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Biomedical subjects

C Creusy

Publications and source records attributed to C Creusy.

At least 19 recordsLinked to original sources
PubMed1999

[Symmetrical benign lipomatosis of the tongue and Launois-Bensaude lipomatosis].

BACKGROUND: There are many causes of macroglossia, including fatty infiltration. Unlike unique or multiple lipomas of the tongue, non-encapsulated adipocyte masses develop in the tongue in symmetrical benign lipomatosis. Only six cases have been reported in the literature. CASE REPORT: A 69-year-old man with a history of chronic alcoholism developed a soft tumefied formation on the lateral margins of the tongue. A yellow-colored content was perceived through the thin mucosa. The formation was bilateral and had developed for more than 10 years. The patient also presented Launois-Bensaude lipomatosis localized on the neck, the nuchal region and the shoulders. DISCUSSION: This is, to our knowledge, the first reported case of symmetrical benign lipomatosis associated with Launois-Bensaude lipomatosis. An analogy between these two conditions has been suggested, but the six earlier cases of lipomatosis of the tongue reported in the literature developed in patients without cutaneous lipomatosis.

Aged↗
PubMed1998

Morphological and ultrastructural methods for Pneumocystis.

Pneumocystis is a eukaryotic unicellular microorganism with marked fungal affinities. All known life cycle stages of this parasite were observed in the lung of mammals. The cystic forms of this microorganism may be observed microscopically by using stains with affinity for the components of their relatively thick cell wall. However, about 100 years ago they were observed for the first time thanks to panoptic stains which do not stain their cell wall. Methanol-Giemsa technique as well as Giemsa-like rapid stainings are often used to reveal vegetative or cystic forms of this parasite on air dried smears of clinical or experimental samples. For many years, hypotheses on its life cycle, which remains unknown, were based on transmission electron microscopy (TEM) studies. However, only for the last years progresses in the quality of fixation for TEM led to a better understanding of the Pneumocystis cell structure. In this chapter, strategies to reveal Pneumocystis organisms in clinical or experimental specimens by using light microscopy, as well as techniques allowing a good preparation of parasitic samples for TEM, are given and shortly discussed.

Animals↗
PubMed1997

Colonic obstruction and perforation related to heavy Trichuris trichiura infestation.

Heavy Trichuris trichiura infestation is rare in developed countries, and complications requiring surgical intervention have been described rarely in human trichuriasis. A case of colonic obstruction and perforation related to heavy whip-worm infection is described in an 84 year old woman. The woman was admitted to hospital because of a chest infection. Two days after admission she suffered nausea and vomiting followed a day later by bowel stoppage. Laparotomy indicated intestinal obstruction by a tumour. A partial right sided ileocolectomy was performed. Pathological examination of the resected bowel revealed heavy infestation with T trichiura causing a pseudotumour following a proliferative inflammatory response.

Aged↗
PubMed1997

[Telepathology and "small cells" in cervical-vaginal smears: a new tool for diagnosis and teaching?].

The identification of small cells in cervical/vaginal smears is usually considered as a difficult task, as well when they are examined through a classical light microscope or thanks to a teletransmission system. In this paper, we have compared both methods. 53 cases of smears with small cells were examined by two pathologists. The different types of small cells were described. The results and the discrepancies were studied. The reliability was rather good (45/53 cases, 84.6%). The main images were recorded onto a videotape for teaching purposes.

Cervix Uteri↗
PubMed1996

[Hepatocellular carcinoma in asymptomatic primary biliary cirrhosis].

Hepatocellular carcinoma is an uncommon complication of primary biliary cirrhosis. Hepatocellular carcinoma occurs generally in the end stage of the disease. We report a case of asymptomatic primary biliary cirrhosis complicated by a hepatocellular carcinoma in a 66 year-old man.

Aged↗
PubMed1994

[Prevalence of hepatitis C, B and D markers and histopathological aspects in a group of intravenous drug addicts].

OBJECTIVES: The aim of this study was to assess the prevalence of infection by HCV, HBV, HDV and HIV and their biological and histopathological patterns in 104 intravenous drug users. METHODS AND RESULTS: Seventy-five patients (72%) had anti-HCV antibodies. Transmission was rapid because 33% of those who had been drug users for 6 months or less had anti-HCV antibodies. The contamination rate was very high because 90% of those who had been drug users for 2 years or less had anti-HCV antibodies. Thirty-four (33%) had an HBV marker, and 6 were HBs Ag carriers. None of the patients had anti-HDV antibodies. Only one patient had anti-HIV antibodies. Twenty-five anti-HCV antibody positive drug users underwent liver biopsy. Seven (28%) had normal ALAT levels and 18 (72%) had permanently or intermittently elevated ALAT levels. The mean histological activity on the Knodell index was 4.1 (range: 1-8). CONCLUSIONS: This study indicates that contamination by HCV is almost inevitable after 2 years of intravenous drug use. The low prevalence of HBV, HDV, and HIV infection might be explained by a low endemic state of these viruses in our area.

