Biomedical subjects

C Charousset

Publications and source records attributed to C Charousset.

4 recordsLinked to original sources

PubMed2006

[Arthro-C-scan analysis of rotator cuff tears healing after arthroscopic repair: analysis of predictive factors in a consecutive series of 167 arthroscopic repairs].

PURPOSE OF THE STUDY: Arthroscopic repair of rotator cuff tears is a well described technique with good clinical results. The purpose of this work was to use the arthro-CT-scan to evaluate tendon healing after arthroscopic repair and search for epidemiological, anatomic and technical factors predictive of tendon healing. MATERIAL AND METHOD: This prospective consecutive series included 167 non-randomized shoulders. All patients underwent a preoperative assessment using the crude Constant score and a standard x-ray protocol to evaluate cuff status. Cuff repairs were all performed arthroscopically. The crude Constant score was used to follow patients. A control arthroscan was obtained in 148 patients. RESULTS: Mean patient age was 59 years, 46% men and 77% dominant side. Mean duration of symptoms before repair was nine months. The tears resulted from trauma in 28%, including 9% occupational accidents. The preoperative mean crude Constant score was 52.4 (range 15-77). An isolated tear of the supraspinatus was observed in 68%. Frontal retraction of the supraspinatus was distal in 74%. In 29 cases, reduction was difficult. The quality of the tendon was considered normal in 56 cases and non-anatomic repair was necessary in six. At last follow-up (19 months on average) the mean crude Constant score was 80 (range 49-95). Arthro-CT-scan was performed to control healing in 148 patients and revealed anatomic healing in 69, defective healing in 27, and repeated tears in 52 shoulders. Factors predictive of healing were: tear less than six months old, sedentary occupational activity, non-dominant side, young patient, female gender, isolated small non-retracted tear of the supraspinatus, normal appearance of an easily reduced tendon, and good bone quality. DISCUSSION: Time from tear to repair was long in this series. Tendon and muscle changes occurring after the injury could explain in part the healing failures. CONCLUSION: But this study confirmed good functional and anatomic results given by arthroscopic repair of rotator cuff tears.

Accidents, Occupational↗

PubMed2005

[Not Available].

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Journal Article↗

PubMed2005

Accuracy of CT arthrography in the assessment of tears of the rotator cuff.

CT arthrography and arthroscopy were used to assess tears of the rotator cuff in 259 shoulders. Tear size was determined in the frontal and sagittal planes according to the classification of the French Arthroscopy Society. CT arthrography had a sensitivity of 99% and a specificity of 100% for the diagnosis of tears of supraspinatus. For infraspinatus these figures were 97.44% and 99.52%, respectively and, for subscapularis, 64.71% and 98.17%. For lesions of the long head of the biceps, the sensitivity was 45.76% and the specificity was 99.57%. Our study showed an excellent correlation between CT arthrography and arthroscopy when assessing the extent of a rotator cuff tear. CT arthrography should, therefore, be an indispensable part of pre-operative assessment. It allows determination of whether a tear is reparable (retraction of the tendon and fatty degeneration of the corresponding muscle) and whether this is possible by arthroscopy (degree of tendon retraction and extension to subscapularis).

Adult↗

PubMed2002

[Primary bone lymphoma. Retrospective immunohistochemical study of 22 cases].

PURPOSE OF THE STUDY: The clinical, biological, radiological, MRI, and histological features of 22 primary bone lymphomas were reviewed retrospectively. MATERIAL AND METHODS: The standard pathology slides were reexamined with an immunohistochemistry study. Results of two treatments, chemotherapy alone versus chemotherapy then radiotherapy, were compared in terms of local control and patient survival. RESULTS: Mean age of the patients was 53 years; male gender predominated (M/F=2/1). The most frequent clinical sign was pain and 32% of the patients had a pathological fracture. The long bones were generally involved. The typical radiographic image was a permeable bone defect. MRI demonstrated heterogeneous signals on the T2 images. Technetium scintigraphy (performed in all patients) was very sensitive. Histology generally described diffuse large centroblastic lymphoid cells, all with B phenotype. Twelve patients were treated with chemotherapy alone and eight with chemotherapy and radiotherapy. One patient was only given palliative treatment with corticosteroids due to major immunodepression. The last patient, a 79-year-old woman, developed a tumor of the femoral neck; at surgery section of the neck removed the entire tumor, but radiotherapy (30 Gy) centered on the femur was nevertheless performed. Only patients with fractures were operated. Mean follow-up in this series was 48 months (range 4-120). Mean 5-year Kaplan-Meier survival was 74.41% for the overall series, 83.33% for the chemotherapy group and 82.50% for the chemotherapy-radiotherapy group. DISCUSSION: We were unable to demonstrate any significant difference in survival between the two types of treatment. None of the patients experience local relapse. Our observations suggest that technetium scintigraphy is more sensitive than MRI and more specific for diagnosis. Radiography, together with clinical examination and is indicated to monitor these patients during and after treatment. Based on this series, patients with primary bone lymphoma should be given chemotherapy, either alone or combined with radiotherapy, rather than radiotherapy alone. Surgery is not indicated except to obtain a biopsy and to treat mechanical complications.

Antineoplastic Agents↗