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Biomedical subjects

C Bouchet

Publications and source records attributed to C Bouchet.

At least 55 records · Page 3Linked to original sources
PubMed1983

[Acute thrombosis of the aortic bifurcation caused by heparin allergy. Apropos of 5 cases].

Five patients with humoral intolerance to heparin developed acute thromboses, with a fatal outcome in two cases from failure to establish the diagnosis, marked sequelae in one case, and recovery without complications in the other two. Accidents of this type may occur in 0.6 p. cent of patients on heparin therapy and are almost always fatal if administration is not discontinued. They result from a severe immunoallergic. Thrombocytopenia which may lead to the formation of arterial clots. Arterial thrombosis during heparin therapy is suggestive of the diagnosis and tests for diminished platelet counts are necessary. Apart from surgery, treatment involves the immediate cessation of heparin therapy.

Acute Disease↗
PubMed1983

[Axillary-subclavian injuries. Apropos of 11 cases. Procedural problems].

Tactical problems raised by treatment of injuries involving the axillary-subclavicular region were studied by analysis of 11 cases treated in a Grenoble hospital since 1975. The majority of patients had multiple injuries, and it was possible to perform pre-operative angiography in all cases. Lesions involving the mobile post-vertebral segment of the subclavian artery were treated by pre-sternocleidomastoid cervicotomy through a deltopectoral approach enlarged in L. Functional prognosis was related to the frequency and severity of associated neurological lesions.

Accidents, Occupational↗
PubMed1981

[Intramural hematomas of the small bowel (duodenum excluded) during long-term anticoagulant treatment. Report on 6 cases of which 2 required operation (author's transl)].

Hematomas developed in the small bowel of 6 patients receiving long-term anticoagulant therapy with antivitamins K. As the report by Chapuis and Mercier during the 81st French Congress of Surgery has fully covered this subject, the authors present their cases to illustrate their clinical features, while emphasizing certain particular characteristics: 1 - Associated hemorrhagic lesions were frequently observed. 2 - Early diagnostic follow-through barium meal examinations of the small intestine could be conducted without any particular problem. 3 - Laparotomy was necessary in two patients because of shock or local signs on examination. 4 - Small bowel lesions can vary in severity, sometimes in the same patient (case no 1). Some hematomas heal spontaneously after discontinuation of anticoagulant treatment, while others can, theoretically, develop necrotic reactions. Small bowel resection was necessary in two patients. 5 - A frequent occurrence was the association of lesions in the right colic and ileal regions. 6 - Finally, anticoagulant treatment can often be reduced, discontinued, or replaced by other therapy.

Adult↗
PubMed1980

[Septicemia following infection of an endocardial electrode lead (author's transl)].

The authors report one case of septicemia following the infection of a remaining endocardial electrode lead. From this observation and the literature's data, they are thinking that it is essential to remove the entire pacemaker system (electrode lead and generator) to cure this complication. They remind the different technics used to remove the endocardial leads.

Adult↗
PubMed1980

[Mesenteric clamp syndrome complicating pancreatic trauma (author's transl)].

Duodenal obstruction by the mesenteric artery has mostly been reported in profoundly denutrated patients. We here report one case after left spleno-pancreatectomy following pancreatic isthmus rhexis concerning a seventeen years old injured young boy, who was kept in supination position because of a backbone fracture. Vertebral osteo-synthesis allowed a quickly efficient postural treatment.

Adolescent↗
PubMedDate not supplied

Limited prognostic value of c-erbB-2 compared to uPA and PAI-1 in primary breast carcinoma.

In a retrospective study of 488 women with primary breast cancer, after a median follow-up of 10 years, we sought interactions between disease-free survival (DFS) and overall survival (OS) and tumor antigen levels of two components of the plasminogen system, urokinase-type plasminogen activator (uPA) and its inhibitor PAI-1, and the transmembrane growth factor receptor c-erbB-2. We used ELISAs (American Diagnostica, Greenwich, CT, USA) to quantify uPA and PAI-1 antigen levels in cytosols, and a double monoclonal antibody-based assay (EIA) (Ciba Corning Diagnostics, Alameda, CA, USA) to quantify c-erbB-2 in membrane extracts of the same tissues. Weak positive correlations were found between uPA and c-erbB-2 (r(s) = 0.146; p = 0.001) and between PAI-1 and c-erbB-2 (r(s) = 0.154; p < 0.001). In the overall population, using univariate analyses, c-erbB-2 overexpression and high uPA and PAI-1 antigen levels (> 300 IU/mg, > 1.40 ng/mg and > 5.53 ng/mg, respectively) were significantly associated with shorter DFS (p = 0.003, p < 0.001 and p < 0.001, respectively) and OS (p < 0.001 in all cases). Using multivariate analyses, PAI-1, node status and tumor size were independent predictors of DFS and c-erbB-2 was retained in the model only for OS. In the node-negative subgroup, PAI-1 was the strongest significant survival predictor both for OS (p = 0.003; HR 2.52) and DFS (p < 0.001; HR 2.39). This study shows that in primary breast cancer c-erbB-2 offers no additional prognostic information when uPA and/or PAI-1 are candidates in the multivariate analyses.

Adult↗
PubMedDate not supplied

[Syndrome of irregular maturation of the endometrium].

Following their study on biopsies in a group of tunisian women the authors insist on the unchanged histologic and clinic characters of the irregular ripening syndrome of the endometrium, as described in 1928. They suggest a mediation by the oncocyte for the use of oestrogens in glandular site.

Endometrium↗
PubMedDate not supplied

[Treatment of facial neuralgias: retrogasserian thermocoagulation under iterative discontinuous narcosis with propanidid].

Coagulation of the Gasserian ganglian is currently recommended in the treatment of trigeminal neuralgia due to the slight risks that it presents. It is accompanied by brief but intense periods of pain which necessitate the need of an Anaesthetist. As well as we have been able to verify in the course of sixty-two of these procedures, a discontinuous narcosis obtained by reiterated injections of propanidid presents a satisfying solution. It permits the neurological examinations, which need absolute cooperation of the patient, before each new coagulation to be accomplished in good conditions.

Aged↗