Biomedical subjects

C C Huang

Publications and source records attributed to C C Huang.

At least 37 records · Page 2Linked to original sources

PubMed2004

Optical investigations on the biaxial smectic- A phase of a bent-core compound.

Several unique optical properties have been obtained from freestanding films of a bent-core compound. Our experimental results indicate the existence of the antiferroelectric biaxial smectic-A (Sm A) phase. The critical exponent associated with the biaxiality through the uniaxial-antiferroelectric biaxial Sm A transition has been measured to be 0.82+/-0.04 , which is in good agreement with our theoretical calculation. Our theoretical advances further demonstrate that the critical behavior of the optical biaxiality with the order parameter being a vector is described by the secondary-order parameter of the three-dimensional XY model. We also observe a remarkable even-odd layering effect exhibited by the surface layers of freestanding films under an applied electric field (approximately 20 V/cm) in the film plane.

Journal Article↗

PubMed2004

Major brain lesions detected on sonographic screening of apparently normal term neonates.

Major congenital or acquired structural abnormalities of the brain, with significant prognostic implications have rarely been emphasised in apparently normal infants. Our purpose was to investigate the prevalence and types of major brain lesions in clinically normal term neonates using sonography. From January 1999 to December 2001, we examined 2309 clinically normal term neonates within 3 days of birth. Of these, six (0.26%) had major brain lesions, including three cases of intracerebral haemorrhage (two grade II intraventricular and one temporal lobe haemorrhage), two of corpus callosum agenesis and one lacunar infarct in the territory of the left middle cerebral artery. One child was lost to follow-up, because of adoption, and four had borderline to significant developmental delay at a mean age of 24 months (range 12-36 months). Although the prevalence of major brain lesions was low, these infants have a higher risk of later neurodevelopmental disability, despite an early asymptomatic period. Universal neonatal brain ultrasound screening may help early diagnosis of rare major lesions, some of which have prognostic implications.

Agenesis of Corpus Callosum↗

PubMed2004

Experimental investigations of one liquid-crystal compound exhibiting the no-layer-shrinkage effect near the Sm-A-Sm- C(*) transition.

Three experimental probes have been employed to investigate the nature of the smectic- A -smectic- C ( Sm-A-Sm- C(*) ) phase transition of one liquid-crystal compound showing almost no layer-shrinkage effect through the transition. Results from both x-ray diffraction and optical studies indicate that the compound exhibits a crossover behavior of different molecular packing arrangements within the bulk Sm-A phase window. The calorimetry results show a significant critical anomaly near the Sm-A-Sm- C(*) transition, although it was found to be weakly first order.

Journal Article↗

PubMed2004

Infradiaphragmatic pulmonary sequestration combined with cystic adenomatoid malformation: unusual postnatal computed tomographic features.

We present a surgically proven case of infradiaphragmatic pulmonary sequestration combined with cystic adenomatoid malformation. Prenatal magnetic resonance imaging revealed a well-defined hyperintense mass with a hypointense septum in the left infradiaphragmatic region. Postdelivery computed tomography (CT) and 3-month follow-up CT showed replacement of intralesional cystic areas by solid content. Such unusual postnatal CT changes, to our knowledge, have not been previously documented.

Adult↗

PubMed2004

Symptomatic giant Müllerian duct cyst in an infant: radiographic and CT findings.

We report an unusual case of Müllerian duct cyst in an 8-month-old infant who presented with frequent vomiting and recurrent urinary tract infections. Computed tomography showed a midline giant cyst in the pelvic floor. Delayed enhanced computed tomography demonstrated contrast filling of the cyst, indicating a communication with the urotract. Subsequent cystourethrogram and surgery confirmed a giant Müllerian duct cyst.

Abdomen↗

PubMed2004

Mapping OI-4, a gene conferring resistance to Oidium neolycopersici and originating from Lycopersicon peruvianum LA2172, requires multi-allelic, single-locus markers.

Lycopersicon peruvianum LA2172 is completely resistant to Oidium neolycopersici, the causal agent of tomato powdery mildew. Despite the large genetic distance between the cultivated tomato and L. peruvianum, fertile F1 hybrids of L. esculentum cv. Money maker x L.peruvianum LA2172 were produced, and a pseudo-F2 population was generated by mating F, half-sibs. The disease tests on the pseudo-F2 population and two BC,families showed that the resistance in LA2172 is governed by one dominant gene, designated as 01-4. In the pseudo-F2 population, distorted segregation was observed, and multi-allelic, single-locus markers were used to display different marker-allele configurations per locus. Para-meters for both distortion and linkage between genetic loci were determined by maximum likelihood estimation, and the necessity of using multi-allelic, single-locus markers was illustrated. Finally, a genetic linkage map of chromosome 6 around the 01-4 locus was constructed by using the pseudo-F2 population.

Ascomycota↗

PubMed2004

Hypercalcaemia and haemophagocytic syndrome: rare concurrent presentations of disseminated tuberculosis in a dialysis patient.

