Search PubMed⌕ Search

Biomedical subjects

C Clerc

Publications and source records attributed to C Clerc.

26 records · Page 2Linked to original sources
PubMed1987

[Use of monoclonal antibodies for the immunoenzymological determination of alpha-fetoprotein in amniotic fluid].

A two site immunoenzymatic assay using monoclonal antibodies for alpha-fetoprotein in amniotic fluid has been evaluated. Results obtained with monoclonal antibodies correlated well with those obtained by electroimmunodiffusion assay. The evaluation of this method has shown rapidity, accuracy and a better sensitivity than electroimmunodiffusion assay. Further more the measurements of both maternal serum and amniotic fluid alpha-fetoprotein can be associated.

Amniotic Fluid↗
PubMed1986

[Use of monoclonal antibodies for the immunoenzyme determination of creatine kinase-isoenzyme MB].

An enzyme immunoassay using monoclonal antibodies for creatine kinase-MB in human serum is described. The specificity and the linearity have been studied. The coefficient of within assay ranges from 6% to 22.5% according to the concentrations. The coefficient of between-assay ranges from 8% to 16.6%. Compared to electrophoresis, the results obtained with the enzyme immunoassay are a better sign of the physical state of the patients.

Antibodies, Monoclonal↗
PubMed1985

[Prenatal diagnosis of abnormalities of the neuroectodermal tube. Limitations of the assay of amniotic alpha fetoprotein and acetylcholinesterase and value of the qualitative study of cholinesterases. Apropos of 6 cases of anencephaly].

Measurement of amniotic fluid alpha-foetoprotein and acetylcholinesterase for the detection of neural tube defects has been used in 285 normal or neural tube defects affected pregnancies: 18 false positive results (with non neural tube defects fetal malformations) have been reported. A qualitative polyacrylamide gel electrophoresis technique has been used to identify the acetylcholinesterase isoenzyme derived from foetal cerebrospinal fluid. Results illustrate the value of amniotic fluid acetylcholinesterase electrophoresis. Amniotic cholinesterase presence may serve as a valuable marker for the detection of neural tube defects.

Acetylcholinesterase↗
PubMed1985

[Amniotic fibronectin in normal pregnancy and pregnancy with fetal anencephaly].

Fibronectin, which is an important protein in plasma and in surface cells was calculated in amniotic fluid using a laser ray nephelemetric technique. In normal pregnancies (in 72 samples studied) this protein which rises towards the 18th week of amenorrhoea (mean +/- S.D.: 60.8 +/- 16.0 mg/l), decreases steadily to term (mean 14.8 +/- 8.9 mg/l). In fetal anencephaly (10 samples tested) high levels were also found but the difference as compared with normal levels was not significant. This measurement does not therefore constitute an extra way of screening for closure of the neural tube.

Amniotic Fluid↗
PubMedDate not supplied

Neointima formation following arterial placement of self-expanding stents of different radial force: experimental results.

PURPOSE: Radial force delivered by self-expanding stents has been discussed as a factor affecting thickness of neointima formation. METHODS: Two types of Wallstents were studied experimentally in vitro and in vivo. Due to an altered braiding angle of the stent filaments, one stent type (LS type) delivers half the radial force to the vascular wall than the conventional type. The radial force was evaluated in a compression-expansion test which related changes in stent length to the compressing force. Fourteen LS and 16 conventional stents were implanted into 15 femoropopliteal arteries of 10 dogs. Autopsy was performed after 4 weeks (14 stents) or 6 months (16 stents). RESULTS: All stents remained patent over the follow-up period with no evidence of stenosis. Neointimal overgrowth was complete and smooth in all. Medial atrophy was a constant finding after placement of both types. Neointimal thickness did not exceed 100 microns after 4 weeks and 6 months and did not significantly differ between LS stents and conventional stents. CONCLUSION: It is concluded that in normal dogs self-expanding stents of the Wallstent type do not induce neointimal buildup that exceeds 100 microns in the femoropopliteal artery. A reduced radial force was not found to result in reduced neointima formation.

Animals↗