Search PubMed⌕ Search

Biomedical subjects

C Bode

Publications and source records attributed to C Bode.

At least 235 records · Page 13Linked to original sources
PubMed1976

[Effect of some choleretics on the hepatic flow and its composition in man].

Four choleretics, selected at random from the German list of medical preparations, were tested with regards to their influence on hepatic bile production and bile composition. The investigations were performed on patients with a T-drainage in the ductus choledochus after bile duct revision. Bile was collected after fasting (90 min) and after administration of the drugs to be tested (3 hours). The choleretics were administered orally in a dosage two to five times more than the recommended one. Besides the bile volume bile acids, cholesterol, bilirubin, bicarbonate, potassium, sodium and calcium were determined. None of the parameters could be definitely influenced by these drugs. On the other hand a pronounced increase in the bile flow as well as the expected change in the other parameters could be observed after standardized secretion-stimulation which had been additionally carried out in half of the patients (dehydrocholic acid, i.v., taurocholic acid intraduodenally, secretin i.v., meals).

Adult↗
PubMed1972

Stimulatory effect of pancreozymin-cholecystokinin on calcium secretion in pancreatic juice of dogs.

In four dogs with a permanent duodenal Thomas fistula the secretion of calcium, sodium, potassium, protein, and two pancreatic enzymes in pancreatic juice was studied. Infusion of secretin led to a decrease in concentration of calcium and of protein with increasing rates of fluid production. Pancreozymin-cholecystokinin was given in single injections superimposed on the secretin-stimulated flow of juice. This hormone stimulated the secretion of both calcium and enzyme protein in a parallel and closely correlated fashion. The secretion of this protein-bound calcium fraction I is assumed to occur in the acinar cell. A calcium fraction II, which was independent of protein secretion and pancreozymin stimulation, was demonstrated in concentrations of about 0.4 to 0.6 m-equiv/l. This fraction is thought to originate in the interstitial fluid. The secretion of two calcium-containing fluids is in accordance with the two-component theory of secretion proposed by Hollander and Birnbaum (1952).

Animals↗