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Biomedical subjects

C Azzolini

Publications and source records attributed to C Azzolini.

41 records · Page 3Linked to original sources

OCT images and surgery of juvenile Macular retinoschisis.

We describe three cases of X-linked juvenile retinoschisis confined to the posterior pole of the eye, one of which surgically treated. In the first two cases, in vivo optical coherence tomography (OCT) had revealed a cleavage plane in both nerve fiber and outer retinal layers. In the two similar operated eyes of the third case, postoperative OCT had revealed the disappearance of macular schisis in the eye with good recovery of visual function after surgery. On the contrary, it had revealed a persistent splitting of the retina in the other eye, not clinically visible, which explained the poor recovery of visual function after surgery. In cases with progressive worsening of macular involvement in X-linked juvenile retinoschisis, highly accurate surgery may be considered, and the pre- and postsurgical OCT monitor of these patients is indicated.

Adolescent↗

Optical coherence tomography in idiopathic epiretinal macular membrane surgery.

PURPOSE: To evaluate the usefulness of Optical Coherence Tomography (OCT) images for surgical indication, intraoperative management and postoperative outcome of patients with idiopathic epiretinal macular membrane (IEMM). METHODS: 28 selected eyes underwent surgery for removal of IEMM. The patients' mean age was 57.3 years. The macular region and the IEMMs were studied before and after surgery using OCT, slit-lamp biomicroscopy and fundus photography. The mean postoperative follow-up was 6.2 months (range 1.3-14). RESULTS: Preoperatively, in 12 of the 28 eyes (42.9%) only the OCT images revealed IEMM partially separated from the macula, with tractional focal point(s) of attachment to the macular region. In the other 16 eyes (57.1%) in which IEMMs were totally adherent to the macular region, the membranes were barely visible by OCT in 13 eyes and not visible in three. Intraoperatively, the surgeon was guided in the peeling procedures. A significant correlation (p < 0.001) was found between visual acuity and macular thickness before surgery and at the end of the postoperative follow-up. CONCLUSIONS: OCT images provide very useful information for the surgical indication, intraoperative management and postoperative outcome of patients with IEMM.

Adolescent↗

Myofasciocutaneous expansion in the tegumentary rehabilitation of the amputation stump.

In post-traumatic amputations, in particular in leg amputations, the presence of an unstable scar or of ulcerous areas that are difficult to heal in the site of the amputation stump constitutes a repair problem that is not easily solved. In this specific field of reconstruction skin expansion has earned significant agreement, and is even considered to be a safe and reliable method for the surgical rehabilitation of the amputation stump, allowing us to obtain high-quality tegumentary covering, with no excessive thickness, that adapts well to the prosthesis and to the underlying skeleton, and that is characterized by good sensitivity of protection. Tegumentary amplification may, in some cases, also become myocutaneous, allowing us to obtain more tissue thickness for protection in patients submitted to chronic loading that lasts longer and in those with thin teguments, in which traditional expansion could determine excessive narrowing of the tegumentary covering, following atrophy caused by compression of the subcutaneous adipose tissue.

Accidents, Traffic↗

[A nasal reconstruction via the expansion of the tissue].

The techniques that offer the best results in total nasal reconstruction are those that use frontal skin. Even if traditional procedures meet most of the reconstructive needs, they are often limited by the size of the tissues to be transplanted and by the scarring they leave in the donor area. The stiffness and scarce pliability of the frontal skin hinder fine modelling of the alae, of the columella and of the nasal tip. Expanded forehead flaps to day offer a substantial advantage. In the period from 1986 to 1991 total nasal reconstruction was performed in 12 patients (4 males and 8 females). Their ages ranged from 4 to 69 years. Four patients presented a recurrence of a basal cell carcinoma, 1 patient presented a trichoepithelioma. In 3 cases an arteriovenous vascular malformation was present, in 1 there were radiodermatitic lesions while in another 3 cases there was extensive scarring. In all cases a rectangular skin expander without base and with a remote filling port was used. The nominal volume ranged from 100 cc to 260 cc. All expanders were introduced through a vertical hair incision in the subgaleal plane, except in 1 case in which it was placed over the frontal muscle. The mean time of expansion was 79 day. The mean volume at the end of the expansion was 283 cc. The results obtained are presented and the advantages of the technique are exposed. These are: 1) the possibility of obtaining forehead flaps wide enough to cover large defects, 2) the direct closure of the donor area even if large flaps are raised, and 3) the improved pliability of the expanded frontal skin. A minor complication present in all the patients treated was moderate pain during inflation of the expander, easily controlled with common analgesics. A bony crest was frequently observed around the base of the skin expander which, however, was easily removed with a curette. Only in one case was a major complication observed; that of a preoperative infection necessitating removal of the expander, which was reapplied a few months later in order to complete the initial reconstructive program.

Adolescent↗