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Biomedical subjects

C Carrillo

Publications and source records attributed to C Carrillo.

84 records · Page 5Linked to original sources

Clinical effectiveness of "short" vs "long" psychiatric hospitalization. I. Inpatient results.

To evaluate the clinical effectiveness of short-term (three month maximum length of stay) and long-term (discharge based on clinical judgement) hospitalization, the inhospital course of 68 "short-" and 58 "long-term" psychiatric patients was studied. The results indicate that patients assigned without bias to short-term patterns, however, indicated that these results could be entirely accounted for by the significantly greater use of group therapy as an additional treatment modality in the short-term units. The need for a more systematic exploration of the effect of restricted hospital stay on the treatment patterns of the clinician and the effect of these differential treatment patterns on inhospital improvement is emphasized. The necessity for follow-up data to gain a complete picture of these treatment contrasts is clear.

Adolescent↗

Fecal microflora in health persons in a preindustrial region.

Procedures for quantitating the fecal microflora of man were described. Special attention was given to criteria for characterizing the culturable aerobic, Micro-aerophilic, and anaerobic bacteria. Three groups of healthy persons were studied: wholly breast-fed infants (2 to 4 month-olds), weanlings (1 to 2 year-olds), and adults. In breast-fed children, bifidobacteria predominate and outnumber by one or several logs all other culturable bacteria. The fecal flora of wholly breast-fed infants is "simpler" and more numerous [10(11) to 10(12) per g (wet weight) of feces than that of the adult 10(2) to 10(11) per g]. In the adult, gram-negative anaerobic bacilli (bacteroides) outnumber all other groups by a factor of 1 log or more. Weanlings receiving an adult-type diet, but still breast-fed, showed a flora intermediate between that of the wholly breast-fed infant and that of the adult, but more similar to the latter. Anaerobes always constitute the predominant component of the culturable flora of children and adults and are always found in large numbers under conditions of health. The aerobes are significantly less numerous, and vary widely in their number and in the frequency with which they appear in feces.

Adult↗

Initial steps of wall protoplast regeneration in Candida albicans.

Cell wall regeneration of individual Candida albicans yeast and mycelial protoplasts was studied with confocal and electron microscopy using polyclonal antibodies and lectins. Quantitative measurements of the fluorescence emitted by individual protoplasts during the process of regeneration indicate that chitin is the first polymer to be laid down, whereas beta (1,3)- and beta (1,6)glucan are incorporated at a later stage. Mannoproteins were found on the surface of fresh protoplasts and those newly synthesized were then deposited with time. During the first steps of wall regeneration, the proteins that interacted covalently with chitin or glucan were different, but the same species were found linked to each polymer in yeast and mycelial regenerating forms. The aggregates formed by regenerating protoplasts were shown to be due to the chitin and mannoprotein network initially laid.

Blotting, Western↗

Acidic ribosomal proteins and histone H3 from Leishmania present a high rate of divergence.

Another additional peculiarity in Leishmania will be discussed about of the amino acid divergence rate of three structural proteins: acidic ribosomal P1 and P2b proteins, and histone H3 by using multiple sequence alignment and dendrograms. These structural proteins present a high rate of divergence regarding to their homologous protein in Trypanosoma cruzi. At this regard, L. (V.) peruviana P1 and T. cruzi P1 showed 57.4% of divergence rate. Likewise, L. (V.) braziliensis histone H3 and acidic ribosomal P2 protein exhibited 31.8% and 41.7% respectively of rate of divergence in comparison with their homologous in T. cruzi.

Amino Acids↗

Humoral immune abnormalities in human brucellosis.

Humoral immune responses were evaluated in a group of patients with acute brucellosis due to Brucella melitensis biotype I. Levels of immunoglobulins, C3 and C4, and the presence of antinuclear antibodies, rheumatoid factor and circulating immune complexes were sequentially studied in all brucellosis patients during the acute phase of the disease and following specific therapy. Elevated levels of all immunoglobulin classes, IgG, IgM and IgA and C3, C4, were found in the majority of patients. Antinuclear antibodies, rheumatoid factor and circulating immune complexes were found in circulation, particularly during the active stages. These findings provide support for the participation of the humoral immune system in the pathogenesis of human brucellosis.

Adolescent↗

Reactive arthritis associated with brucellosis: HLA studies.

HLA typing studies were performed on a group of 16 patients with acute Brucella-induced reactive arthritis and results were compared to those obtained in 16 patients with acute brucellosis but without arthritis and to 55 normal control subjects. No increased prevalence of any HLA antigen was noted between patients and control groups. HLA-B27 frequency was diminished in the Peruvian population studied. The most interesting finding was the presence of a statistically significant low frequency of HLA-A2 in the disease group suggesting that this antigen may play a protective role for the development of brucellosis.

Adolescent↗

[Mortality by poisoning in children].

OBJECTIVE: To determine the standing of mortality by poisoning in children in the Mexican Republic, in the years from 1979-1994. MATERIAL AND METHODS: Secondary sources were employed. Analyzed variables were: age, sex, year, external cause of trauma and poisoning according to the 9th International Classification of Diseases: E850-E858, E860-E869 and E905. Tendencies by specific causes were analyzed with a Poisson regression model and relative risk by age, sex and district were obtained. RESULTS: A total of 11,272 children under 15 years of age were recorded. The main causes were poisoning and toxic reactions caused by venomous plants or animals (E905); accidental poisoning by household gas or carbon monoxide (E868); and accidental poisoning by other drugs (E858). The relative risk was highest in age group < 1 year; the values were RR 29.6, CI 95% 29.2-33.4; RR 3.47, CI 95% 2.86-4.22 and RR 31.86, CI 95% 24.8-40.9. Risk was similar for both sexes except for E905. The state of Aguascalientes consistently presented the highest risk values and the state of Nuevo Leon, the lowest. CONCLUSIONS: Poisoning is an important cause of child mortality. Considering that most of these deaths can potentially be prevented since they occur at home it is recommended that responsible adults can build protection into their environment and into the way society operates. Prevention should involve a multidisciplinary approach since the phenomenon has multiple causes and possible solutions.

Cause of Death↗