The intracellular buffering (delta HCO3-/delta pH) in rats is lowest in skeletal muscle, intermediate in the diaphragm and highest in cardiac muscle. In the hypertrophic heart due to aortic constriction or to the Goldblatt mechanism the buffer value increases markedly during the first weeks, but returns to normal or even subnormal values during stable hypertrophy. There is an electrochemical disequilibrium for hydrogen ions caused by an active transport of ions across the cell membrane, which is possibly correlated to the myocardial activity.

Animals↗

PubMedDate not supplied

[Surgical treatment of unstable, therapy-resistant and painful lumbosacral joints by distracting decompressive posterolateral spondylodesis over the divided sacral bar according to Zielke's method (author's transl)].

Here the procedure of the distracting decompressive fusion over the divided sacral bar which Zielke developed 8 years ago is being described. This procedure was applied in over 150 cases. In a follow-up only one pseudarthrosis was found in the area of L5/S1. 70% of the previously pensioned patients could at least be partially rehabilitated. 32 patients were asked of their opinion with a questionnaire. Only 2 patients (6%) assessed the operation results with "bad". Indication is in all instabilities of the lumbosacral joint. The problem of the multi-operated back can be largely solved through the possibilities of this procedure.

Adolescent↗