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Biomedical subjects

C Colin

Publications and source records attributed to C Colin.

152 records · Page 9Linked to original sources

[Premenstrual mastodynia: objective signs (author's transl)].

Mammary congestion is mainly a painful syndrome, principally related to diffuse edema of the gland, the radiological signs of which are described in this report. Excellent validity can be obtained by a trained observer of these signs. In contrast, however, thermographic signs are of less value, probably due to the presence of a more or less abundant superficial edema. This interferes with thermal propagation towards the skin covering, and could be the cause of the superficial hypothermia which is recorded in one third of patients with definite clinical congestion. Hormonal disturbances are observed frequently enough in this syndrome for them to be considered responsible for a large proportion of the congestive and edemaotus phenomena. Observation of these signs enables a choice of therapy to be made, but this is not discussed in this report.

Adult↗

[Ultrasonography investigation of mammary calcifications (author's transl)].

Ultrasonography recordings in 140 patients with breast cancer, 119 with cystic mastopathy, and 299 with benign mammary tumours showed that calcifications are rarely demonstrated, and that diagnosis is not affected to any degree when they are present. Ultrasonography should be used for examination of the breast following the three traditional clinical, radiological, and cytological investigations. False negatives (7.9% of cancers) and false positives (4.2% of fibro-adenomas) are easily corrected from radiological and cytological findings which are still essential for the diagnosis of most mammary affections. Ultrasonography, however, enables an appreciable reduction in biopsy requests to be made in less than 6% of cases of atypical microcalcification in benign mammary lesions.

Breast Diseases↗

[Lactation].

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Breast↗

[Dosage of prolactin in normal and pathological subjects (author's transl)].

Homologous radioimmunoassay of human prolactin was performed and used to investigate the secretion of this pituitary hormone under normal and pathological conditions. The following data were developed in this paper: --During the menstrual cycle, prolactin levels are more elevated during ovulatory and luteal phases than during follicular phase; --During pregnancy, prolactin levels progressively increase to reach their maximum at the end of gestation; --During lactation, prolactin levels increase for the two days following delivery, then progressively decrease; --Bromocryptine oral administration drastically reduces prolactin levels within the 24 hours as it inhibits the prolactin release normally induced by suckling. Assays of prolactin is useful to define the role of this hormone in the genesis of the galactorrhea. Bromocryptine as L Dopa reduce the hyperprolactinemia either functional or tumoral in origin. TRH provokes prolactin release which is more pronounced in females than in males. Pituitary prolactin reserve may be appreciated in several pathological conditions. It appears to be of first interest to assess the residual function of the pituitary gland after surgical removal of adenoma. Depuis 1971, la prolactine humaine peut être dosée dans les milieux biologiques par méthode radio-immunologique (G. BRYANT et coll., 1971; M. L'HERMITTE et coll., 1972; H. FRIESEN et coll., 1972; SINHA et coll., 1973). En 1974 nous avons proposé une méthode de dosage radio-immunologique homologue (A. REUTER et coll., 1976). Grâce à celle-ci nous avons exploré la sécrétion de cette hormone hypophysaire dans certaines conditions normales et pathologiques.

Amenorrhea↗