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Biomedical subjects

C A Weiss

Publications and source records attributed to C A Weiss.

27 records · Page 2Linked to original sources

Clinical aspects and surgical treatment of hyperadrenocorticism in the domestic ferret: 94 cases (1994-1996).

The signalment, clinical findings, laboratory values, and histopathological results of 96 ferrets with signs (i.e., bilaterally symmetrical alopecia, return to male sexual behavior, or an enlarged vulva) suggestive of hyperadrenocorticism were evaluated retrospectively. Of these 96 ferrets, 94 (98%) were diagnosed with hyperadrenocorticism histologically. Treatment consisted of unilateral adrenalectomy for unilateral tumors (84%) and subtotal bilateral adrenalectomy for bilateral adrenal tumors (16%). The histopathological diagnosis included nodular hyperplasia (56%), adrenocortical carcinoma (26%), and adrenocortical adenoma (16%). Common concurrent diseases included splenomegaly (87%), islet-cell tumor (27%), and cardiomyopathy (10%).

Adenoma↗

Insulinoma in the ferret: clinical findings and treatment comparison of 66 cases.

The clinical signs and surgical findings were reported for 66 ferrets with insulinomas confirmed histologically. All of the ferrets were treated with one of three modalities, and disease-free intervals and survival times were gathered to determine the most effective treatment. The three treatment groups included 10 ferrets treated medically, 27 ferrets treated with pancreatic nodulectomy, and 29 ferrets treated with pancreatic nodulectomy combined with a partial pancreatectomy. The mean disease-free intervals for each group were 22, 234, and 365 days, respectively. The mean survival times for each group were 186, 456, and 668 days, respectively. Based upon the data, recommendations were made for treating insulinoma in the ferret.

Animals↗

The role of epidural cortisone injection in the treatment of diskogenic low back pain.

Primary treatment by epidural injection of cortisone in patients suffering from characteristic diskogenic disease was helpful in 82% of patients. However, when given after three months of back pain, after previous laminectomies, and in patients actually suffering from an unstable spine which required fusion, epidural injections were of little value. No complications resulted from the injection and there was no compelling evidence to indicate that the placement of the needle by radiologic means is necessary. Because of these benefits and the fact that all of the patients were candidates for laminectomy, the use of this injection prior to surgery should be considered. The number of injections that may reasonably be given, the degree to which the patient should become asymptomatic, and the period of time during which relief continues remain to be clarified by a larger and more sustained study.

Adolescent↗

Femoral stem failure and ectopic bone formation in total hip arthropalsty: four case reports.

In 4 cases of fracture of the femoral stem in total hip arthroplasty (THA), 3 were preceded by clinical and radiographic evidence of loosening and the last was not. Each developed a significant amount of ectopic bone. Stem failure in THA is a continuum progressing in some cases from ectopic bone formation and calcar resorption to stem loosening. An association between ectopic ossification and stem loosening is determined by grading the quantity of new bone not only by the amount but also by its spatial relationship with the implant. Observation on a large number of cases by the method of DeLee, Ferrari, and Charnley is required to prove or disprove the effect of ectopic bone on stem failure. In any case, patients who develop ectopic bone should be restricted in their activities.

Aged↗

Hip rating scales: a clinical analysis.

Thirty patients were graded both before and after total hip replacement according to several hip-rating scales and the results compared. This comparison shows that a scale which keeps the various parameters of pain, motion and function, separating rather than integrating them, is more useful to the surgeon. Subgrading the patients into A, B and C is essential for functional comparisons.

Arthritis, Rheumatoid↗

Subluxation of the tibialis posterior, a complication of tarsal tunnel decompression: a case report.

In a 16-year-old girl, anterior subluxation of the posterior tibial tendon repeatedly occurred after release of the flexor retinaculum for tarsal tunnel syndrome. The symptoms resulting from this subluxation were more disabling than the original complaint. A reconstructive procedure eliminated the subluxation but did not cause recurrence of the tarsal tunnel syndrome. Though this complication is rare, it suggests that opening of the retinaculum for decompression of the tarsal tunnel should be done as far posteriorly as possible, so that the remaining retinaculum can act as a flap to prevent subsequent anterior subluxation of the tendon(s).

Adolescent↗

Stability of the Giliberty bipolar hip: report of three cases.

The Giliberty Bipolar Hip Prosthesis consists of an unbonded acetabular cup which snap-fits over the head of the femoral prosthesis. Because of the free movement permitted at the cup-pelvic junction as well as at the snap-fit interface, there has been a great deal of concern over the potential for dislocation. Three patients in whom this unit was implanted sustained significant skeletal trauma subsequent to surgery. None of them dislocated. In each case the prosthetic head was known to be in a relatively vertical orientation with respect to the transverse axis of the pelvis prior to the injury. In 2 of the 3 cases radiographically identifiable movement of the cup was present before and after the injury. These observations suggest that the persistently mobile, vertically positioned unbonded cup remain stable despite the stress of significant trauma. It is probable that the potential for cup movement, even where on the X-ray it appears to have stopped, acts as a safety valve in absorbing force that might otherwise dislocate the hip or cause fractures of the femur or the pelvis.

Aged↗