Search PubMedSearch

Biomedical subjects

C Arseni

Publications and source records attributed to C Arseni.

At least 19 recordsLinked to original sources

Giant sacro-coccygeal teratoma. Case report.

A case is presented, of a giant teratoma in the sacro-coccygeal region, in a two-year old child. Surgery was performed in two successive stages, one month apart, under CT-scan control. Exeresis of the teratoma was complete. The authors stress the very large volume of the tumor, that extended in the pre-sacral area, and the fact that complete exeresis was mandatory. Eight months after surgery the postoperative evolution was satisfactory. The importance of CT-scans for the postoperative control is stressed, in cases of teratomas extending in the pre-sacral retroperitoneal area.

Child, Preschool

Cerebral abscesses secondary to otorhinolaryngological infections. A study of 386 cases.

A study is presented, of adjacent cerebral abscesses secondary to otorhinolaryngological infections. A total of 386 patients were included. According to frequency, and in relation to the adjacent septic focus the cerebral abscesses were classified as: otogenic--334 cases (86.5%); rhinogenic--47 cases (12.2%); tonsillary--5 cases (1.3%). These abscesses had similar characteristics: they occurred with the highest frequency in the second and the third decade of life, had a higher incidence in males, the otorhinolaryngologic infection had a chronic course with frequent recidives, propagation of the infection from the original focus occurred by continuity or through the venous system, and the clinical picture was marked by symptoms of local and general infection, by meningeal manifestation, and frequently by altered consciousness (somnolence, confusion). Surgical treatment, next to other therapeutic measures (administration of antibiotics, anti-inflammatory drugs, and intensive care) was aimed at improving the vital prognosis. The postoperative mortality was 23.8%. It was also aimed at increasing the functional recovery rate. Neuropsychical sequellae were noted in 54.9% of all cases. After surgery for the cerebral abscess attempts were made at removing the septic focus, preventing any additional risk of cerebral seeding.

Bacterial Infections

Focal epileptic seizures ipsilateral to the tumour.

The authors report on six cases of cerebral tumours: three astrocytomas (two temporal and one frontal), two meningiomas (one parietal and one frontal), and a metastasis with a temporal location causing sensory-motor epileptic seizures ipsilateral to the lesion. The discussion includes comments on the pathogenesis of these manifestations viewed in the light of experimental and electrophysiological data, and on the hypotheses of the "mirror focus", irritation of the supplementary motor and secondary somato-sensory areas, compression of the opposite hemisphere, and possible absence of decussation of the sensory-motor pathways. The false localization suggested by this type of paroxysmal senzures and their rare clinical occurrence is emphasized.

Adult

Influence of temporal lobe lesions on photic-evoked responses in occipital visual areas.

In 20 patients with temporal lobe lesions and 10 controls, the averaged photic-evoked responses (APERs) and their dispersion pattern (DP) were investigated in inion-vertex-lead and bilaterally in inion-parietal leads (I-P3 and I-P4). The patients with temporal lobe lesions, regardless of lesion location in temporal areas, displayed either absence of APER (the whole APER or only the initial components) or a latency increase without amplitude changes. The DP was generally abnormal. The role of the temporal lobe in the organization of APER in visual areas is discussed.

Adult

Nelson's tumour--two case reports.

Two cases of tumours of the pituitary gland, occuring in patients after bilateral adrenalectomy for Cushing's syndrome, were admitted to the Clinic and operated on during the period 1974 to 1976. The clinical and laboratory data are compared to those of similar, published cases. The aetiology is discussed in the light of recent neuroendocrine investigations.

Adenoma, Chromophobe

Spinal dissemination following operation on cerebral oligodendroglioma.

This paper concerns two cases of cerebral oligodendroglioma (intraventricular in one case, right temporal in the other), with spinal dissemination (cervical and upper thoracic respectively), manifested clinically 2 years and 14 months respectively after removal of the cerebral tumour. Anatomical examination confirmed the diagnosis of disseminated oligodendroglioma in the leptomeninges in both cases and also in the parenchyma in the second case.

Adult

Haematological aspects of hypophyseal tumours.

This paper is devoted to the study of anaemia in patients with hypophyseal tumours. Anaemia with a red blood cell count of 2.4 million/mm3 to 3.9 million/mm3 was found in 60 of 280 patients (21.7%) with hypophyseal tumours; 52 of the 60 patients were operated on. Similar changes were observed in 25 of 60 cases (41.7%) of craniopharyngioma. Apart from anaemia and a low haemoglobin some of the patients also had anisocytosis, anisochromia, leucocytosis, and haemolytic shock.

Adolescent

Spinal dermoid tumours.

