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Biomedical subjects

C B FAVOUR

Publications and source records attributed to C B FAVOUR.

53 records · Page 3Linked to original sources
PubMed1951

The lymphocytic origin of a plasma factor responsible for hypersensitivity in vitro of tuberculin type.

Methods are described for the evaluation in vitro of the effect of tuberculin on the leucocytes of peripheral blood. Washed leucocytes from a tuberculin sensitive host suspended in normal plasma are not lysed by tuberculin until after several hours of contact. Washed leucocytes from a tuberculin-sensitive host slowly release into normal plasma a factor which will cause the lysis of normal leucocytes exposed to tuberculin. Dialysis of normal plasma containing shed plasma factor causes the latter to precipitate with the euglobulins. Shed plasma factor can be recovered from normal plasma which has been incubated with lymphocytes from tuberculin-sensitive hosts. Suspensions of neutrophils do not yield shed plasma factor.

Humans↗
PubMed1951

The effect of adrenocorticotropic hormone on inflammation due to tuberculin hypersensitivity and turpentine and on circulating antibody levels.

The treatment with adrenocorticotropic hormone of guinea pigs sensitized with heat-killed tubercle bacilli caused suppression of their skin reactivity to tuberculin. Similar animals treated with saline did not show this change. Normal guinea pigs treated with adrenocorticotropic hormone showed suppression of inflammation, but not necrosis, produced by intracutaneous oil of turpentine. There was slight, but probably not significant, diminution of inflammation during saline administration. Tuberculin complement-fixing antibody titers were not altered by either adrenocorticotropic hormone or saline administration. Adrenocorticotropic hormone produced marked eosinopenia and lymphopenia in guinea pigs.

Adrenocorticotropic Hormone↗