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Biomedical subjects

C Bianchi

Publications and source records attributed to C Bianchi.

At least 559 records · Page 31Linked to original sources
PubMedDate not supplied

[Hyperthyroidism in childhood].

Pathogenesis of Graves' disease, the most frequent cause of infantile hyperthyroidism, is not definitely clarified. The role of thyroid stimulating immunoglobulins as the cause of hyperthyroidism, goiter and exophthalmos in Graves' disease is analytically considered. Genetic factors are also discussed. The Authors report some personal clinical observations emphasizing the polymorphic clinical course of the infantile Graves' disease. The diagnostic procedures and the therapeutical management are successively analyzed. Pathogenesis and clinical picture of neonatal thyrotoxicosis and Plummer's disease, two not frequent conditions, are finally examined.

Adenoma↗
PubMedDate not supplied

[Association breast cancer-meningioma. Report of two cases (author's transl)].

The theoretic and clinical interest of the association between breast cancer and meningioma is underlined. In both reported cases two women, which respectively two and three years ago, had undergone mastectomy operation due to breast cancer, showed symptoms and signs of cranial tumor. The operation revealed the diagnosis of meningioma in both instances permitting effective treatment of the lesion.

Brain Neoplasms↗
PubMedDate not supplied

[Bilateral sexual cord tumors in male pseudohermaphroditism].

Authors report a case of male pseudohermaphroditism reared as a female since birth. At abdominal exploration gonads showed the histologic pattern of immature testes, but were almost completely replaced by sex-cord mesenchymal tumors. It is remarked the opportunity of removing dysgenetic gonads earlier than usually suggested.

Child↗
PubMedDate not supplied

[Follow-up and prognosis of congenital hypothyroidism].

Neonatal screening of congenital hypothyroidism has been recently extended to the most of North America, Australia, Europe, and to several Italian areas. Before screening programs, several Authors reported neurological defects and behavioral disturbances also in patients whose treatment has been precocious, thus stressing the importance of an antenatal thyroidal defect. We have therefore setted up a follow-up program to evaluate the prevalence and to treat such disturbances in hypothyroid children. In this report we describe the program, present the most significant preliminary data and discuss the prognosis of hypothyroid patients detected by screening programs.

Adolescent↗
PubMedDate not supplied

[Hormonal therapy of congenital hypothyroidism in childhood].

L-tiroxine (L-T4) substitutive therapy has been evaluated in a group of 15 hypothyroid children (6 males and 9 females), one to six years old. We have found a wide dosage range, being not possible to find any significant difference between ranges leading to normal and ranges leading to pathological findings, thus making impossible to suggest a reasonably safe dosage pro kg. of body weight. Increasing L-T4 dosage we have got a significant increase of FT4 levels, a significant decrease of TSH levels, but no variations of FT3 values, indicating an individual capability in regulating FT3 disposal. FT3 and TSH are the most valuable indexes of therapy adequacy, since their normality reflects an euthyroid status; we should achieve an individually adequate dose of L-T4, based on clinical judgment and hormonal findings.

Congenital Hypothyroidism↗