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Biomedical subjects

C Carenfelt

Publications and source records attributed to C Carenfelt.

At least 37 records · Page 2Linked to original sources
PubMed1989

Test-retest reliability of the nasopharyngeal culture in children.

Aspects of test-retest reliability of the nasopharyngeal culture were evaluated in children with otitis media and in ear, nose and throat (ENT)-healthy children, in all 174 cases. The nasopharyngeal colonization of Streptococcus pneumoniae, Haemophilus influenzae, Branhamella catarrhalis and beta-haemolytic streptococci was determined for a group of children with well-defined otitis media effusion (OME). The valitity of the results was then tested in a new group of children with OME. Despite seasonal differences and different bacteriologists analysing the specimens, high conformity was found between the two groups regarding distribution and recovery rates of the potential pathogens studied. The test-retest reliability of the culture was also analysed by duplicate specimens in children with acute otitis media (AOM), OME and in ENT-healthy children. The reproducibility of the findings of pathogens, whether quantitative aspects were considered or not, was found to be between 70 and 80% for children with AOM and OME.

Bacteria↗
PubMed1989

Etiology of acute infectious epiglottitis in adults: septic vs. local infection.

Adult patients with acute epiglottitis hospitalized between 1975 and 1988 were retrospectively analysed. 79 of 138 patients had a valid diagnosis and had delivered at least one blood culture and were considered eligible for further evaluation. Cultures from the upper airways, including epiglottis, were available in 43 of the patients as a consequence of prospective measures. 27% of the patients had bacteremia, which may however be an overestimation. Haemophilus influenzae was the predominating finding, but Streptococcus pneumoniae was isolated from 3 severely ill patients, indicating the existence of pneumococcal epiglottitis at a rate of less than 5%. From the non-bacteremic patients with a localized disease, either H. influenzae or beta-hemolytic streptococci were isolated from the epiglottis in one third of the cases. The distribution of pathogens in upper airways indicates that beta-hemolytic streptococci may have an etiological role in acute infectious epiglottitis. Except for H. influenzae, species with the potential ability of beta-lactamase production have no significance in the disease.

Acute Disease↗
PubMed1988

Origin of the choanal polyp.

To study the origin of the choanal polyp, the maxillary sinus was surgically explored using a preservative technique. An antral cyst or a cystic rudiment, usually attached to the inferolateral aspect of the sinus wall, was disclosed in 15 patients with this condition. As a part of the choanal polyp, the antral cyst exhibited a macroarchitecture and microarchitecture identical to the structure of the common intramural cyst of the maxillary sinus as studied in nine patients. It is concluded that the choanal polyp develops from the expanding intramural cyst protruding through the maxillary ostium and into the nasal cavity.

Adult↗
PubMed1988

Bacteriology of maxillary sinusitis in relation to character of inflammation and prior treatment.

By antral aspiration, 200 sinus secretions were obtained from the same number of adult patients with maxillary sinusitis. The bacteriological findings were related to the character of the secretions as well as to the duration of symptoms, previous antibacterial treatment and possible dental genesis. Pathogens were isolated in 87% of 54 patients with untreated acute sinus empyema, Streptococcus pneumoniae being the most prevalent (57%). In 47 cases of treatment failure Haemophilus influenzae predominated and was found in 60% of the purulent secretions. In all, 11% of the 47 cases showed growth of beta-lactamase-producing H. influenzae, corresponding to 18% of all H. influenzae in this group. Staphylococcus aureus and anaerobic bacteria were infrequent findings except in purulent sinus secretion from patients with a long history. In contrast to patients with sinus empyema, no pathogens were found in the majority of 37 patients with non-purulent sinusitis.

Adolescent↗
PubMed1985

Etiological diagnosis in sinusitis: ultrasonography as clinical complement.

