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Biomedical subjects

C Cabrol

Publications and source records attributed to C Cabrol.

At least 235 records · Page 13Linked to original sources
PubMed1983

Isochromosome 21 and other chromosomal abnormalities in a patient with erythroleukaemia.

Cytogenetic analysis in a patient with erythroleukaemia revealed a hypodiploid cellular clone with several acquired karyotypic aberrations including an isochromosome for the long arm of chromosome 21 : 45,XY,-5,-7,-18,-19,-21, + 17, + i (21q)(qter leads to cen leads to qter), + mar1, + mar2. The markers probably include respectively the major part of chromosome 19 and most of the long arm of chromosome 7. These rearrangements and their potential significance are discussed.

Aged↗
PubMed1983

[Anatomic study of the left inferior diaphragmatic vein (vena phrenica inferior sinistra)].

The anatomy of the left inferior phrenic vein is poorly understood. It can be exposed by transecting the left triangular ligament and clearing the hepatic veins. We inspected twenty embalmed specimens that were injected with Rhodorsil. Generally, the vein has its origin above the diaphragm near the apex of the heart. After traversing the diaphragm, the vein receives two collateral veins, in front of the left triangular ligament. One is located anteriorly and to the right of the vein, the other one is situated behind and to the left. The phrenic vein continues laterally, passing posteriorly to the triangular ligament, or rarely, when the coronary ligamentum is wider than usual, the vein will pass through it as well. In 74% of the case, the vein terminates into the left side of the left hepatic vein. Three dissections appeared to be very interesting: --in one, the vein followed the free margin, then the hepatic margin of the triangular ligament, receiving accessory hepatic veins, --in another, the vein joined the right inferior phrenic vein in front of the inferior vena cava, --in the third one, the vein followed the left inferior phrenic artery, to join the left suprarenal vein, then terminating in the left renal vein.

Adult↗
PubMed1983

[Myxoma of the left atrium and advanced renal failure].

A 34 years old woman with a history of childhood rheumatic fever presented with a number of episodes of systemic embolism over a 10 years period attributed to mitral stenosis despite long-term anticoagulant therapy. All preoperative electrocardiograms showed sinus rhythm. After one episode of recurrent embolism (brain, limbs) requiring femoral embolectomy, she developed oligo-anuric renal failure and needed 21 days of hemodialysis. She made a full recovery. Several years later, she presented with chronic progressive renal failure. The diagnosis of left atrial myxoma was eventually made at echocardiography: surgical excision was successful. Periodic hemodialysis was started six months later. The authors use this case to illustrate unusual presentations of myxoma and above all their vascular complications; the possibility of embolic renal disease leading to advanced renal failure is discussed, a complication of left atrial myxoma which seems to be very rare.

Adult↗
PubMed1983

Open heart surgery in patients with end-stage renal disease.

Seventeen patients on maintenance dialysis therapy or with severe impaired kidney function required correction of cardiovascular diseases by open heart surgery. Ten aortic, two mitral valvular replacements and five coronary artery bypass grafts were performed. Special attention was taken for these patients, including pre-operative dialysis, cardiopulmonary bypass with complete haemodilution, composition of extracorporeal circuit volumes, arterial and venous access and myocardial protection. Prosthetic valves were preferred to porcine heterografts for valve replacements and autogenous saphenous veins were utilised for coronary artery bypass grafts. Follow-up of 14 patients was available from one to 84 months. Carefully planned open heart surgery can be successfully carried out in uraemic patients without an increased operative risk.

Adult↗
PubMed1983

[Morphometric study of the piririform aperture].

The piriform aperture or enter orifice of the nose may be too small, creating an obstacle for inspirated flow. The functional disturbance realised has been described as the "syndrome of aspiration of the nasal ala". The present study has been made on 100 skulls. We have measured the dimensions of the piriform aperture, calculated a "form index" and searched a correlation between the morphology of this aperture and the morphology of the skull. It appears that the form and the dimensions of the piriform aperture depend on the ethnic origin and not on the cranial anthropologic type. The surface of the piriform aperture can be calculated on a radiological examination. The dimensions and the form of the piriform aperture must be correlated with the morphology of the nasal pyramid. Knowledge of the dimensions of the piriform aperture is useful for diagnosis of functional rhinologic disturbances.

Anthropology, Physical↗
PubMed1983

[Diagnosis of restrictive cardiomyopathy in the hypereosinophilia syndrome by 2-dimensional echocardiography].

The cardiac manifestation of the hypereosinophilic syndrome was diagnosed by means of echocardiography in a 36-year-old man. The following two-dimensional echocardiographic characteristics indicated a restrictive cardiomyopathy in this patient: Enlargement of the left atrium. Thrombotic obliteration of the left ventricle from the apex up to the subvalvular region. Embedding of the chordae tendineae and papillary muscles by the thrombotic mass. Normal left ventricular ejection fraction. The echocardiographic findings were verified by autopsy.

