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Biomedical subjects

C Bernard

Publications and source records attributed to C Bernard.

At least 433 records · Page 24Linked to original sources
PubMedDate not supplied

[Esophageal communication with a totally sequestrated hypoplastic right lung].

Pulmonary sequestrations involving communication with the digestive tractus are known as bronchopulmonary foregut malformations. The authors add a peculiar case report: there was an hypoplastic right lung with a total sequestration from the bronchial tree and communicating with esophagus. This was fed from the pulmonary vasculature without collateral artery formation. The pulmonary vein was normal. Association with a facial dysmorphia and an occipital meningocele is also of interest. The radiological diagnosis is based on the pulmonary X-Ray and the oesophagogram.

Abnormalities, Multiple↗
PubMedDate not supplied

[Bone lipoma in children. Apropos of a case].

Intra-osseous lipoma is rare in children. We report a case of the distal ulna which appeared in the beginning as an osteochondroma and later on as a chondroma. Resection of the distal end of the ulna was performed and the diagnosis of lipoma could be established. Six similar cases in the literature have been collected in children.

Bone Neoplasms↗
PubMedDate not supplied

[Results of home assisted ventilation of non-paralytic and tracheostomized chronic respiratory insufficient patients (author's transl)].

The following results have been obtained from a study of 118 tracheostomized patients ventilated at home: --Survival on the whole is generally prolonged. --The prognosis of tracheostomized subjects with restrictive syndrome is totally modified in length and quality when the patients are ventilated. --In the case of obstructive syndrome, the length and quality of survival are probably increased. However, it seems that assisted ventilation at home leads only to the disappearance of asphyxiating paroxysms and right cardiac failure. It does not seem to prevent the unrelenting evolution of the disease.

Adult↗
PubMedDate not supplied

[Role of computed tomography in the diagnosis and surveillance of hepatic alveolar echinococcosis].

Based on findings in 28 cases of hepatic alveolar echinococcosis, the most frequently encountered signs constituting a true "scannographic profile" are described. These include global hypodensity with poor or absent intensification of image after iodized contrast, very high frequency of intralesional calcifications often combined with necrotic plaques, peripheral retraction. Employed after standard radiologic imaging and ultrasonography, the scanner should be used to provide positive confirmation of the diagnosis of the parasitosis, and as a reference element in evaluation of intra- and peri-hepatic extension, both during the moment of choice of initial therapy and during follow-up reviews.

Adult↗
PubMedDate not supplied

Pulmonary function tests and airway responsiveness to methacholine in chronic bronchiectasis of the adult.

Fifty adults with chronic bronchiectasis (mean duration since diagnosis: 25 +/- 16.4 years), excluding those cases secondary to tuberculosis or hypogammaglobulinemia, were investigated by a questionnaire, a chest radiograph and lung function tests. Of these, 29 with an FEV1 greater than 1.5 1 underwent methacholine inhalation tests. Fourty-three subjects and three subjects respectively showed an obstructive or a mixed obstructive and restrictive defect, only four having normal lung function tests. Sixty-nine percent of subjects tested had a provocative concentration of methacholine causing a 20% fall in FEV1 (PC20) less than 16 mg X ml-1. Subjects with daily sputum production had lower values of FEV1 and FEV1/forced vital capacity (FVC) compared to subjects with less than daily sputum. Subjects with clinical features of bronchial hyperexcitability had significantly lower baseline FEV1, vital capacity, and maximal mid-expiratory flow rate (FEF25-75). Subjects with lower PC20 values had significantly lower baseline FEV1, FEV1/FVC and FEF25-75. Finally, subjects with the greatest extent of radiological abnormalities had lower baseline FEV1, FEV1/FVC and diffusing capacity, and a higher residual volume. We conclude that chronic bronchiectasis is associated with significant changes in lung function tests and increased responsiveness to methacholine in the majority of affected individuals.

Adult↗
PubMedDate not supplied

[Hemimelic epiphyseal dysplasia. Apropos of a case].

Dysplasia epiphysealis hemimelica (tarsomegaly, Trevor's disease) is a rare osteochondrodystrophy producing cartilaginous epiphysial hypertrophy of hemimelic type involving mainly the lower limb. Lesions are generally medialy located (medial condyle of the femur, medial malleolus, talus, tarsal scaphoid and first metatarsal bone) and clinical signs are not specific; therefore radiological diagnosis is very important. The disease gives rise to a massive ossification of the hypertrophic cartilaginous areas and fast degenerative changes (arthrosis) of the involved joints. Surgery is often unsuccessful.

Child, Preschool↗
PubMedDate not supplied

Cytokines, immuno-inflammatory response and atherosclerosis.

The importance of the immuno-inflammatory processes involved in the pathogenesis of atherosclerosis has been reconsidered since the various cellular components of the atherosclerotic plaque were more precisely characterized. Macrophages and T lymphocytes, as well as endothelial and smooth muscle cells are involved in the formation of the fibrolipidic lesion. This is suggestive of a delayed-type hypersensitivity reaction, with oxidized low-density lipoproteins (LDL) as possible antigenic stimulus. Cytokines, which are mediators of the immuno-inflammatory response, are locally expressed in the atherosclerotic plaque; they coordinate cell interactions and modulate the functions of vascular cells.

Antibody Formation↗