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Biomedical subjects

C D Flower

Publications and source records attributed to C D Flower.

88 records · Page 5Linked to original sources

Localised airway narrowing in sarcoidosis.

Four patients developed multiple narrowings or occlusions of bronchi during the early stages of sarcoidosis when the chest radiograph showed no evidence of pulmonary fibrosis. Three of the patients had symptoms of breathlessness and wheezing and all had an obstructive defect of ventilation. Bronchography showed stenoses that were not apparent at bronchoscopy. It is concluded that the possibility of bronchial narrowing should be considered in patients who develop breathlessness or wheezing at any stage of sarcoidosis, and that bronchoscopy should be supplemented by bronchography.

Adult↗

Ultrasound of the pleura: an assessment of its clinical value.

In a prospective study, A mode ultrasound scanning contributed to the diagnosis and management of 24 of 50 consecutive patients with pleural disease. In 30% of patients it was superior to radiology in clarifying the solid or fluid nature of a pleural opacity, and in 42% of patients it allowed selection of the most appropriate site for the aspiration of pleural fluid. The technique is simple and the apparatus is widely available. We believe that ultrasound is an important practical aid in the diagnosis and management of pleural disease.

Humans↗

Megacalices--how broad a spectrum?

Ten patients with a suspected diagnosis of megacalices have had pressure-flow studies to confirm or exclude obstruction. Eight had no evidence of obstruction and amongst these there were 2 patients with a non-obstructed megaureter. Two patients showed evidence of obstruction and remain a dilemma from a management viewpoint. If "megacalices" is used simply as a descriptive term, then the spectrum of disease is wider than previously suspected.

Adolescent↗

Ultrasound in the diagnosis and management of pleural disease.

A-mode ultrasound investigation has been performed in 62 patients, of whom 35 presented problems of diagnosis and management of pleural disease. In seven patients with known pleural effusion in whom aspiration had failed ultrasound correctly identified fluid at a site different from the aspiration attempts and in all seven cases it weas successfully removed. The remaining 28 patients had the radiographic appearances of localized pleural disease and ultrasound correctly distinguished fluid and solid lesions in 26. We found ultrasound to be a simple and reliable technique which was particularly valuable in locating fluid for aspiration and in distinguishing between fluid and pleural thickening. The simplicity and 'bedside' availability of ultrasound offered certain practical advantages over radiography.

Adult↗

Percutaneous needle biopsy of thoracic lesions--an evaluation of 300 biopsies.

The results of 300 consecutive thoracic needle biopsies have been evaluated. It is concluded that this is a safe procedure for the investigation of peripheral intrathoracic masses. It should not be performed unless excellent facilities for cytopathology are available. Under these conditions there is a high degree of accuracy in differentiating between malignant and non-malignant lesions, particularly if repeated biopsies are performed when the initial results are unrewarding, equivocal or at variance with the radiographic appearances. In this series there was an imperfect correlation between the cytological and subsequent histological cell type except with squamous carcinomas. The indications are changing with the advent of flexible bronchoscopy and the increasing use of chemotherapeutic regimes. Misleading results may be obtained from biopsy of cavitating lesions and necrotic tumours.

Adolescent↗

Perforated oesophagus: review of twenty-eight consecutive cases.

Oesophageal perforation is a potentially lethal condition which requires early diagnosis and prompt surgical management. The radiological features in 28 patients with oesophageal perforation have been reviewed and correlated with the aetiology and site of perforation, underlying oesophageal abnormality and the time interval between occurrence and diagnosis. Twenty-five patients (89%) had detectable abnormalities on the chest radiograph. The commonest abnormalities were air in the cervical or mediastinal soft tissues and air or fluid in the pleural cavity. The factors influencing the different radiographic signs are discussed. Studies with a suitable contrast medium are necessary to show the site and extent of the perforation, the extent of any associated abscess cavity and the position of the perforation relative to any primary oesophageal disease. Of 26 patients who had a barium swallow a leak was demonstrated in 21 (81%). In the five patients in whom no leak was demonstrated the examination was performed more than 24 h after the perforation.

Esophageal Perforation↗

Ureters that show both reflux and obstruction.

Eight ureters in 6 male patients have been shown radiographically and dynamically to exhibit both reflux and obstruction. The greater the degree of obstruction the more dilated the upper urinary tract. Reflux may be considerable, but in severely obstructed ureters it may be minimal. Both urologists and radiologists should be aware of this unusual association. When it occurs patients should not be managed conservatively, but should have their ureters reimplanted.

Adult↗

The lungs in lymphangiomyomatosis and in tuberous sclerosis.

Two cases of pulmonary lymphangiomyomatosis (PL) are described and 33 other cases from the literature are reviewed. These are compared with one case of tuberous sclerosis with pulmonary involvement (PTS) and 32 other cases from the literature. There are no differences in lung function between these two conditions, both of which show airways obstruction associated with diffuse radiological lung changes. There are, however, both clinical and radiological differences and also differences in the distribution of the lesions and the histological location of the excessive smooth muscle; these indicate that PL and PTS are probably different entities and not polar forms of one condition. Finally, the strictly female incidence of PL suggests a sex-linked disorder, and it is postulated that this may be related to congenital pulmonary lymphangiectases.

Adolescent↗

Radiological evaluation of the ascending aorta following repair of type A dissection.

A patient with persistent chronic dissection proximal to an aortic interposition graft for repair of a type A dissection prompted us to review the computed tomographic (CT) findings in 14 other such patients 5-47 months after surgery. No other case of proximal aortic dissection was identified although dilatation of the aortic root proximal to the graft was present in 8 patients (57%). Persistent dissection distal to the graft in 11 patients (79%) was in keeping with that reported by other workers. Chronic dissection proximal to the surgical repair of a dissection seems a rare although important complication.

Aortic Dissection↗