Tuberculosis remains an important cause of infection in chronic haemodialysis patients. Frequent extrapulmonary involvement, non-specific presentation and limited diagnostic tools usually make early diagnosis difficult. Herein, we report on an 83-year-old female patient who had been on regular heamodialysis therapy for 15 years, who presented with asymptomatic hypercalcaemia and pancytopenia. Haemophagocytic syndrome was documented during the admission period. Mycobacterium tuberculosis was cultured from bone marrow 1 month after her demise. This case report highlights the non-specific manifestations of extrapulmonary tuberculosis in dialysis patients and the limited value of conventional diagnostic methods. We would like to recommend aggressive intervention and early tissue aspiration from possible infectious sites when tuberculosis cannot be completely ruled out. Disseminated tuberculosis should be considered as an indication of hypercalcaemia where haemophagocytic syndrome occurs simultaneously.

Aged↗

PubMed2004

Comparison of the severity of illness scoring systems for critically ill cirrhotic patients with renal failure.

BACKGROUND: Mortality rates of cirrhotic patients with renal failure admitted to the medical intensive care unit (ICU) are high. End-stage liver disease is frequently complicated by disturbances of renal function. This investigation is aimed to compare the predicting ability of acute physiology, age, chronic health evaluation II and III (APACHE II and III), sequential organ failure assessment (SOFA), and Child-Pugh scoring systems, obtained on the first day of ICU admission, for hospital mortality in critically ill cirrhotic patients with renal failure. METHODS: Sixty-seven patients with liver cirrhosis and renal failure were admitted to ICU from April 2001-March 2002. Information considered necessary for computing the Child-Pugh, SOFA, APACHE II and APACHE III score on the first day of ICU admission was prospectively collected. RESULTS: The overall hospital mortality rate was 86.6%. Liver disease was most commonly attributed to hepatitis B viral infection. The development of renal failure was associated with a history of gastrointestinal bleeding. Goodness-of-fit was good for SOFA, APACHE II and APACHE III scores. The APACHE III and SOFA models reported good areas under receiver operating characteristic curve (0.878 +/- 0.050 and 0.868 +/- 0.051, respectively). CONCLUSION: Renal failure is common in critically ill patients with cirrhosis. The prognosis for cirrhotic patients with renal failure is poor. APACHE III and SOFA showed excellent discrimination power in this group of patients. They are superior to APACHE II and Child-Pugh scores in this homogenous group of patients.

APACHE↗

PubMed2004

New approaches to surgery of lentigo maligna.

Lentigo maligna (LM) is a pigmented lesion that occurs most commonly on the sun-exposed skin of the head and neck of an older patient. LM can be difficult to completely remove due to its occasional extensive subclinical extension. Surgical treatments, including standard excision and margin-controlled excision (Mohs micrographic surgery or rush permanent sections), are reviewed. Immunostains that can increase sensitivity and specificity of margin-controlled excision are discussed, and other nonscalpel treatments including destruction, topical imiquimod, radiation therapy and cryotherapy are briefly discussed. The gold standard treatment for LM is margin-controlled excision.

Aged↗

PubMed2003

Unusual behavior of the surface-induced tilted layers in free-standing films of a non-layer-shrinkage liquid crystal compound.

Null-transmission ellipsometry has been conducted to study the molecular arrangements in free-standing films of one chiral compound above the bulk smectic-A-smectic-C* transition temperature. Upon cooling under a proper electric field, a nonplanar-anticlinic-synclinic or a nonplanar-synclinic transition has been observed. The nonplanar structure continuously evolves into the anticlinic or synclinic structures. Increasing electric field can induce a rare transition from a synclinic to an anticlinic structure.

Journal Article↗

PubMed2003

Optical studies on free-standing films of an achiral smectic liquid crystal.

Employing null transmission ellipsometry and depolarized reflected light microscopy, we have studied two smectic phases, Sm-C1 and Sm-C2, of one achiral mesogen. Our results show that Sm-C1 and Sm-C2 are the synclinic Sm-C and anticlinic Sm-C(A) phases, respectively. We find no evidence to support recent claims that the Sm-C1 is chiral and ferroelectric [R. Stannarius et al., Phys. Rev. Lett. 90, 025502 (2003)].

Journal Article↗

PubMed2003

Critical behavior of thermal parameters at the smectic-A-hexatic-B and smectic-A-smectic-C phase transitions in liquid crystals.

High temperature resolution measurements of thermal conductivity, thermal diffusivity, and specific heat, with simultaneous polarized light visual inspection of the sample, have been performed at two different liquid crystal phase transitions: the SmA-SmC (Smectic-A-Smectic-C) and the SmA-HexB (Smectic-A-hexatic-B) in racemic A7 [4-(3-methyl-2-chlorobutanoyloxy)-4(')-heptyloxybiphenyl] and 65OBC (n-hexyl-4(')-n-pentyloxybiphenyl-4-carboxylate) compounds, respectively. In the past, anomalies in the thermal conductivity at the transitions have been reported. Our results indicate a nonsingular behavior of the thermal conductivity at both transitions, similarly to what has been previously reported for the smectic-A-nematic phase transition. It is also shown how, in several cases, the nature of the transition can be affected by the sample thermal history due to the presence of strain annealing phenomena.

