False positive reaction to mercaptobenzthiazole from rubber in eyedrop bottle.
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Biomedical subjects
Publications and source records attributed to C D Calnan.
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An outbreak of occupational dermatitis in an electroforming plant where there was heavy exposure to nickel is described. Patch test investigations confirmed nickel allergy in 13 of 27 exposed individuals. Nickel chloride was found to be a more reliable patch test allergen than nickel sulphate. Improvements in industrial hygiene led to an immediate decrease in the incidence of dermatitis. Persistent patch test sensitivity to nickel was found in three individuals who had been removed from the process chemicals for some years.
Dermatitis is reported from slimicides added to wood pulp slurry in a paper mill. The active constituents of the slimicides involved were bis-1,4-bromoacetoxy-2-butene and 2,3-dichloro-4-bromotetrahydrothiophene-1,1-dioxide. Wood pulp slimicides include many chemicals which are highly irritant and potentially sensitizing to the skin.
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An outbreak of irritant dermatitis from a cyanoacrylate glue among a group of electronic assembly workers is described. It was caused by vaporization of monomer under conditions of low relative humidity. No further outbreak occurred when the humidity of the working environment was raised above 55%.
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