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Biomedical subjects

C Colosimo

Publications and source records attributed to C Colosimo.

At least 145 records · Page 8Linked to original sources
PubMedDate not supplied

Cushing's syndrome: new variants and association with empty sella syndrome.

In this article we propose a review of the literature on clinical variants of Cushing's syndrome (CS) and personal observations on one of these variants. Clinical variants of CS are: (1) tumors of the intermediate pituitary lobe; (2) hypothalamic Cushing's with pituitary hyperplasia; (3) cyclic CS; (4) primitive nodular adrenal dysplasia; (5) pre-Cushing's syndrome; (6) association of CS and empty sella. The personal observations relate to the association of CS and empty sella. This syndrome consists of: (a) inappropriate cortisol secretion of pituitary origin; this alteration is less pronounced in comparison with other patients affected by Cushing's disease; (b) marked hirsutism; (c) slight hyperprolactinemia or augmented PRL response after metoclopramide; (d) elevated DHEAS levels.

Adolescent↗
PubMedDate not supplied

[Computerized tomography in rheumatoid arthritis of the cranio-cervical junction].

Twenty rheumatoid arthritis (RA) patients with involvement of the cranio-cervical junction (CCJ) were given CT scan. In most cases the myelo-CT technique with the lumbar injection of small quantities of non-ionic contrast medium was adopted; CT easily diagnosed the "horizontal" and "vertical" dislocations on the CCJ, the bone structure lesions and the inflammatory masses. A high frequency of medullary compressions was also found in these patients. Myelo-CT appears to be the technique of choice for the precise definition of the various factors responsible for the neurological complications found in RA of the CCJ.

Adult↗
PubMedDate not supplied

[Cholecystography with ceruletide. Results and evaluation of its routine use].

Cholecystography has been up to day used as unique or first instance examination in patients suspected to have chronic gallbladder diseases. On the other hand, cholecystosonography is proposed with increasing frequence as first examination for simple and rapid detection of cholelithiasis. Results of high standard cholecystography are therefore welcomed in order to assess it present role in respect to diagnostic ultrasounds. On this basis, the authors reports the results of systematic administration of ceruletide in 300 clinically unselected patients with a good opacification at cholecystography. Ceruletide has been demonstrated to be rarely accompanied by a few minor side effects, to have a cholecystokinetic effect more rapid and intense than fatty meal and cholecystokinine and to be followed by frequent diagnostic visualization of cystic duct and choledochus. Small gallbladder stones, diffuse and segmentary cholecystosis and cholecystostasis, with clinical relevance, were easily detected and may be therefore considered as elective indications of ceruletide-assisted-cholecystography. Systemic administration of ceruletide in the course of cholecystography is apt to push its diagnostic possibilities to a maximum extent, allowing appropriate comparison of effectiveness with cholecystosonography in view of their complementary role.

Adolescent↗
PubMedDate not supplied

[Progressive multifocal leukoencephalopathy in patients with AIDS. Findings with computerized tomography and magnetic resonance].

Progressive Multifocal Leukoencephalopathy (PML) is a subacute demyelinating opportunistic infection of the central nervous system which frequently occurs in AIDS. CT and MR, together with clinical and virological findings, can suggest a correct diagnosis in most cases, thus avoiding stereotactic biopsy which is too invasive considering the lack of therapy and the poor prognosis of this disease. In this study we reviewed the CT and MR findings of 16 proved AIDS-related PML cases. PML lesions appeared as hypodense on CT, hypointense on T1w, hyperintense on PDw and T2w MR images. CT was less sensitive than T2w MR images and underestimated the number of lesions and/or disease extent. On the basis of our findings during the progression of the lesions we observed two different patterns of PML presentation and evolution i.e., "single" and "multifocal". Single lesions generally involve subcortical white matter (arcuate fibers) of parietal lobe and spread to the contralateral hemisphere across the corpus callosum; multiple "patchy" lesions can be localized variably in the cerebral hemispheres and also in the brainstem and cerebellar hemispheres.

Acquired Immunodeficiency Syndrome↗
PubMedDate not supplied

Central pontine myelinolysis: report of an asymptomatic case.

Central pontine myelinolysis (CPM), a disorder occurring for the most part in alcohol abusers, is characterized by the symmetric and selective destruction of medullated sheaths in the central pontine region. Detection of CPM in the pre-symptomatic phase may improve the outcome, which is usually serious. We describe a case of CPM in a 48-year-old female alcohol abuser who was seen at our out-patient clinic for a history of generalized seizures. Neurological examination was normal while magnetic resonance imaging revealed a pontine lesion consistent with CPM. On the basis of this report we hypothesize that the possibility to detect CPM in the pre-symptomatic phase will lead to increased diffusion of magnetic resonance imaging, and in turn to improved therapeutic strategies, such as the use of greater caution when correcting plasma electrolyte imbalance in alcoholics.

Electroencephalography↗
PubMedDate not supplied

Gliomatosis cerebri: report of an atypical case.

Gliomatosis cerebri (GC) is a rare, diffusely infiltrating tumor of neuroepithelial origin. The clinical diagnosis is difficult since GC is a diffuse and progressive disease of the central nervous system (CNS). Non-specific findings can be detected by computed tomography (CT) whereas, according to some authors, the extent of this tumor can be accurately depicted by magnetic resonance imaging (MRI). In this paper the neuroradiologic, neuropathologic and immunohistochemical features in a further case of GC are reported.

Adult↗
PubMedDate not supplied

Brain stem gliomas.

Explore the source record for details and available documents.

Brain Neoplasms↗
PubMedDate not supplied

Tumors of cerebral hemispheres.

Pediatric brain tumors are substantially represented by neuroepithelial neoplasms. If intraventricular tumors are excluded, diagnostic imaging can be referred to 3 main types: gliomas, neuronal and mixed tumors, embryonal tumors. Following a short review of the various neuroimaging procedures, CT and MRI findings of most common pediatric hemispheric neoplasms, are described. Neuroradiologic findings supply a satisfactory "characterization" of the neoplasm. They are at times so specific as to achieve a univocal diagnostic hypothesis. More frequently, only a likely histologic hypothesis is achieved based on the combination of neuroimaging and clinical findings. Finally, the role of diagnostic imaging is underlined, being important in the definition of the relationships between hemispheric tumors with some "critical" areas, because of "functional" relevance, and in the identification of the site and pattern of infiltration which impact on prognosis and treatment.

Adolescent↗