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Biomedical subjects

C Barron

Publications and source records attributed to C Barron.

22 records · Page 2Linked to original sources

Genital ulceration in males at Ga-Rankuwa Hospital, Pretoria.

One hundred previously untreated Black male patients presenting with genital ulceration were seen as outpatients at Ga-Rankuwa Hospital, Pretoria. Syphilis was the commonest cause of ulceration, being present alone in 33% of patients. Chancroid occurred almost as frequently, being found alone in 28% of cases. A double infection with both syphilis and chancroid occurred in a further 16%. Herpes genitalis was found alone in 4% and together with chancroid in 1%. One patient was found to have granuloma inguinale and another had lymphogranuloma venereum. In 16% of the patients no cause for the ulcerations could be found.

Adolescent↗

[Adrenal function in topic corticotherapy].

It has been shown that corticosteroids for dermatological use produce an inhibition of the adrenal function, and it is considered that in our milieu these products are used without any precise indication. In this study, 29 ambulatory children from 3 to 15 years of age were selected, who were suffering from dermatoses with different degrees of extension, on whom urinary 17-ketosteroids, 17-ketogenicsteroids and serum cortisol were measured before and after non-occlusive treatment of two weeks, using 0.01 percent fluorocorticoids and controls after 24 hours and 8 days. A significant drop of the 17-keratogenicsteroids was found in patients studied at the end of the treatment, with immediate recovery. Additionally it was observed, in patients who had over 30 percent of skin area involved, that there was a decrease in serum cortisol, which persisted even 24 hours after discontinuing treatment, with normal levels in a measurement taken eight days later. It is therefore concluded that glucocorticoids applied topically are capable of inhibiting adrenal function.

17-Ketosteroids↗