Search PubMed⌕ Search

Biomedical subjects

C Conraux

Publications and source records attributed to C Conraux.

At least 55 records · Page 3Linked to original sources
PubMed1990

[Use of madreporic material in ear surgery. An initial study].

Numerous surgical techniques now call for biomaterials. Included in this term is material foreign to the receiver, of natural or artificial origin, which is implanted in a living organism in order to repair the impaired function of the organ. By using a recent material, coral, the authors here by relate their experience within the scope of ear surgery. The analysis of the preliminary results encourages the further use of this material, bio-compatible, easily-used and giving excellent functional results.

Biocompatible Materials↗
PubMed1989

[Cancer of the maxillary sinus. A retrospective study of 29 cases].

Representing 2% of malignant tumors and 6% of head and neck cancer, almost always diagnosed at a late stage, maxillary sinus cancer still remains a rather rare pathology but fearsome prognosis. From the 29 cases, over 10 years of follow up at the clinic and Paul Strauss cancer treatment center, this study focuses mainly on two criteria: diagnosis, in the study of the presenting symptoms in order to treat this pathology as soon as possible; therapeutic, by analysing our results, and by focusing on the current treatment.

Adult↗
PubMed1989

[Static and dynamic posturography. Application to a population of young athletes].

The authors used a vertical force platform fitted with 4 pressure gauges (Societe Toennies). The static regime provides the statokinesigram, the lateral and sagittal stabilograms and their Fourier transformations. Information is collected with the eyes open and closed, thereby allowing the Romberg quotient to be determined. In the dynamic regime, the platform unexpectedly tilts to a toes-up position (4 degrees at a rate of 50 degrees/s). The activity of the tibialis anterior and soleus muscles is recorded by integrated electromyography. The early soleal response, provoked by the myostatic reflex, is followed by later responses due to the vestibulo-spinal reflex. These various parameters were recorded in young athletes and the obtained tracings are commented on.

Adolescent↗
PubMed1988

[Captopril potentiation of the hypotension induced by halothane].

In a double-blind study, twenty-four ASA 1 and II patients scheduled for otosclerosis surgery were randomized in two groups according to the premedication given orally 1 h before anaesthesia: placebo (group P; n = 12) or 25 mg captopril (group C; n = 12). Anaesthesia was induced with thiopentone, fentanyl and vecuronium and was maintained, after oral tracheal intubation, with N2O/O2 (50/50); 5 min after intubation, the inspired halothane concentration (FIH) was set at 1.8-2% in order to obtain a mean arterial pressure (Pa) of 45-55 mmHg; thereafter, FIH was increased or decreased (+/- 0.5% every 3 min) in order to maintain this Pa value. Ventilation was controlled in order to assure normocapnia (35-40 mmHg). Inspired and expired (FEH) halothane concentrations were monitored by an halothane analyser. The plasma renin (ARP) and conversion enzyme activities (AEC) were measured before anaesthesia (ARP1, AEC1), 5 min (ARP2) and 55 min (ARP3, AEC2) after the start of anaesthesia. In group C, AEC1 and AEC2 were reduced by half, confirming the efficiency of captopril in inhibiting the conversion enzyme. ARP1 and ARP2 were increased in group C (5.42 +/- 4.2 and 9.92 +/- 7.35 micrograms.l-1.h-1. ARP3 increased in both groups (20.75 +/- 8.42 micrograms.l-1.h-1 in group C, and 24.60 +/- 15.40 in group P). Pa decreased to 55 mmHg more rapidly in group C (9 min in group C; 18 min in group P; p less than 0.05) and FEH could be reduced by a third (1.38 +/- 0.29% in group P; 0.90 +/- 0.17% in group C; p less than 0.05).(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗
PubMed1988

[Computer-assisted vestibular tests].

The labyrinth is a sensor of vibration. Therefore, multifrequency vestibular stimulation proves indispensable in obtaining a more accurate study of the VOR. We chose to use a pseudo-random binary sequence, generated on a mini computer. The angular velocity instructions are made up of eight repetitive sequences, the spectrum of energy in which is adapted to the frequency range of VOR. A process eliminating the quick phases, the blinking and other artefacts is applied to the nystagmic response, in order to observe only the slow phase velocity. The velocity of eye and chair are compared and the transfer function of VOR is performed. Gain, phase, coherence function and predominance of the mean slow phase velocity between left and right responses are the four indices which define VOR function. The multifrequency rotatory test is interesting for topographic diagnosis, and makes out three diagnostic ranges: a mechanical peripheral, a neurosensory peripheral and a central one. Two practical measures could help the propagation of this method: a simpler vestibular stimulation in order to suppress the rotatory chair, a simplified method of data processing using a personal computer.

Diagnosis, Computer-Assisted↗
PubMed1987

[Nasosinusal aspergillosis. Apropos of 35 cases].

Principal characteristics of clinical and paraclinical pictures of nasosinusal aspergillosis (NSA) in 35 patients are analyzed and allow distinction of three main types of this nasosinusal fungal lesion. Localized, non-invasive nasosinusal aspergillosis (NINSA) is frequently of dental origin and presents as a chronic maxillary sinusitis resistant to conventional treatment. Serology is negative or non-significant for Aspergillus and recovery is complete after surgery. Invasive nasosinusal aspergillosis (INSA) affects debilitated patients (diabetes, immunodepression, malignant blood disease...), and presents with bone destruction, extension to orbit, base of skull and intracranial region, following an acute or subacute course with positive serology for Aspergillus. Early, wide surgical eradication is combined with local and general antifungal therapy but prognosis is poor. Allergic nasosinusal aspergillosis (ANSA), of more recent description, combines chronic sinusitis with severe nasosinusal polyposis, and specific histologic and immunologic features. Its course is favorable with corticoid therapy but long-term results are unknown.

