Biomedical subjects
C B Adams
Publications and source records attributed to C B Adams.
Effects of intracranial dopamine perfusion: behavioural arousal and reversal of cerebral arterial spasm following surgery for clipping of ruptured cerebral aneurysms.
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Intracranial aneurysms: analysis of results of microneurosurgery.
Subarachnoid haemorrhage from intracranial aneurysms has a poor prognosis. Operative management of intracranial aneurysms was once considered ineffective. The first 100 cases treated by micorsurgery were analysed to see whether mortality and morbidity were reduced. Modern surgical techniques halved the total mortality but the morbidity was unaltered. Results can be improved by delaying surgery seven days and by treating any hypertension before surgery.
Acquired dyslexia: patterns of deficit and recovery.
These preliminary results are concerned with the quantitative description of recovery of function and the shape of the recovery curve. Four patients, in whom dylexia was the salient residual symptom of cerebral damage, are described. Individual differences in the pattern of dyslexic error and the time course of recovery are discussed; and recovery--as measured by longitudinal studies of performance in reading tasks--is analysed in terms of a model which takes into account rate of learning and the eventual asymptote. It is suggested that these or analogous techiques may be relevant both for the design of remedial programmes and for problems of prognosis.
Responses of isolated human basilar arteries to 5-hydroxytryptamine, noradrenaline, serum, platelets, and erythrocytes.
The isolated human basilar artery suspended in Kreb's solution contracts to 5-hydroxy-tryptamine, noradrenaline, and histamine, which stimulate specific receptors. Normal human serum contains an unidentified contractile substance, and erythrocytes relax the artery. Serum and erythrocytes potentiate 5-HT contractions. This preparation is suitable for studying vasoactive substances released during vasospasm after subarachnoid haemorrhage.
Comments on the combined translabyrinthine-transtentorial approach for acoustic neuroma.
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The retinal manifestations of fat embolism.
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Studies in cervical spondylotic myelopathy. I. Movement of the cervical roots, dura and cord, and their relation to the course of the extrathecal roots.
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Studies in cervical spondylotic myelopathy. 3. Some functional effects of operations for cervical spondylotic myelopathy.
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Studies in cervical spondylotic myelopathy. II. The movement and contour of the spine in relation to the neural complications of cervical spondylosis.
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Immune complexes in experimental syphilis: a methodologic evaluation.
Sustained antigenic stimulation following intravenous infection of rabbits with Treponema pallidum results in antibody responses and the formation of immune complexes. Complexes in greater than 300 sera from normal rabbits and from animals with experimental syphilis were measured by Raji cell and polyethylene glycol-complement consumption assays. Profound increases in both the incidence and levels of immune complexes were seen between the third and seventh weeks of infection. Single radial immunodiffusion studies revealed moderate increases in immunoglobulin levels and depression of C3 levels during the third and fourth weeks of infection. Penicillin treatment was followed by normalization of C3 levels and clearance of immune complexes. Lower levels of complexes in the sera of intradermally infected rabbits and the absence of immune complexes in intratesticularly infected animals suggest that immune complexes in the circulation may be related to the extent and severity of cutaneous involvement.
Pharmacokinetics of BSH in patients with glioma.
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