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Biomedical subjects

C Caron

Publications and source records attributed to C Caron.

125 records · Page 7Linked to original sources

[Potomania: re-evaluation of the diagnostic tests and unusual presentation with hydronephrosis and megabladder].

Three cases of compulsive polydipsia previously diagnosed as diabetes insipidus are presented. Abnormally dilated bladder and pyelocalyceal systems were accompanying features, as previously described for diabetes insipidus, particularly of renal orign. Results of the hypertonic saline (Hickey-Hare) test were positive in only one case. Results of restriction of liquids followed by intravenous injection of vasopressin (Miller test) favoured a diagnosis of complete diabetes insipidus. These two tests cannot, therefore, exclude compulsive polydipsia. The features suggesting a diagnosis of compulsive water drinking are low plasma osmolality, a decrease in 24-hour urine output following water restriction, and abnormal behaviour. The diagnosis is confirmed by an 18-hour dehydration test done after gradual fluid restriction, which favours partial restoration of the papillary osmotic gradient.

Adolescent↗

[Digitalis].

Explore the source record for details and available documents.

Digitalis Glycosides↗

[Esophageal angina: detection by esophageal manometry with the methylergometrin maleate test].

The purpose of this study was to assess the value of methylergonovine maleate administration as challenge test for abnormal oesophageal contractions. Manometric exploration of the oesophagus was performed before and after administration of methylergonovine maleate 0.4 mg in 28 patients suffering from retrosternal pain of proven extracardiac origin. Six patients had unexplainably suffered when receiving the drug during coronary arteriography (group A), while 22 had experienced no pain (group B). A group of 7 control subjects were explored at the same time and with the same procedure (group C). Methylergonovine maleate produced painful oesophageal abnormal contractions in 5 of the 6 patients in group A. The 6th patient in this group and 2 patients in group B had abnormal contractions without pain. Another group B patient developed coronary arterial spasm reversed by sublingual nitroglycerin. In the 2 group A patients who received nitroglycerin, the drug rapidly relieved the retrosternal pain and the abnormal contractions induced by methylergonovine maleate. This study demonstrates the value of oesophageal manometry with methylergonovine maleate test in patients with anginal pain but normal coronary arteriography. It also highlights the need for continuous ECG monitoring during the test, even when the patients had responded negatively to methylergonovine maleate during coronary arteriography.

Esophageal Diseases↗

Implementing nursing diagnoses within the context of King's conceptual framework.

The use of nursing conceptual frameworks and nursing diagnoses is generally acknowledged to hold immense promise for the further development of nursing's scientific base. The nursing profession to date has failed to link the two, thus diminishing their impact. A large community hospital in Canada adopted King's Conceptual Framework for Nursing Practice and advocated the use of NANDA's nursing diagnostic statements as the manner by which patient needs or problems would be identified. Nurses, however, required assistance in identifying more clearly the connection between the theoretical base and nursing diagnoses. During stage one of this project a tool was designed that categorized NANDA's nursing diagnoses according to the concepts and systems of King's conceptual framework. The difficulties encountered in categorizing the nursing diagnoses are discussed and the categorization system is outlined. The utility of the tool was tested during stage two. A total of 25 nurses were asked to describe how they arrived at a particular nursing diagnosis before and after using the categorization tool. Criteria were used to indicate whether a connection had been made between the formulation of the nursing diagnosis and King's conceptual framework throughout the nurse's thought processes. The results indicated that nurses could make a connection between NANDA's nursing diagnoses and King's framework with the assistance of the categorization tool.

Classification↗

Modification of RBC properties by an autoantibody. Binding to RBC senescent antigen.

It has been reported that natural antibodies alter aging RBCs, so increasing their vulnerability for removal from the blood stream. Results presented indicate that binding of anti-Gal, a natural antibody, to erythrocytes increases RBC rigidity in terms of microviscosity and deformability. Removal of RBCs from circulation could, at least in part, depend on these alterations.

Antigen-Antibody Complex↗