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Biomedical subjects

C B Payne

Publications and source records attributed to C B Payne.

At least 19 recordsLinked to original sources
PubMed1998

Hospital discharges for diabetic foot disease in New Zealand: 1980-1993.

The aim of this study was to determine the prevalence of hospital discharges for diabetic foot disease from 1980 to 1993 in New Zealand and identify regional variations. Data from the International Classification of Disease (ICD) discharge codes for diabetes and its complications from 1980 to 1993 were reviewed for diabetic foot disease. The total number of discharges/100,000 total population has increased from 13.56 in 1980 to 25.79 in 1993. The age and sex-standardised total bed/days per 1000 total population increased from 5.02 in 1980 to 5.85 in 1993. The total inpatient cost for the management of diabetic foot disease in New Zealand (population 3.3 million) for 1993 is estimated to be in the region of NZ$10-11 million (USD$7-7.7 million), indicating the need to put strategies in place to manage this problem. Strategies that reduce the individual and inpatient burden of this advanced stage complication of diabetes mellitus can be implemented easily for a relatively modest cost.

Adult↗
PubMed1998

The past, present, and future of podiatric biomechanics.

The author places the history and development of podiatric biomechanics, as well as current thinking about its underpinnings and future, in the context of a theoretical framework drawn from the philosophy and sociology of science. This analysis sets the stage for an exploration of the possible future directions in which podiatric biomechanics could develop.

Biomechanical Phenomena↗
PubMed1998

Biomechanics of the foot in diabetes mellitus. Some theoretical considerations.

Although diabetes mellitus is a biochemical disease, it has biomechanical consequences for the lower extremity. Numerous alterations occur in the function of the foot and lower extremity in people with diabetes. This article evaluates biomechanical alterations of the foot in the presence of neuropathy in patients with diabetes in the context of several theoretical concepts. Further study of these hypotheses will result in a better understanding of how diabetes causes elevated plantar pressures and the potential of strategies to prevent these changes so that the burden of diabetic foot disease can be reduced.

Biomechanical Phenomena↗
PubMed1995

Pulmonary hyalinizing granuloma: an unusual association with multiple sclerosis.

Pulmonary hyalinizing granuloma (PHG) is a rare entity included in the differential diagnosis of pulmonary nodules of unknown origin. The pathologic entity may represent a peculiar form of pulmonary immune reaction. We report the case of a 40-year-old white woman who had nodular lesions in both lung bases after a 10-year history of multiple sclerosis. An open lung biopsy was required to make the diagnosis. The association of pulmonary hyalinizing granuloma with multiple sclerosis could be coincidental, but since there is a possibility of immune reaction in the pathogenesis of both diseases, the association may be significant.

Adult↗
PubMed1991

Regional and systemic CD4 and CD8 subsets in bronchogenic carcinoma.

We studied lung and blood lymphocytes from 12 asymptomatic patients with peripheral bronchogenic carcinoma. Bronchoalveolar lavage was performed in the lung segment with tumor and a contralateral uninvolved lung segment and analyzed separately. After partial removal of macrophages by plastic adherence, cells were labeled with markers for CD4 and CD8 and analyzed by flow cytometric analysis. We found no significant difference in the percentages of mononuclear cells in either immune subset when comparing the lung containing tumor with the uninvolved lung. We did find, however, a depressed CD4/CD8 ratio in the peripheral blood. We conclude that a lung carcinoma does not change the local immunologic milieu of the lung parenchyma containing the carcinoma. It is not clear if the immunologic findings in the lungs and blood are due to the bronchogenic carcinoma, smoking, or the underlying chronic obstructive pulmonary disease.

Aged↗
PubMed1990

Mediastinal radiographic abnormality caused by anomalous venous drainage: how often is it seen in Afro-Americans?

An abnormal superior mediastinal density seen on a chest x-ray led to computerized tomography scan detection of an enlarged azygous vein produced by anomalous embryologic development of the inferior vena cava. This potentially clinically important abnormality is uncommon and statistics indicating its frequency are best available from the Japanese. In addition to alerting clinicians to this abnormality, a plea is made for review of autopsy series in Afro-Americans by pathologists in order to determine potential risks in a variety of surgical procedures.

Aged↗
PubMed1988

Neoplastic obstruction of the trachea complicating pseudobulbar palsy.

We have reported a case of pseudobulbar palsy with airflow obstruction initially attributed to chronic aspiration and chronic airflow obstruction caused by cigarette smoking. The finding of stridor led to a detailed evaluation of the obstruction. Flow-volume loops, fiberoptic bronchoscopy, CT scan of the upper thorax, and fine-needle biopsy of a lesion of the trachea were required to make the diagnosis of non-small-cell carcinoma involving the trachea.

Airway Obstruction↗
PubMed1986

Effects of transoral and transnasal fiberoptic bronchoscopy on oxygenation and cardiac rhythm.

The association of hypoxemia and cardiac arrhythmias with fiberoptic bronchoscopy (FOB) is known. The effects of various methods of inserting the bronchoscope on blood oxygen tensions, the true prevalence of arrhythmias, and the clinical significance of PaO2 and rhythm changes are poorly defined. Arterial blood gas values, oxygen saturation and cardiac arrhythmias detected by 24-hour Holter monitoring were compared in 20 male patients undergoing either transoral or transnasal FOB. No significant difference in oxygen saturation was found; however, PaO2 values fluctuated widely and unpredictably and were significantly higher in the eight patients in the transnasal FOB group. No life-threatening arrhythmias were induced during bronchoscopy; however, because of minor arrhythmias such as sinus tachycardia, the overall frequency of arrhythmias rose from 60% to 65%. The incidence of arrhythmias in this study was similar to that reported during pulmonary function testing.

Adult↗
PubMed1984

Nonpulmonary causes of dyspnea.

Dyspnea as a symptom is often related to pulmonary disorders. However, nonpulmonary disorders could be significantly responsible for causing dyspnea. Basic pathophysiology and clinical approach to nonpulmonary disorders causing dyspnea are discussed in this article.

Anemia↗
PubMed1983

Two-step tuberculin testing in a veterans domiciliary population.

Seven hundred ninety-six veterans were scheduled for tuberculin testing during a hospital/domiciliary employee health program in southern Ohio. The Mantoux test, using 5 TU of commercial purified protein derivative (PPD) was used. Nonsignificant reactors were retested at one week to detect and quantitate the "booster phenomenon," following Centers for Disease Control (CDC) recommendations. Cost data were recorded. The initial frequency of 39.3% reactions greater than 10 mm in 740 tested subjects increased to 46.7% on two-step testing. Fifty-five of 414 subjects exhibited the booster effect, a rate intermediate between that reported in Alabama and no boosting reported in Rochester, New York. Costs of two-step testing exceeded, by a small margin, estimated costs of isoniazid preventive therapy for apparent converters detected by two-step testing.

Adult↗
PubMed1978

Papillomas of the tracheobronchial tree with malignant degeneration.

Papillomas are rare tumors of the respiratory tract, which are usually considered benign. We studied a male patient with adult onset of squamous papillomatosis involving both the trachea and the bronchi, with malignant degeneration. When we obtained specimens bronchoscopically, only the bronchial lesions showed carcinomatous changes. Thoracotomy demonstrated carcinoma in the tracheal lesion as well. We conclude that transbronchoscopic biopsy may be inadequate in the evaluation of papillomatosis.

Bronchi↗