The present work is a detailed analysis of 12 cases of spinal dermoid tumours operated on between 1935 and 1976. Of these 11 were medullary (3 intramedullary and 8 subdural extramedullary), representing an incidence of 0-80% of medullary tumours, and 1 was an extraspinal coccygeal tumour. Most of the tumours were located in the spinal canal and conus. Good results were obtained following total ablation in 7 cases and partial removal of the tumour in 5 cases.

Adolescent

Cranial eosinophilic granuloma.

Investigations were carried out on 27 cases of cranial eosinophilic granuloma: 16 males (59%) and 11 females (41%). The mean age was 25 years, the extremes being 2 years and 65 years. The location in 21 cases (80%) was exclusively in the calvarium (9 frontal, 8 parietal, three occipital and 1 temporal), orbital in two cases, fronto-orbital one case, base of the skull in the left parasellar region one case, left frontal subdural with chronic subdural haematoma one case and one case left occipital and petrosal bone. All the cases were diagnosed histologically. In 18 cases the tumour was removed at operation. Recurrences occurred in four of these cases (15%), three of whom died (11-5%). Four of the patients received steroid therapy and four steroid therapy combined with X-ray therapy. The evolution was favourable in all these cases.

Adolescent

Logorrhea syndrome with hyperkinesia.

The present paper reports on 13 cases of logorrhea syndrome with or without hyperkinesia, or hyperkinesia without logorrhea, with lesions at various levels of the nervous system. Lesions of the ascending reticular inhibitory system are incriminated. The mechanism producing this syndrome is discussed.

Brain Diseases

Cerebral dermoid tumours.

Four cases of cerebral dermoid tumour with an intraventricular, occipital and sellar location are reported, representing 0.04% of the verified cerebral tumours in the authors' statistics. A recurrence occurred after one year in the first case of intraventricular dermoid tumour; after the second operation aseptic meningitis developed and the patient died. In the second case microscopic examination revealed aspects of malignant transformation of the tumour. The symptoms did not differ from those of other cerebral tumours. Operations should be radical whenever possible, avoiding dispersion of the tumour contents in order to prevent a recurrence or aseptic meningitis.

Adult

Visual evoked responses and their dispersion pattern in frontal lobe tumours.

In patients with frontal lobe tumours the averaged visual evoked responses (AVER) and their dispersion pattern (DP) in visual areas were investigated before and at different periods after operation. Important changes in AVER (in amplitude and latency) were found in the patients with tumours on the midline or in one of the frontal lobes. The DP was abnormal in all the cases. There was no relation to visual acuity, tumour location and existance of intracranial hypertension. After operation, despite the clinical improvement, the alterations of AVERs or DPs were very marked and in some cases became even more important than before. The role of the frontal lobe in the organization of the responses to peripheral stimuli in the visual areas is discussed.

Adult

Encephalopathy subsequent to accidental poisoning with chlorpromazine.

A cerebral biopsy performed in an infant 9 months after accidental poisoning with chlorpromazine was studied. Light microscopy disclosed necrosing encephalopathy, while electron microscopy showed neuronal, glial, myelinic and vascular lesions. The findings in the present study suggest that the various neurologic syndromes appearing in cases of prolonged treatment with neuroleptic drugs and persisting after cessation of therapy would be due to consequent occurrence, in specific areas, of some irreversible cerebral lesions.

Capillaries

Supratentorial dissemination of medulloblastomas.

The present paper reports on 13 cases of medulloblastoma with supratentorial dissemination. With reference of these cases the authors discuss the pathogenetic probabilities of the dissemination of brain tumors, their evidence and treatment, emphasizing the importance of cerebral scintigraphy formed periodically in all patients previously operated of medulloblastoma. When dissemination is detected radiotherapy may give good results. If the symptomatology is very accentuated the secondary supratentorial tumour has to be removed.

Adolescent

Intracranial ganglioneuromas in children.

Two cases of tumours of the sellar and suprasellar region in children, manifested clinically by visual and endocrine disturbances, are reported. In both cases surgical removal of the intracranial tumour was performed. The histological diagnosis was central ganglioneuroma, an extremely rare tumour in children. Also worthy of note was the altogether exceptional location in these children of central ganglioneuromas in the sellar and suprasellar region.

Brain Neoplasms

[Giant bilateral parasagittal fronto-parietal hyperostosing meningioma. Clinico-therapeutic considerations in a particular case].

A case of giant bilateral parasagittal fronto-parietal hyperostosing meningioma is discussed. Its weight was 910 gr., it was removed in two operations and finally an acrilic cranioplasty was done. The patient pas followed for 24 years and no neurological sequelae have been found. He is still working as a farmer. The author reviews the relevant literature and discusses the differential diagnosis.

Acrylic Resins