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Biomedical subjects

C Blundo

Publications and source records attributed to C Blundo.

8 recordsLinked to original sources
PubMed1990

Perception of ambiguous figures after focal brain lesions.

Forty patients with unilateral frontal or posterior brain damage and 20 normal control subjects were tested on an ambiguous figures task (AFT). For each figure they were asked to recognize both ambiguous images. Subjects failing to recognize the second aspect of an ambiguous figure were prompted with the name of the image not yet perceived. The Wisconsin Card Sorting Test (WCST) was also administered to all subjects. Frontal patients exhibited greater difficulty in shifting from one aspect of an ambiguous figure to the other than did patients with more posterior lesions and control subjects. In addition, frontal-posterior and control differences were highly significant for number of prompts given. For the frontal patients, significant correlations were found between the number of prompts on the AFT and the number of perseverative errors on the WCST. Poor performance on the AFT can be considered as a "frontal lobe sign" of perceptual persevation.

Adult↗
PubMed1989

Avoidance conditioning in amnesia: a single case experimental study.

We present a single case study of avoidance conditioning in a seriously amnesic patient with bilateral ischemic lesions of the brain. A four-path maze was used for conditioning. The procedure consisted in an aversive stimulus that the patient received every time he traced one of the four maze-paths connected to an electric shock generator with a stylus. Using a single case experimental design A-B-A, we found that the patient learned to avoid the path connected to the electric shock, although he never showed awareness of this. Our study confirms once again that conditioning is one of the residual learning capabilities in amnesic patients. Different neural systems are probably involved in conditioning processes.

Amnesia↗
PubMedDate not supplied

Surgical treatment of the distal anterior cerebral artery aneurysms.

A series of eleven patients with aneurysms of distal anterior cerebral artery, microsurgically operated and submitted to accurate neuropsychological testing, is reviewed. Of these, ten patients had an aneurysm at the bifurcation of distal ACA into pericallosal and callosomarginal branches and only one patient had an aneurysm at the beginning of the fronto-polar artery. All our patients were operated by an interhemispheric approach, that was associated in 3 cases to a pterional approach in order to clip a second aneurysm in other location. The postoperative grade was satisfactory in any of the eleven patients. The aneurysms of distal ACA may be surgically obliterated through a variety of approaches but the exposure via the interhemispheric fissure is used by many neurosurgeons. In our experience the interhemispheric approach allows the exposure of feeding artery and the control of proximal vessel without morbidity. Some authors have modified the interhemispheric approach to improve, in their opinion, surgical exposure, introducing partial resection of anterior portion of corpus callosum, used, by them, especially for the aneurysms just beneath the genu of corpus callosum. Although resection of the anterior 2.5 cm of the corpus callosum can be performed without causing any neurological deficit, as reported by the same authors, the use of this technique might not be necessary. The present paper deals with current surgical techniques and their modification for the treatment of distal anterior cerebral artery (ACA) aneurysms.

Adult↗