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Biomedical subjects

C Collins

Publications and source records attributed to C Collins.

281 records · Page 16Linked to original sources

Reverse isolation: what patients perceive.

This study looked at patients' perceptions of reverse isolation while undergoing autologous bone marrow transplant (ABMT). Persons in reverse isolation experience both obvious and less evident stressors. To understand patients' perceptions of these stressors, semi-structured audiotaped interviews were held periodically during isolation (21-25 days) with six subjects receiving ABMT. This identified recurrent themes, which were than validated in a final interview. Most subjects understood the rationale of reverse isolation, and many prepared by bringing objects of personal value with them. Few mentioned feeling restricted by the room after the initial days. Some patients used the TV, VCR, radio, and telephone as "extensions to the world," as well as for entertainment. Subjects found visits from their main supports very important in coping with feelings of isolation. The patients' emphasis on a variety of ways to pass time was particularly interesting. The overall finding, however, was that the physical side effects of the treatment brought more distress than the isolation.

Adaptation, Psychological↗

Cardiotoxicity of 5-fluorouracil.

Three patients developed anterior substernal chest pain in association with ischemic electrocardiographic changes temporally related to continuous infusions of 5-fluorouracil (5-FU). Two patients developed myocardial infarctions and one died. Cardiac toxicity of 5-FU may be more likely when the drug is given by continuous infusion in the presence of preexisting cardiac disease. The pattern of cardiac toxicity suggests cardiac ischemia most likely secondary to coronary artery vasospasm. Patients should not receive 5-FU by infusion if they have significant underlying coronary artery disease or if they develop anterior substernal chest pain while receiving the drug.

Aged↗

Caregiving transitions: changes in depression among family caregivers of relatives with dementia.

Depression among family caregivers of relatives with dementia was examined at three time intervals over a 4-year period. Comparisons were made between 46 residential caregivers, 49 caregivers of institutionalized elders, and 47 bereaved caregivers. No overall difference was found between the depression paths of the three groups. Female bereaved caregivers experienced a pattern of decreasing depression following their relative's death, while male bereaved caregivers experienced an increase in depression. Findings suggest the need for further investigation of the influences of gender on bereavement following the experience of providing family care for a relative with dementia.

Aged↗

Breaking the chains.

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Ethics, Nursing↗