Adult↗
PubMed1982

Clones with 3 Ph1 and 4 Ph1 in the terminal phase of three cases of chronic myeloid leukemia.

G-banded cytogenetic studies of 3 male patients in the terminal phase of chronic myeloid leukemia showed the following abnormalities: in the first case, the presence of a medullar cell line with 51 chromosomes and 3 Ph1; in the second case, a clone with 65 chromosomes and 4 Ph1, and in the third patient a clone with 53 chromosomes and 3 Ph1. In all 3 cases, G-banding revealed the Ph1 translocation to be of the usual type: t(9;22) (q34;q11) and there was discordance between the number of Ph1 and 9q+. There was no obvious correlation between the presence of multiple Ph1 and the clinical or cytological features. These 3 cases were detected as part of a recent G-banded cytogenetic survey of 9 individuals in the blastic phase studied by the authors. The frequency of multiple Ph1 observed in this sample of blastic-phase leukemia is unusually elevated, raising the question of the origin of such a high incidence.

Adult↗
PubMed1982

[Abnormal communications in acute bacterial endocarditis of the aortic valve].

Abnormal communications acquired during acute aortic valve bacterial endocarditis are rare but serious complications. Seven cases are reported; between the left ventricle and right atrium (3 cases), the left and right ventricles (2 cases), the aorta and right atrium (I case) and the aorta and left atrium (I case). The usual causal organisms is a staphylococcus (4 out of 7). The diagnosis is suspected on the development of atrio-ventricular block, a parasystolic murmur and sudden severe cardiac failure, but can only be confirmed by catheterisation and angiocardiography (impractical in our patients because of their poor condition). Echocardiography is of great diagnostic value. Surgical cure involves a double approach aortotomy and opening the other chamber involved), with extensive excision of the infected tissues, closure of the perforation, reconstruction of the aortic ring and implantation of an aortic valve prosthesis. The extent of the anatomical lesions affects the choice of the mode of reparation. There was no operative mortality in our series but two patients have persistent diastolic murmurs due to perivalvular leaks. In one case, recurrent infection led to the implantation of an apico-aortic tube with a fatal outcome.

Adult↗
PubMed1982

[Encircling endocardial ventriculotomy in the treatment of recurrent ventricular tachycardia after myocardial infarction].

Thirty nine men and two women aged 26 to 76 years old (average 55 years) with ventricular tachycardia (VT) complicating chronic myocardial infarction were operated on between December 1971 and September 1980. Epicardial mapping was performed in sinus rhythm in 25 cases and in VT in 12 cases. The series was divided into two consecutive groups: --The first group comprised 14 patients operated on between December 1971 and November 1975 in which the operative mortality at the 30th day was 36%. There was one death due to recurrent VT in the early post-operative period; two deaths due to arrhythmia were observed between the 11th and 26th postoperative months. VT was successfully prevented in 6 cases with over 2 years' follow-up. --The second group comprised 27 patients operated after November 1975, in which encircling endocardial ventriculotomy (EEV) was the procedure used. The operative mortality fell to 18% with no relation to the arrhythmia. In the first 10 cases of this group, VT recurred in 2 patients in the early postoperative period. These two cases were controlled with antiarrhythmic therapy at doses that had been ineffective preoperatively. Four other recurrences of VT were observed at the 3rd, 34th, 45th, and 56th postoperative months. They were controlled by anti arrhythmic agents in 3 cases. The other patient died. VT was prevented for over 2 years in 7 patients and for over I year in 16 patients. These results suggest that EEV is more effective than the techniques used previously in resistant VT. Its side effects on myocardial contractility are discussed.

Adult↗
PubMed1982

[Thermal isolation of the heart by means of a plastic foam pad during surgical cooling of the heart: experimental study].

Maintenance of myocardial cooling during aortic clamping is a problem encountered currently during heart surgery. A plastic foam isolation pad was studied. Eight animals (pigs weighing 50 kg) were placed on extracorporeal circulation, 4 of them constituting the control group (A). Two coronary injections of a cardioplegic solutions were administered, the first at the time of aortic clamping and the second 30 minutes later. The myocardium of the 4 animals in the treated group (B) was isolated with the foam pad, and this significantly prolonged the "cold" effect of the cardioplegic. Ten minutes after injection of the cardioplegic, temperature of the total myocardial mass with isolation was between 10.7 and 12 degrees C, as against 16 to 18 degrees C in the reference group (p less than 0.05). By the 20th minute, the isolated myocardium was at approximately 15 degrees C as against 22 degrees C in group A (p less than 0.01). Finally, by the 30th minute, temperature in group B was 17 degrees C as against 23 degrees C in group A (p less than 0.01). Reheating of the heart was significantly slowed by thermal isolation, though the limit of 15 degrees C was reached by the 20th minute. To ensure that myocardial temperature remains below this limit when the foam pad is employed, further injections of cardioplegic solutions are necessary every 20 minutes.

Cardiac Surgical Procedures↗