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Biomedical subjects

C C Winter

Publications and source records attributed to C C Winter.

At least 55 records · Page 3Linked to original sources

Priapism: evolution of management in 48 patients in a 22-year series.

The choice of an effective method to treat priapism is challenging because precise causes in the majority of patients have not been well defined. A review of 48 patients treated during a 22-year period shows evolution of a regimen of management that has yielded a high percentage of success. Idiopathic priapism and sickle cell disease accounted for 81 per cent of the subjects. An evaluation should include a medication history, a search for specific diseases, as well as a thorough physical examination to detect possible etiologic factors. The explanation for the frequent association of fever deserves further investigation. Initial therapy consisting of aspiration and irrigation, and intermittent pneumatic cuff compression should be undertaken for a trial period of 12 to 36 hours, repeating the aspiration 2 or 3 times if necessary. The failure of priapism to resolve after such treatment is an indication for a shunt operation. Patients with known etiology should be treated specifically for the primary disease and usually more conservatively for priapism. Resolution occurred in all patients and approximately 50 per cent regained sexual potency.

Adolescent↗

Unilateral and bilateral bladder neck suspension (modified Pereyra) operation for stress urinary incontinence.

Stress urinary incontinence can be corrected by a short, simple, minor suturing technique, a modification of the Pereyra operation. Success depends upon careful selection of patients, the proper tightness of the suture over a proper-size catheter and the use of intermittent endoscopy during the operation. Successful outcome up to 7 months has been achieved in 7 of the 8 patients but reoperation was necessary for the successful outcome in 1 of the 2 failures.

Adult↗

Long-term results of cutaneous omento-ureterostomy.

Six of 11 patients have had 2 to 7 1/2 years of followup evaluation after cutaneous omento-ureterostomy. Results were excellent in 3 cases and good in 1, while ureteral stomal stenosis developed in the 2 patients irradiated for bladder cancer. Complete prevention of cutaneous ureterostomy stoma stenosis remains unachieved but the use of a plastic meatal dilator seems useful.

Adolescent↗

Anterior transposition of urethra.

The case reports of 3 patients who underwent anterior transposition of the urethra are presented. Our modification is believed to shorten the operative procedure and to be equally satisfactory compared to the results presented by previous urologic surgeons. We join those who recommend this operation in the thin female patient who has a neurogenic bladder with constant leakage around the indwelling urethral catheter despite use of larger size tubes.

Abdominal Muscles↗

Rapid miniaturized tests for bacteriuria: Microstix and bacturcult urine tests.

Of 4 methods for testing random urine samples for the presence of infection the standard hospital laboratory culture-colony counting was found by far to be the most accurate. Microscopy of urinary sediment, Microstix and Bacturcult produced too many falsely negative results to be useful in a clinical setting, were urine samples were collected throughout the day such as in an office or hospital outpatient clinic. Perhaps the last 2 tests would yield better results if urine samples were collected after at least 4 hours of incubation time in the bladder, as suggested by their proponents.

Bacteriological Techniques↗

Peyronie's disease: results with dermo-jet injection of dexamethasone.

The results in 21 patients with Peyronie's disease who were managed with a course of dermo-jet percutaneous injections of dexamethasone into the plaques are described herein. These patients had 6 to 10 injections at intervals of 1 month for 6 months. In a high percentage of the cases there occurred a disappearance or decrease in the size of the plaques, pain on erection and discomfort during sexual relations. Also, there was a high rate of improvement in the chordee. Because of the natural history of resolution of the plaques and the small number of patients, statistical significance is not believed applicable, although 71 per cent of the patients had experienced prior failure with other modes of therapy. Eight patients experienced urinary or prostato-epididymal infections at some time in their medical history, correlating well with the inflammatory theory as the cause of the disorder.

Adult↗

Long-term results of cutaneous omento-ureterostomy.

Six of 11 patients have had 2 to 7 1/2 years followup evaluation after cutaneous omento-ureterostomy. Results were excellent in 3 cases and good in 1, while ureteral stomal stenosis developed in the 2 patients irradiated for bladder cancer. Complete prevention of cutaneous ureterostomy stoma stenosis remains unachieved but the use of a plastic meatal dilator seems useful.

Adolescent↗