[Aorto-coronary bridging associated with aortic valve replacement. With reference to 14 cases (author's transl)].
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Biomedical subjects
Publications and source records attributed to C Cabrol.
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Report of one case of a Laubry and Pezzi syndrome. In spite of the already severe aortic incompetence at the age of 4 years, operation was postponed. Three years later, at the first signs of bad tolerance of the aortic incompetence the operation was undertaken including: -- closure of the ventricular septal defect by a patch, and correction of aortic incompetence by a metallic-ball Starr's prosthesis n 9. After an observation period of 18 months, the result of operation is satisfactory, in spite of signs of haemolysis. Comparison with the data from the literature led to the following conclusions: 1) in a patient with ventricular septal defect the demonstration of a diastolic murmur indicates closure of the septal defect. 2) When the aortic incompetence is a severe one, it should be corrected urgently, whatever the age of the child, if badly tolerated. In the very young child, if it is well tolerated, the operation might be postponed in view of the difficulties of plastic operations and the hazards of prostheses in such patients. 3) A moderate aortic incompetence constitutes the most difficult indication; a conservative operation seems to be preferable to a valve replacement by a prosthesis, a homograft or a heterograft. The results obtained by some techniques of valvular plasty after observation periods amounting to 12 years are considerable.
Intraventricular reentry has been prooved by pre-operative electrophysiological studies in two patients without coronary artery disease and resistant ventricular tachycardia. A simple ventriculotomy oriented by epicardial mapping during tachycardia was successfull with a background of 9 and 14 months respectively. In addition, delayed epicardial potentials put into evidence an intraventricular reentry in human myocardium. This new method holds promises for the treatment of some resistant ventricular tachycardia.
One case followedup for 7 years with progressive intensification of regurgitation, requiring a surgical operation at the age of 48 years, brings its contribution to knowledge of the natural history of late systolic mitral incompetence and of the anatomical lesions causing it. The presence of prolapsed posterior leaflet, of stretched chordae tendinae, of both septal and parietal muscle hypertrophy with biloculation of the ventricular cavity were suggested by angiocardiography and confirmed by operation. A review of the literature reporting the cases with operative or post-mortem verification poses the unresolved question of the diagnostic criteria of late systolic mitral incompetence at the stage of cardiac failure.
Analysis of a series of 10 cardiac transplantations confirmed that the reject phenomena have a paroxysmal course, the diagnosis of which is different according to the time occurence of the reject crises, whether early (acute early rejection) or late (late acute rejection or chronic rejection). Because of the early diagnosis based on the follow-up of the electrocardiogram, of coagulation, of the graft flow, overcome eight rejection crises on the 3 patients with middle-term survival.
Out of 400 files of patients who underwent valvar correction between 1968 and 1974 under extra corporeal circulation by the thoracic route through median sternotomy 180 were kept for this study. All these 180 patients had a complete functional spirometric examination before operation, analysed in correlation with their valve disease. 39 of them had severe ventilatory insufficiency. Nevertheless the post-operative period was usually simple, and respiratory insufficiency was responsible for one death only of this series. These data were confirmed by the study of 45 autopsied patients who died after operation. At distance from operation, 80 patients were studied, 25 of whom had severe ventilatory insufficiency. In more than half the cases, and particularly in the mitral ones, the ventilatory deficiency was improved. Thus it is concluded that, respiratory insufficiency is rarely a contra-indication to valve replacement surgery in habitual conditions of the median sternotomy as a thoracic route.
Six cases of post-embolic chronic cor pulmonale are presented. All six were treated with thrombolytic agents (4 with streptokinase, 2 with urokinase), and in only one case was improvement maintained at the end of one year. Two patients underwent a disobliterative procedure of the pulmonary artery, together with ligation of the inferior vena cava. One of these operations was unsuccessful, and the other had a successful outcome, as confirmed by objective assessment with angiography, scintigraphy and haemodynamic studies. The literature is reviewed at this stage. It was found that the fibrinolytic agents had some chance of working only if the condition was less than a few months old. One major drawback to surgical disobliteration that cannot be foreseen before operation is the presence of thromboses at the arteriolar level in subjects whose main arteries are already blocked proximally. Nervertheless it is possible to obtain good results by surgery, and the operation is worth attempting in young subjects, given the poor prognosis of the untreated condition.
A recent personal study of the coronary arteries has enabled us to give precise details of the blood supply of the nodal structures. The right coronary artery is the commonest source (supplying 67% of the sino-atrial nodes, 85% of the atrio-ventricular nodes, and both nodes simultaneously in 60%). During the course of this study we have also demonstrated that the sino-atrial node may have a double vascular supply. It seems likely that the blood supply to the atrio-ventricular node is complex; because of the limitations of our study method, we examined only the main source of supply.
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In a 53-years old patient complaining of dyspnoea and angina of effort, the coronary arteriography demonstrated ab abnormal implantation of the pulmonary artery into the left coronary-artery. Correlated with the 39 cases of the adolescent and the adult published in the literature, the case reported has some peculiarities: poorness of the auscultatory signs consisting in a mild apical systolic murmur; electrocardiographic pattern of left complete bundle-branch block; presence of massive calcifications visible by X-ray into the lateral, wall of the left ventricle. Coronary arteriography and catherization made it possible to demonstrate a left-to-right shunt by backward-flow revascularization of the left coronary artery starting from the right coronary artery. A simple suture of the implantation foramen of the abnomal coronary artery resulted in increased pressure into this artery and was followed by disappearance of angina during an observation period of 5 months.