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Biomedical subjects

C Cope

Publications and source records attributed to C Cope.

At least 109 records · Page 6Linked to original sources

Balloon dilatation of closed mesocaval shunts.

Successful percutaneous balloon dilatations of four mesocaval shunts (one stenosis, three occlusions) and one acutely thrombosed portocaval shunt were performed in four patients with massive esophageal variceal bleeding. Shunt failure was acute (1-2 days) in two patients and delayed (1-2 years) in three. One patient died early in hepatic failure. Portocaval pressure gradients became normal in four patients and have been kept in the 11-16 cm H2O range by careful outpatient shunt pressure monitoring and, if indicated, redilatation at 6 months' interval. Transanastomotic coil occlusion of large esophageal varices was done in three patients. There has been no recurrent variceal bleeding in the four surviving patients over a period of 16 months.

Adolescent↗

Effects of maternal sedation during fetoscopy.

While instituting a new program in fetoscopy, the authors explored the effects of sedation with meperidine (Demerol) and promethazine HCl (Phenergan) during fetoscopy conducted on 10 mothers at 14 to 18 weeks' gestation. Each received 100 mg of meperidine and 50 mg of promethazine HCl approximately 30 minutes before the procedure. In 3 instances, a repeat half-dose injection was made at 30 minutes for adequate analgesia. Sex of the fetus was determined accurately in 9 instances. In 9 of 10 cases, visualization was satisfactory; technical problems in 1 case precluded visualization. Complications included 2 superficial fetal limb hematomas and 2 instances of minimal fetal bleeding from an unknown site. Three patients required perforation of anterior placentas. Amniotic fluid was invariably clear but became progressively turbid. Sedation allowed a longer period for clear amniotic fluid by decreasing fetal movements progressively over the first hour; fetal activity showed a prompt return thereafter. The clarity of the amniotic fluid was adversely influenced by external manipulation of the fetus. The authors conclude that sedation has obvious benefits for the mother and may facilitate evaluation of the fetus during fetoscopy.

Adult↗

Iatrogenic arteriovenous fistula: a complication of percutaneous subclavian vein puncture.

A case of iatrogenic subclavian arteriovenous fistula is reported. An intracath had been inserted percutaneously into the left subclavian vein to monitor the central venous pressure during aortic valve surgery. On the second postoperative day a thrill and continuous murmur were detected at the left subclavian region. Left subclavian arteriogram and catheterization studies confirmed the diagnosis of subclavian arteriovenous fistula. The lesion was treated surgically with satisfactory results.

Aortic Valve↗