Biomedical subjects
C A Quick
Publications and source records attributed to C A Quick.
Multiple bilateral orbital abscesses secondary to nasal furunculosis.
Orbital inflammation secondary to sinus inflammation is a well known entity and has been widely reported. However, nasal furunculosis resulting in orbital inflammation is a rare occurrence. We present a case of a 2-year-old boy who developed multiple bilateral orbital abscesses secondary to nasal furunculosis. To our knowledge such a case has not been reported before.
Genetic variation among papillomaviruses.
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Giant cell tumors of the maxilla in children.
Three types of giant cell lesions occur in the facial skeleton; namely, giant cell reparative granuloma, Brown tumor of hyperparathyroidism, and true giant cell tumor -- osteoclastoma preferably called giant cell neoplasm. An appraisal of the clinical course biochemical laboratory data, radiographic appearance, and histological features are all necessary to distinguish between these varieties. Differentiation is a prerequisite to treatment because the management differs in each lesion. Three case reports illustrate these features. The important considerations of facial growth following surgery to the facial skeleton of a child are discussed. Long-term observation is imperative.
Frequency and significance of epithelial atypia in laryngeal papillomatosis.
The clinical records and microscopic sections from 32 patients were reviewed in an attempt to correlate histopathologic features with clinical behavior. Three general clinical groups were identified on the basis of recurrence rates and extent of papillomatosis. In those lesions with the highest frequency of recurrences, epithelial atypia tended to be most pronounced. Although some of the lesions were quite disturbing, there was no evidence of invasive carcinoma. It remains unknown to date whether these cytologic abnormalities represent a neoplastic alteration or possibly atypia on the basis of rapid, but benign, cellular turnover. Further studies at our center and other institutions are necessary to test the proposed classification which, if validated, would provide a means of predicting the course of the disease and efficacy of the chosen management in these difficult cases.
Arytenoid dislocation.
The reported incidence of arytenoid cartilage dislocation is low. This may be due to the wide range and orientation of motion allowed by the cricoarytenoid articulation and the laxity of its joint capsule. In two previously reported instances of arytenoid dislocation, the authors have suggested that endotracheal intubation is generally not sufficient to cause dislocation of an arytenoid cartilage, but that, in their cases, a predisposing factor had set the occasion for dislocation. In this communication, three cases of arytenoid cartilage dislocation, which each followed a single instance of endotracheal intubation are presented. In all three cases, painful swallowing was the main presenting symptom. Clinical features that differentiate arytenoid cartilage dislocation from vocal cord paresis are summarized. Early reduction of the dislocation, while the patient is under local anesthesia, is recommended, and the techniques are described in detail.
The use of revascularized ileocolic autografts for primary repair after pharyngolaryngoesophagectomy.
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Experimental temporal bone histopathology in rats deprived of dietary retinol and maintained with supplemental retinoic acid.
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The etiology of laryngeal papillomatosis.
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Bronchoscopy and lavage in management of pulmonary complications of cystic fibrosis.
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Mucoceles with intracranial and extracranial extensions. Report of two cases.
Two cases of unusual childhood mucocele are presented. These serve to illustrate the great potential these lesions have for slow, insidious development and insinuation of themselves into regions of the head and face where they are difficult to remove surgically. A description of the staged surgical excision is presented to emphasize the importance of radical removal of these benign lesions.
Ranula and the sublingual salivary glands.
The term "ranula" is poorly understood and is frequently applied to a variety of cystic structures in the head and neck. Ranulas classically are cysts of salivary gland origin, usually the sublingual glands, of which two varieties are described: a simple, epithelial lined cyst resulting from ductal obstruction, and a pseudocyst without epithelial lining resulting from extravasation of saliva that dissects through the tissue planes of the neck and may appear as a neck mass. Four cases are presented that illustrate the difficulties in diagnosis; treatment consists of meticulous dissection of the thin-walled sac in continuity with the excision of the sublingual glands that are the origin of these lesions.
Temporal bone histopathology in experimental hypovitaminosis A.
Twenty-five years ago hearing loss was observed in some subjects during a comprehensive study of the effects of hypovitaminosis A on human volunteers. Experimental studies documenting histopathological changes in the temporal bone due to hypovitaminosis A are conflicting. Even the recent textbooks of otolaryngology and physiology make no mention of a role of vitamin A in the ear. To explore the role of vitamin A in the ear adult and weanling rats maintained on a diet totally lacking vitamin A were sacrificed at intervals. Their temporal bones were examined with the light microscope. After six weeks on a vitamin A free diet weanling rats showed hypertrophy of the periostial portions of the otic capsule. At 16 weeks a narrowing of the internal auditory canal due to bony exostoses was present. The neuroepithelia of the cochlea and the vestibular apparatus were histologically normal even in the longest surfiving animals. Adult rats maintained on a vitamin A free diet showed minimal thickening of the bone adjacent to the internal auditory meatus. The cochlea and the vestibular appartus in these animals remained normal throughout the 28-week experiment. Although we have demonstrated marked abnormalities of the otic capsule in hypovitaminosis A, our results do not support those of some earlier investigators who reported that atrophy of the cochlear and vestibular neuroepithelium occurred in the absence of dietary vitamin A.
Comparison of penicillin and trimethoprim-sulfamethoxazole in the treatment of ear, nose and throat infections.
A double-blind trial of penicillin and the combination trimethoprim-sulfamethoxazole was undertaken in adult patients with active infection of the ears, nose or throat. The results indicated that the drug trimethoprim-sulfamethoxazole was as effective as penicillin in achieving clinical improvement and showed a broader spectrum than penicillin the the elimination of pathogenic organisms. The difficulties in obtaining positive cultures that were reflective of the clinical condition are described.
Styloid process neuralgia: myth or fact.
Five cases of enlogated styloid processes sent in a 12-month period prompted a review of this subject and a reevaluation of the condition as it relates to other neuralgias of the head and neck. We review the head and neck pain syndromes and offer diagnostic criteria that will aid in the differential diagnosis and will facilitate appropriate management.
Deafness and renal failure due to potassium bromate poisoning.
Several substances are known to have a profound effect on both the kidney and the inner ear. The aminoglycoside antibiotics are toxic to both of these organs. Ethacrinic acid and furosemide affect transport mechanisms in the loop of Henle as well as the inner ear. In addition, studies have suggested antigenic similarities between the stria vascularis of the cochlea and the renal tubules. This report of potassium bromate poisoning and its resultant deafness and renal failure further emphasizes the curious relationship between these two organ systems.
The role of otolaryngology in primary care practice. Report of a survey.
A survey was conducted to assess how family practitioners rated certain knowledge skills and procedures in the field of otolaryngology. A questionnaire was designed as the instrument of the survey, and family practitioners were asked to complete the questionnaire based entirely on their experience in practice. The results of the survey showed that the practitioners considered that the majority (64%) of the items ranged from necessary to imperative. A highly consistent response was obtained. We discuss implications for curriculum design based on such surveys.