Adolescent↗
PubMed1990

[Ovarian tumor and Peutz-Jeghers syndrome. A case report].

A case of Peutz-Jeghers syndrome associated with ovarian mucinous cystadenoma and ovarian sex cord tumor with annular tubules is presented. The sec cord tumor with annular tubules was described in 1970 by Scully, who recognized its striking association with the Peutz-Jeghers syndrome. This tumor is an almost constant finding in patients' ovaries with this disorder. Three cases of ovarian mucinous cystadenoma and sex cord tumor with annular tubules associated with Peutz-Jeghers syndrome were found in the literature. Our observation confirms that gynecologic abnormalities are an important manifestation of the syndrome and require careful surveillance.

Child↗
PubMed1989

[Dermo-hypodermic lymphoid pseudotumors with follicular hyperplasia. Apropos of a case].

We report the case of a female patient with ubiquitously distributed cutaneous and subcutaneous nodules measuring 2 to 6 cm along their long axis. These nodules first developed at the age of 63 years and subsequently appeared in crops separated by spontaneous remissions. Studies of removed nodules demonstrated diffuse lymphoid follicular hyperplasia suggesting a tumor and raising difficult nosologic problems, especially regarding relationships with the extranodal multicentric Castleman syndrome. In march 1987, biopsy of a large scapular nodule spreading into the striated muscle suggested possible transformation into a low grade malignant lymphoma of the lymphoplasmocytoid type.

Biopsy↗
PubMed1989

[Chronic diarrhea caused by VIP-secreting ganglioneuroblastoma in children. Apropos of a case with a review of the literature].

A literature review was conducted in relation to a case of chronic diarrhea associated with a VIP (vasoactive intestinal polypeptide) producing ganglioneuroblastoma (GNB), in an 18-month old female baby. This is a rare entity characterized by premonitory, persisting diarrhea, causing fluid and electrolyte changes typical of the WDHA syndrome, associating watery diarrhea, hypokalemia, and achlorhydia. Elevated VIP plasma levels are an indication for an echographic and/or CT-scan search for the causal secreting tumor. Although the prognosis of this condition seems favorable, the recommended treatment is surgery. The VIP substance represents an excellent biological monitoring marker. Ganglioneuroblastomas are tumors of the sympathetic nervous system, which, according to Pearse's cell and embryologic theory (1966), have to be linked to the APUD system tumors (paraneuromas). VIP-producing forms are rare in children, and only 29 case studies have been compiled in the literature since 1970, when the VIP substance was discovered. The case reported in this study illustrates the diagnostic problems raised by such lesions, and allows us to confirm VIP's imputability for the occurrence of the chronic diarrhea condition in this child.

Chronic Disease↗
PubMed1989

[Leiomyoma of the bladder].

The authors report a case of bladder leiomyoma. They emphasise its rarity and the important role of medical imaging in its preoperative diagnosis, which can only be confirmed with certainty by histological examination. Treatment must be surgical with complete resection and the prognosis is excellent.

Humans↗
PubMed1988

[Eosinophilic bladder disease].

The authors present ten cases of eosinophil cystopathy and recall the very varied clinical signs of this disease: pollakiuria, haematuria, dysuria and the findings of complementary investigations: possible dilatation of the upper urinary tract, thickening of the bladder wall. Biopsy is essential and reveals lymphocyte and plasma cell infiltration and numerous eosinophils. The treatment administered was either immunosuppressants or dimethyl sulphoxide.

Aged↗
PubMed1987

[Primary liposarcoma of the left atrium surgically treated].

A case of myxoid liposarcoma of the left atrium in a 35-year old man is reported. The tumour, revealed by an atrial flutter, was excised. The patient died 13 months later, with multiple metastases. A review of the literature yielded only 7 cases of primary liposarcoma of the heart, including 4 which were surgically treated. This confirms the extreme rarity of a tumour which has a very poor prognosis due to recurrence in situ or metastatic spread.

Adult↗
PubMed1986

[Rheumatoid polyarthritis and interstitial cystopathy].

The authors report a case of interstitial cystitis occurring in association with very active rheumatoid arthritis. Although the association of immune disorders and rheumatoid arthritis is well known, cases of concomitant vesical lesions have only been reported exceptionally. The diagnosis of interstitial cystitis is based on histology and immunofluorescence studies. The pathogenetic hypothesis remains uncertain: is this a primary bladder disease or a systemic auto-immune disease with a urinary tract expression? The success of immunosuppressant treatment in this case of cystitis is in favour of the second hypothesis.

Arthritis, Rheumatoid↗