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Biomedical subjects

C A Morris

Publications and source records attributed to C A Morris.

At least 145 records · Page 8Linked to original sources
PubMed1974

Antibodies to Candida albicans in hospital patients with and without spinal injury and in normal men and women.

The presence of serum agglutinins and precipitins to Candida albicans in men and women who had impaired bladder function following spinal injury is compared with that in other patients in hospital and in apparently fit men and women. Antibody levels which have commonly been regarded as significant were found in 35 of 76 patients who had urinary candidiasis; in 10 of 52 patients who had spinal injury without urinary candidiasis; in eight of 57 patients who had neither of these conditions, and in nine of 191 normal men and women. Observations are made on the antigens involved in these reactions and on the need for standardization of both reagents and techniques.

Adult↗
PubMed1973

The post-mortem diagnosis of influenzal infection by fluorescent IgG, IgA and IgM antibody studies on necropsy blood.

Necropsy blood from cases diagnosed as dying from influenza A was examined for specific antibody in the IgG, IgA and IgM fractions and a specific diagnosis of recent infection was made if either IgM or IgA antibody and low titres of IgG antibody were found. By these criteria a diagnostic rate of 77% was found in those cases from whom no virus was isolated. The use of infected cell monolayers grown on polytetrafluoroethylene-coated slides gave a simple method of carrying out these antibody assays, and the use of necropsy blood did not require any special methods of transport of specimens to the virus laboratory.

Aged↗
PubMed1973

Tuberculoid lymphadenitis due to Mycobacterium chelonei.

An 8-year-old boy developed cervical lymphadenitis four months after an injection of dental anaesthetic. Histology of the lymphatic tissue showed a tuberculoid granulomatous reaction with scanty acid-fast bacilli. Mycobacterium chelonei was isolated in pure culture (NCTC 10882). The patient showed specific skin hypersensitivity to an extract of M. chelonei, but not to that of M. ranae. This is thought to be the first recorded case of lymphadenitis in man caused by M. chelonei; it adds another possibility to be considered in the differential diagnosis of ;a lump in the neck'.

Child↗
PubMed1972

Absence of compensatory renal hypertrophy in baboons.

1. The weights of kidneys of fifteen adolescent and forty-six adult male baboons were estimated. In contrast with what has been described in other mammals, in the majority of baboons (thirty-nine out of fifty-seven) the left kidney was heavier than the right.2. The medulla/cortex ratio was of the order of 1.8. The maximum urinary concentration, after 36 hr of food and water deprivation, averaged 1050 +/- 80 m-osmole/kg H(2)O.3. Unilateral nephrectomy was performed in twelve baboons with body weight ranging from 5 to 14 kg. In six animals, the left kidney was removed and the right kidney in the others.4. In two baboons, the left kidney was transplanted to the left iliac artery and vein, the ureters being left intact. After a few weeks, the right kidney was taken out, and the animals were kept under observation, one for a further 3 months and the other for a further 4 months.5. In none of the animals, whether after simple unilateral nephrectomy or after unilateral nephrectomy following transplant of one kidney, did the renoprival kidney show any significant enlargement.6. After unilateral nephrectomy, the health of the animals remained excellent, all the baboons increasing in body weight. The ability to concentrate urine by the renoprival kidney was not impaired.7. In contrast with what has been described in mice and rats, in unilaterally nephrectomized baboons no significant changes in the concentration of either RNA or DNA in renal cortex and medulla of the contralateral kidney were observed.8. After unilateral nephrectomy in baboons, there was a marked increase of oxygen uptake in slices from the cortex, but not from the medulla. In contrast with what had been observed in rats where the enhanced rate of oxygen uptake returned to pre-operative values, in baboons no decrease was observed, the rate of oxygen uptake remaining high during the whole period of observation.9. In the limit of time of observation (maximum 4 months) there was no evidence that unilateral nephrectomy resulted in compensatory hypertrophy of the contralateral kidney.

Animals↗
PubMed1971

Seasonal variation of streptococcal vulvo-vaginitis in an urban community.

A study was made of patients investigated by general practitioners. Over a three-year period Streptococcus pyogenes (group A) was isolated most commonly from vaginal and vulval swabs collected in the winter. The serotypes of strains indicate that some had probably been derived from the skin and others from the respiratory tract. The two sources are thought to have masked a consistent, but not obvious, seasonal variation in streptococcal vulvo-vaginitis acquired usually from streptococcal infections of the respiratory tract in winter and from those of the skin in summer.

Adult↗