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Biomedical subjects

C A Phillips

Publications and source records attributed to C A Phillips.

176 records · Page 10Linked to original sources
PubMed1965

Enteric virus isolation in different cell cultures.

The need for establishing an optimum tissue culture cell line for isolation of enteric viruses prompted a comparative study of cell lines for the isolation of enteric viruses from rectal swab specimens. The viruses isolated included all three types of poliovirus, 12 types of echovirus, seven types of group A and two of group B coxsackievirus, 24 strains of adenovirus, and eight untyped agents which probably represent new enteroviruses. One hundred positive isolations were made from 387 rectal swab specimens; 86 were obtained in human kidney cultures. This was almost twice the number obtained with monkey kidney and more than one-and-a-half times that obtained with human lung cells (WI-38). A diploid human epithelial cell line (Attleson) was tested and was found to be inferior to both monkey kidney and WI-38 cells for enteric viruses. Human kidney cells were particularly useful for group A coxsackieviruses and adenoviruses.

Enterovirus↗
PubMedDate not supplied

Speech during partial seizures: intracranial EEG correlates.

Vocalization during a seizure may help predict the location of seizure onset or identify structures ultimately involved in the seizure. Spontaneous vocalization during seizures was studied retrospectively in 22 patients with refractory complex partial seizures evaluated with bilateral intracranial electrodes. Of 22 patients, 12 vocalized during seizures. Seizures were as likely to originate from language-dominant (6/12) as from language-nondominant mesial temporal cortex (6/12). Fluent speech frequently occurred as seizure activity was recorded from language-dominant temporal lobe neocortex (6/12 seizures). Of the patients with well-localized seizure onsets who did not speak (6/10), seizures arose from both language-dominant and -nondominant mesial temporal cortex. We conclude that the presence or absence of vocalizations during a seizure does not reliably indicate the anatomic regions in which the seizure begins or spreads.

Adult↗