Accumulation of purulent sinus secretion reflects an inflammation caused by pyogenic bacteria, whereas the accumulation of nonpurulent effusion may have origins other than a bacterial infection. Ultrasonography differentiates the disordered sinus from the healthy one, but not purulent from nonpurulent secretion. In 90 patients, supposed to suffer from sinusitis, a correct diagnosis, sinus empyema vs. not sinus empyema, was established in a majority of cases by means of clinical evaluation alone. By introducing ultrasonography as a complement to the clinical evaluation, the diagnostic reliability became lower. It is concluded that ultrasonography seems to have little or no implication in the therapeutic decision unless diagnostic puncture is also performed.

Adolescent↗
PubMed1983

Permanent indwelling tubes in benign oesophageal stricture.

Permanent intubation of benign oesophageal stricture seems to be rather frequently used, but there are few reports on indications and results. The limited experience from 9 intubations in 7 patients presented, is not encouraging. Massive gastro-intestinal bleeding, peptic reflux and tube migration were seen, and 4 of the tubes had to be sacrificed within 6 weeks. Two patients only had full and lasting benefit of the treatment without serious tube complication. Indwelling tubes should be considered in benign strictures only as an alternative to gastrostomy, particularly in those patients feeling strong aversion to permanent stomy.

Aged↗
PubMed1982

Antral aspiration.

In sinus research, aspirated undiluted antral secretion has long been used for quantitative analysis. The antral aspiration technique described here is also a convenient method in diagnostic and therapeutic routine. Compared with antral irrigation, the aspiration technique provides a more detailed picture of the sinus state, which can facilitate further management of the sinusitis.

Humans↗
PubMed1980

Facial bone scintigraphy. VI. Practical clinical use in inflammatory disorders of the maxillary sinus.

Facial bone scintigraphy with 99Tcm-DP was compared with radiographic examination of the maxillary sinuses in a clinical routine series of patients considered to have inflammatory disorders of the maxillary sinus. Scintigraphy correlated better to the presence of purulent inflammatory lesion than did radiography. Bone tissue reaction is almost mandatory for the diagnosis of purulent maxillary inflammatory disorder.

Adolescent↗
PubMed1979

Facial bone scintigraphy. V. Differentiation of purulent from non-purulent inflammation of the maxillary sinus.

In a series of 25 patients 20 had a maxillary sinus not containing air at radiography, in 11 due to purulent and in 9 to non-purulent inflammatory lesion. At scintigraphy a definitely abnormal, high uptake of 99TcmDP was found in 10 and a probably high accumulation in one of the 11 with purulent sinuitis. Of the 9 patients with non-purulent inflammation 5 had a definitely normal and 4 a probably normal uptake. Thus, a differentiation between purulent and non-purulent sinuitis would seem to be possible by means of facial bone scintigraphy.

Humans↗
PubMed1979

Anaerobic bacteria in maxillary sinusitis.

The anaerobic bacterial flora of purulent maxillary sinusitis was investigated in 30 patients and the different anaerobic species identified and tested with respect to antibiotic susceptibility. Most strains were identified as anaerobic cocci. Non-sporeforming Gram-positive rods and Gram-negative rods other than Bacteroides fragilis were also isolated. The majority of the strains were susceptible to benzylpenicillin, cefoxitin, clindamycin, doxycycline, metronidazole and chloramphenicol.

Anti-Bacterial Agents↗
PubMed1977

Pneumococcal antibodies in maxillary sinus secretion.

Resistance to and recovery from mucosal surface infections may be better correlated to the presence of local antibodies than to serum antibodies. In 14 patients with maxillary sinusitis due to pneumococci, IgA, IgG and IgM antibodies to the isolated pneumococci were quantified in sinus secretion and serum by indirect immunofluorescence technique. Most secretions contained type specific pneumococcal antibodies, mainly of IgA class. The frequent lack of demonstrable type specific IgA antibodies in serum indicates their local synthesis. After drainage of purulent sinus secretion, as in 5 patients, a local increase of antibodies was observed.

Adult↗