifying the existing adoption procedures in this country.

Adoption↗

Cerebral palsy in Cape Town: a comparative 12-year retrospective study.

Three hundred and thirty-one Coloured and 175 White children with cerebral palsy, born between 1964 and 1975, were compared as regards aetiology and changing incidence over two 6-year periods. The following were the main points which emerged: (i) there is an apparent decrease in the total number of White children with cerebral palsy born in the second 6-year period, but for reasons discussed, there is probably little or no true decrease; (ii) there is a significant increase in the total number of Coloured cerebral palsied children born in the second 6-year period, due mainly to an increase in cases of cerebral palsy of perinatal origin, particularly cases of perinatal asphyxia; (iii) there is a high incidence of acquired cerebral palsy in both racial groups, but this is significantly higher amont the Coloured; (iv) ther is no racial difference in the incidence of cerebral palsy in babies of low birth weight; (v) both racial groups have a fairly high incidence of cerebral palsy due to kernicterus. It is interesting to speculate whether improved obstetric and neonatal care and the resultant lowering of perinatal mortality produce more handicapped babies.

Age Factors↗

Acid-base determinations in normal and asphyxiated term infants during the first 24 hours of life.

Vigorous term infants who are born normally initially have a moderate metabolic and respiratory acidosis which is corrected by the time the infant is 6 hours old. Asphyxiated infants consistently show a greater degree of acidosis, both metabolic and respiratory. Caesarean section results in higher pCO2 values, especially when 'diffusion apnoea' occurs. Indications for the correction of acidosis in asphyxia are proposed.

Acid-Base Equilibrium↗

Infants of very low birthweight: a follow-up study.

The survival, growth and neurodevelopmental status of a group of non-White infants of very low birthweight, who were managed in the Neonatal Intensive Care Unit of Groote Schuur Hospital, is reported. The effect of certain high-risk perinatal factors on this status is assessed.

Birth Weight↗

Evaluation of preschool children with Down's syndrome in Cape Town using the Griffiths Scale of Mental Development.

Fifty-five preschool children with Down's syndrome were assessed using the Griffiths Scale of Mental Development. They were all the children with Down's syndrome living in Cape Town who spoke English or Afrikaans as their home language. There was a significant decrease in developmental quotient with increasing age and the hearing and speech subscore was lower than the other subscores. No significant associations were found between maternal age, sex, social class or race of the child and development. There was a negative association between developmental quotient and the number of siblings. The additional stimulation of a playgroup or preschool centre was associated with improved developmental functioning when compared to the children cared for at home during the day.

Child Development↗