Adult↗
PubMed1984

[Opsoclonus. Oculographic recording].

The oculographic recording exposed by the authors in this study shows the difference between the opsoclonus and the abnormal movements: particularly the flutter and the dysmetria. The otologist must be interested to recognize it in his daily practice.

Adult↗
PubMed1983

[Technic and value of the carbachol nasal test in vasomotor rhinopathies].

The carbacholine nasal test assesses "nasal hyperreactivity", particularly its parasympathetic component, in vasomotor rhinopathies. This simple, reproducible test has been applied to two groups of subjects: a group of 26 healthy subjects without any rhinopharyngeal and/or allergic affections, and 10 patients with aperiodic non-allergic (6 cases) or allergic (4 cases) vasomotor rhinopathy, the 4 cases with allergy including 3 allergic to house dust mite and one to house dust mite and grass pollen. Nasal reactivity to carbacholine was evaluated by measuring the amount of rhinorrhea following variable concentrations (1/1000, 1/100, 1/25) and volumes (0,10 to 0,50 ml) of carbacholine solution. Nasal secretion was markedly increased in patients with a vasomotor rhinopathy (1.80 +/- 0.65 ml) when compared with control subjects (0.64 +/- 0.17 ml). The main conclusions to be drawn from this study, and possible applications of this test in rhinology are discussed.

Adolescent↗
PubMed1982

Ototoxicity of tobramycin in humans - influence of renal impairment.

The effects of prolonged tobramycin administration (given in repeated injections over a 15-day period) on auditory and vestibular functions were studied in normal subjects, in patients with renal impairment, and in chronic nephritic patients undergoing hemodialysis. With the doses used in this study, the repeated administration of tobramycin resulted in blood accumulation only in the group of patients with renal impairment. In one single case, administration of tobramycin was followed by a transient aggravation of a pre-existing renal impairment. Cochlear and vestibular functions were evaluated before treatment and repeated during and after drug administration. In normal subjects, a dosage of 50 mg/8 h failed to produce cochlear and vestibular dysfunction; but with dosages of 75 mg/8 h and 100 mg/8 h, changes in vestibular reflectivity occurred frequently, mostly of the irritative type. Generally moderate, but quite often slight changes persisted (5 of 10 cases). They were not accompanied by auditory or vestibular clinical signs. In patients with impaired renal function and in those undergoing chronic hemodialysis, vestibular impairment is customary and most often of the deficiency type. Half of the cases still showed detectable changes on follow-up evaluation that was performed 10 days after discontinuation of the drug.

Anti-Bacterial Agents↗
PubMed1982

Local and serum IgE in vasomotor rhinitis.

Total and specific IgE in serum and nasal secretions were measured in twenty five subjects with vasomotor rhinitis without asthma (21 perennial vasomotor allergic rhinitis and 4 seasonal vasomotor allergic rhinitis) after Carbacholine nasal challenge-test. The level of total and specific IgE was lower in the pure, non diluted nasal secretions than in the serum. The diagnostic usefullness of these measurements and the concept of "localized allergy" are discussed.

Humans↗
PubMed1981

[Rapid derived auditory evoked potentials].

Brain stem auditory-evoked responses to a 70 dB SL click masked by high-passed noises were recorded in 12 normal hearing subjects. By applying the technique of derived potentials, the contribution of one-octave-wide frequency bands are assessed. Summation of these derived potentials gives a pattern similar to the unmasked-response waveform. Waves I and III show a strong predominance of high-frequency responses, whereas wave V is discernible down to low-frequency responses.

Adult↗
PubMed1980

[Electronystagmograhy in disseminated sclerosis. Uses and limits (author's transl)].

A review of the literature shows the extreme frequency of nystagmus and changes in vestibular reflexes in disseminated sclerosis. During the course of this disease, it is possible to detect nystagmus in at least two-thirds of cases and in a similar proportion there are changes in vestibular reflexes, usually a hyperreflexia, especially in the early phases of disseminated sclerosis. Subjectively the patients rarely complain of vertigo and such symptoms are in any case part of the early form of the disease. On the other hand, disorders of balance are much more frequent but the factors involved are numerous, and the role of the vestibular system is often debatable. Electronystagmography and oculography demonstrate the extreme frequency of spontaneous or fixed gaze nystagmus in this disease, as well as the extreme frequency of changes in conjugated eye movements; changes in reflex, voluntary and automatic conjugated eye movements. As a matter of fact, there are many kinds of nystagmus which are not related to any changes in the vestibular system, but which are rather more part of the overal changes of conjugated eye movements. Seen in this light, electronystagmography and oculography, by exploring the different kinds of conjugated eye movement, can help decisively in the diagnosis of disseminated sclerosis by revealing changes which reflect damage to the brain stem, lesions which are clinically very often silent. In this way the diagnosis of disseminated sclerosis may be confirmed. Furthermore, electronystagmography can easily suggest another diagnosis, other than the early form of disseminated sclerosis of the vestibular type.

Electronystagmography↗