Biomedical subjects
Publications and source records attributed to C Boyer.
A leg pain is not always of venous origin. From thirteen clinical cases, various diagnoses are individualized: stress fractures, plantar static disorders, metatarsalgias, anterior and posterior muscular compartment syndromes.
The authors give an account of their observations of a female patient who was treated for a sprained ankle by an injection of a crystalline suspension of triamcinolone. This therapeutic procedure caused cutaneous and subcutaneous atrophy of the external malleolar region and a strip of atrophy right along the lymph course of the leg. This observation led to bibliographical research and a review of the histological and clinical phenomena characterizing this type of accident. They note that the medico-legal position of the practitioner may be in question.
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Antiidiotypic antibodies directed against the M-173 (IgG2a) mouse myeloma protein have been raised in syngeneic and allogeneic conditions. The antiidiotypic repertoires of several strains of mice have been compared by isoelectrofocusing, and a major idiotype has been identified by several antisera raised in allogeneic conditions in strains of mice which did not express the Igh-Ca allotype of the BALB background. Since this idiotype could be reformed in hybrid molecules containing the M-173 heavy chains and light chains which contained the J kappa 2 region, we propose that this determinant is dependent upon the J kappa 2, DH and JH regions, in addition, most probably, to a specific contribution of residues 45 and 54 of the heavy chains.
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