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Biomedical subjects

C Bahary

Publications and source records attributed to C Bahary.

30 records · Page 2Linked to original sources

Impact of placenta previa on intrauterine fetal growth.

The impact of placenta previa on intrauterine fetal growth was studied over a 10-year period, 1968-77. Fetal growth was assessed at the time of delivery by measurement of four parameters--birthweight, length, and head and chest circumferences. For 129 deliveries associated with placenta previa, these parameters were plotted against gestational age on Usher and McLean intrauterine growth curves. Fetal growth was significantly retarded as judged by all four parameters. When the results were analyzed according to the number of vaginal bleeding episodes, different patterns were found for the parameters studied. Retardation in chest circumference was unrelated to gestational age or number of bleeding episodes. Retardation in weight and chest circumference appeared at an early gestational age (25th week) and was more pronounced in the group with repeated episodes of bleeding. Retardation in head circumference and length appeared later (from the 32nd week of gestation) and was also more pronounced in the group with repeated vaginal bleeding. In women who had only one bleeding episode and in whom gestation continued to the 38th week or longer, birthweight, but none of the other three parameters, was consistent with the week of gestation. The results show that birthweight alone is insufficient to estimate intrauterine fetal growth retardation.

Female↗

Cytologic evaluation of hormonal dynamic in the postmenopause.

There is increasing evidence that the postmenopausal ovary retains some endocrine function and thus can contribute a certain extent to the persistence of the vaginal epithelium proliferation a long time after the cessation of menstruations. Vaginal cytology plays an important role in the assessment of the vaginal epithelium response to hormonal stimuli, though less accurate than the blood and the urine estimations. It was established that there was a good correlation between the vaginal cytology and the biochemical estimations [2]. The fact that vaginal cytology cannot distinguish the proliferative patterns induced by estrogens, progesterone and androgens is true. With this in mind we did a cytological study in postmenopausal women, using our classification for the cytological typing based on the depth of the epithelial atrophy. The findings are discussed with special reference to the ethnic origin, reproductive life and concurrent illnesses.

Aged↗

Transitory hypoadrenalism due to long-term treatment with antiovulatory compounds.

A considerable number of women receiving antiovulatory compounds or estrogens complain of weakness and fatigability, suggesting a state of clinical hypoadrenalism. For this reason, levels of plasma ACTH and plasma cortisol were determined in 25 women with such complaints both during treatment and at various intervals after cessation of this treatment. The results obtained showed that there was a significant inhibition of ACTH secretion during long-term treatment with antiovulatory compounds or estrogens, and in half of the cases, there was a delay in normalization of the pituitary-adrenal axis following interruption of the drug, supporting a state of transitory hypoadrenalism.

Adrenal Insufficiency↗

Ectopic pregnancy, the new gynecological epidemic disease: review of the modern work-up and the nonsurgical treatment option.

Over the past few decades, the incidence of ectopic pregnancy has increased almost to the extent of an "epidemic disease." Early diagnosis of tubal pregnancy, with the aid of serum human chorionic gonadotropin, high-resolution ultrasound, and the more liberal use of laparoscopy, has dramatically reduced both maternal mortality and the need for radical surgery. Despite this, women with previous ectopic pregnancies still have reduced fertility potential. We report on some current aspects of the epidemiology, etiology, and work-up of ectopic pregnancy. In a review of 328 patients, gleaned from the literature, who were treated with various nonsurgical options, 283 (86%) were able to avoid surgery. The benefits, safety, and efficacy of the various treatment options are discussed, with appropriate recommendations for their use.

Female↗

Growth hormone--non multum sed multa (quality, not quantity).

In view of the recent availability of recombinant human growth hormone (GH) and reports of its ability to augment ovulation induction by exogenous gonadotropins, we have surveyed the reproductive physiological role of GH and the family of polypeptides that mediate its action. The clinical studies using GH to improve ovulation induction, although achieving a significant reduction in exogenous gonadotropin administration, show only minor benefits in terms of attainment of pregnancy. An explanation for this phenomenon is suggested, and we provide guidelines for whom GH should be recommended.

Animals↗