Journal Article↗

PubMed2003

Bacteria ascend to liver from the bilioenteric conduit after choledochojejunostomy in the cholestatic rat.

The high incidence of postoperative cholangitis in children with clinical restoration of bile flow after Roux-Y choledochojejunostomy (RYCJ) assumed the concept of a direct ascending cholangitis caused by pathogens in the intestine, into the intrahepatic bile duct via the porta hepatis. It is also well known that jaundiced animals (patients) are more susceptible to infections of the bile ducts following the procedure of bilioenteric anastomosis. An animal experiment was conducted to compare quantitative bacterial cultures of the choledochojejunostomy area and the liver 24 hours after Escherichia coli (ATCC 25922) or sterile normal saline was injected into the bilioenteric conduit (BEC), following RYCJ in rats with or without the proceeding bile duct ligation. A significant increase of E. coli of the same strain (ATCC 25922), that we injected into the BEC, was proved with pulse-field gel electrophoresis (PFGE) and shown in the liver of the jaundiced rats receiving E. coli (ATCC 25922), compared to that in the nonjaundiced rats with normal saline treatment. It is concluded that bacteria often ascend early to the liver from the BEC following RYCJ. This ascending cholangitis model might be produced for further studies.

Animals↗

PubMed2003

Optical characterization of a nanoscale incommensurate pitch in a new liquid-crystal phase.

As a remarkable orientationally ordered soft-condensed matter system, the smectic-C*(alpha) phase exhibits an incommensurate nanoscale helical pitch of more than four smectic layers. Recent theoretical advances predict the existence of a new phase showing a helical pitch of less than four smectic layers (<16 nm). By applying a novel optical technique to the study of freestanding films with increments in thickness of one smectic layer, we have measured the size of this pitch using 633 nm HeNe laser light. Our results confirm the existence of the newly predicted phase in one unique compound.

Journal Article↗

PubMed2003

Double reentrance of surface arrangements in freestanding liquid crystal films.

The molecular arrangement of tilted surface layers on freestanding films above the bulk smectic-A-smectic-C(*) transition has been studied by null transmission ellipsometry. In the presence of an applied in-plane electric field, a synclinic-anticlinic-synclinic-anticlinic double reentrance has been observed. Furthermore, we have characterized a novel transition from the synclinic arrangement to a structure in which the interior layers tilt in the same orientation and the outermost surface layers tilt oppositely with the interior layers.

Journal Article↗

PubMed2003

In-line liquid-crystal microcell polarimeter for high-speed polarization analysis.

We report a type of high-speed microcell polarimeter that utilizes microelectrodes, liquid-crystal films, and ultrathin high-contrast polarizers, all integrated between the tips of two optical fibers. When combined with optimized nematic liquid-crystal materials, this compact (2.5 cm x 0.5 cm x 0.5 cm) device offers excellent optical properties and continuous, high-speed operation at > 2 kHz with moderately low operating voltages. It requires no bulk optical elements, and it shows excellent performance when implemented for the measurement of degree of polarization in 10-Gbit/s test systems. Polarimeters based on this design have promising potential applications in polarization analysis for high-speed optical communication systems.

Journal Article↗

PubMed2003

Triplet-to-singlet exciton formation in poly(p-phenylene-vinylene) light-emitting diodes.

The triplet to singlet exciton formation ratio in a MEH-PPV light-emitting diode is measured by comparing the triplet-induced absorptions with optical and electric excitations at the same singlet exciton density. The ratio is a strong universal decreasing function of the averaged electric field. Using 4 ns for singlet to triplet intersystem crossing time, the ratio is significantly larger than the spin-independent value 3 at intermediate field but is reduced to about 2 for higher field.

Journal Article↗

PubMed2003

The effect of humic acid on the uptake of mercury(II), cadmium(II), and zinc(II) by Chinook salmon (Oncorhynchus tshawytscha) eggs.

The Chinook salmon (Oncorhynchus tshawytscha) is endangered or threatened in several of its ranges. The uptake of metals by Chinook salmon eggs and how humic acid (HA) affects the uptake is a subject of interest. Humic acid (0, 0.001, 0.01, and 0.05g/l) reduces the uptake of the metal ions Hg(II), Cd(II), and Zn(II), (1.0 microM) by eggs. HA is more effective in reducing the uptake of Hg than that of Cd or Zn. At [HA] = 0.001 g/L Hg uptake is reduced by 44% compared to no HA, while Cd and Zn uptakes are slightly or not reduced. Once the metals are taken up by the eggs, Hg migrates more slowly from the chorion to the yolk than either Zn or Cd. In experiments in which the metal contents of the chorion and yolk were measured at up to 24 h and five days after uptake, the order of migration was Cd > Zn > Hg. This observation is important when discussing the effects of metals on biological processes in the yolk because when Hg is taken up by eggs, a smaller percentage reaches the yolk than does Cd and Zn.

Animals↗