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Biomedical subjects

C Bagley

Publications and source records attributed to C Bagley.

68 records · Page 4Linked to original sources

Effect of psychiatric intervention in attempted suicide: a controlled study.

All patients presenting at the casualty department of King's College Hospital during the first six months of 1968 with deliberate self-poisoning or self-injury were followed up. Of 211 patients 204 (97%) were traced after a mean interval of 18 months (range one to two years). Despite official hospital policy, 22% had not been seen by a psychiatrist before discharge; these 44 untreated patients were compared with the remaining 160 who had received either brief (one or two interviews) or more prolonged psychiatric and social help.Subsequent suicidal attempts occurred significantly more often among untreated than among treated patients, prolonged treatment being associated with the best prognosis. The same trend was observed in respect of actual suicide, though the numbers were small and differences did not reach statistical significance. These findings held good when the untreated and treated groups were controlled for other variables which were found to be correlated with outcome. These results indicate that psychiatric intervention is associated with a significant reduction in subsequent suicidal behaviour.

Adjustment Disorders↗

Warthin's tumor: a functional immunologic study of the lymphoid cell component.

The origin and nature of the lymphoid cell component of Warthin's tumor are controversial. The present report describes the application of immunologic functional testing to the study of Warthin's tumor lymphocytes. Numbers of B and T cells are comparable to those of other lymph nodes. A vigorous stimulatory response to phytohemagglutinin reflects the predominance of functional T cells. These findings, in conjunction with morphologic observations, support the concept that the lymphoid component of Warthin's tumor is derived from a pre-existing lymph node.

Adenolymphoma↗

Survival hazards analysis in first recurrent breast cancer patients: seven-year follow-up.

The purpose of this study was to identify predictors of survival time in first recurrent breast cancer patients, including psychologic as well as biologic factors. Beginning in 1979, 36 women being treated at the National Institutes of Health for histologically proven recurrent disease were enrolled in this prospective study. At the time of data analysis, 24 had died from their malignancy. Through the use of a Cox proportional hazards model, four factors significantly entered the equation predicting survival time in the sample: Patients with a longer disease-free interval, who expressed more joy at baseline testing, who were predicted to live longer by their physicians, and who had fewer metastatic sites tended to live longer with recurrent disease than others in the sample (X2 = 22.9, p less than 0.0001). Findings from recent clinical and animal studies suggest that regulatory systems within the organism are linked and potentially influence one another. This study has demonstrated that factors at a number of levels--behavioral, as well as biologic--need to be considered in accounting for disease outcome variance.

Adaptation, Psychological↗