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Biomedical subjects

C C Ekwempu

Publications and source records attributed to C C Ekwempu.

28 records · Page 2Linked to original sources

Infection theory of eclampsia reevaluated.

One hundred eclamptic patients and an equal number of carefully observed parturient controls were investigated clinically, radiologically, hematologically and bacteriologically for evidence of infection on admission. At that time, 77% of the eclamptics, but none of the other group, were febrile (temperature greater than 38 C). Sepsis was evidently greater among the eclamptics than the controls. Significantly more eclamptic patients with fever had infections as well, compared to those who were nonfebrile. The association of fever and infection with eclampsia was so striking that the author speculates on the possibility of a cause-and-effect relationship.

Eclampsia↗

Postoperative morbidity of eclamptic patients delivered by cesarean section.

Postoperative morbidity was investigated in 32 eclamptic patients and 12 normal well-matched controls who had been delivered by cesarean section. The incidence of wound and chest infection, genital sepsis and puerperal psychosis was higher among the eclamptics than the controls. The former also harbored more pathogens in the throat, rectum, abdominal wound and cervix than the controls. It is concluded that eclamptic patients are more prone to sepsis after surgery and should be nursed with special care.

Bacterial Infections↗

Endometriosis among the Hausa/Fulani population of Nigeria.

In three and half years at the Ahmadu Bello University Hospital, Zaria, Nigeria, endometriosis was found in 27 Nigerians (all negroid) and one Caucasian. Age and parity distribution were similar to what has been found in patients elsewhere. In other respects, there were striking differences. The frequency (8.2 percent) is one of the highest reported in the negro. Two fifths were menopausal, majority had associated pelvic inflammatory disease, and nearly all were in women of the lowest socio-economic status. The lesions were rare in the pouch of Douglas and were totally absent from the rectovaginal septum and in the extra peritoneal space.

Adult↗

Continuation of abdominal pregnancy complicated by preeclampsia three weeks after birth of an intrauterine twin.

A case of heterotopic pregnancy in a 22-year-old multigravida is presented. The extrauterine baby was delivered alive three weeks after the intrauterine pregnancy had ended at term in spite of an associated preeclampsia. The inhibition of lactation resulting from the continuation of the extrauterine pregnancy resulted in marasmus for the first baby. The implications and especially the etiology of preeclampsia occurring in extrauterine pregnancy are discussed.

Adult↗

Familial polycystic kidney disease in Nigeria: a report of two cases.

A case of familial polycystic kidney disease is reported. Although isolated cases of adult polycystic kidney disease have been reported in our environment, no case to our knowledge has been reported with a familial link. Polycystic kidney disease is said to be rare in Africans. Although it commonly terminates in chronic renal failure, it hardly features in the aetiopathogenesis of end stage renal disease requiring some form of renal replacement therapy in African series. This, some workers believe may be due to misdiagnosis and under reporting. This report is to show that it may not be as rare as suspected, and that the familial link shown in the advanced countries is also applicable here. Case 1 was diagnosed in the course of evaluation of her clinical disease. Case 2, an aunt of Case 1, was diagnosed following investigation of a casual complaint of a painless abdominal mass in the wake of her senior brother's death from haemorrhagic stroke.

Adult↗

A simple mass-closure technique compared with layered technique in the closure of high-risk abdominal wounds.

A retrospective comparison of the outcome of patients with ruptured gravid uterus following obstructed labour who had abdominal closure by a simple mass-closure technique (using non-absorbable Nylon suture) with their counterparts who had the more popularly used layered technique. The clinical features on admission, operation details and wound complications were compared. Thirty-one patients who had mass-closure were compared with 103 that had the layered technique. Nineteen percent of the former had wound infections or partial dehiscences while none had complete dehiscence or hernias. On the other hand these respective complications occurred in 32%, 9.7% and 1.9% of the layered group. This mass-closure technique has the advantages of low-cost, speed and safety. We advocate that it be used on all high-risk abdominal wounds.

Adult↗