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Biomedical subjects

C A Moes

Publications and source records attributed to C A Moes.

At least 37 records · Page 2Linked to original sources

Congenital aortico-right atrial communications. The dilemma of differentiation from coronary-cameral fistula.

Four cases of an unusual form of aortico-right atrial communication are described. All patients were asymptomatic but had an atypical continuous murmur on examination. A distinctive appearance was noted on the angiograms, with a large tortuous tunnel noted superior to the left sinus of Valsalva, passing posterior to the aortic root before terminating near the right atrial-superior vena caval junction. This structure was readily identified by two-dimensional echocardiography. The defect was successfully closed surgically in three of four patients. The presence of normal major coronary arteries and absence of any small myocardial coronary branches from the tunnel argues against the structure being a coronary-cameral fistula and supports the diagnosis of aortico-right atrial tunnel.

Adolescent↗

Synthetic patch angioplasty for repair of coarctation of the aorta: experience with aneurysm formation.

Patch graft angioplasty is an accepted technique for the repair of some forms of coarctation and for recoarctation. Since 1970, 63 patients at our institution underwent 65 operations for repair of coarctation (ages 3 days to 32 years); in 27 it was the initial operation and 38 needed surgery for recoarctation. Average follow-up was 3.5 years (range 3 months to 14 years). There was one death, 20 patients with persistent hypertension, and eight patients with a persistent arm/leg pressure gradient (14 to 30 mm Hg at rest). Five patients required reoperation, two for recoarctation and three for aneurysm formation. The aneurysms were found on routine chest x-rays 3, 3.7, and 13.5 years after surgery. All aneurysms were repaired with left heart bypass in which a Dacron tube graft was used without complications. Synthetic patch angioplasty to repair coarctation was effective; however, aneurysm formation was a late complication in 5% of our patients. All patients undergoing patch repair should be followed on a yearly basis to allow early detection of aneurysms.

Adolescent↗

Double aortic arch with atretic right dorsal segment.

A patient in whom there was a double aortic arch with atresia of the right dorsal arch segment between the right subclavian artery and right ductus arteriosus is presented. The radiographic and aortographic features are demonstrated and the embryology is discussed.

Aorta, Thoracic↗

The investigation of abnormal pulmonary arteries in congenital heart disease.

Thorough investigation of the state of the pulmonary vascular bed is an important part of the preoperative assessment of patients with congenital heart disease. This article describes the imaging techniques applicable to anomalies and acquired changes of the pulmonary arteries, with emphasis on recent developments. The morphology and imaging of specific cardiovascular anomalies that involve the pulmonary arteries are described and illustrated.

Aortography↗

Bilateral ductus arteriosus (or remnant): an analysis of 27 patients.

Bilateral ductus arteriosus (DA) was clinically recognized in 27 patients studied angiographically from 1963 through May 1983. Distal bilateral DA origin of non-confluent pulmonary arteries was identified in 15 patients, ectopic or distal ductal origin of 1 pulmonary artery in 9 patients (5 without evidence of intracardiac disease) and isolation of the left subclavian artery in 3 (all 3 of whom had a right aortic arch). Other conditions reported to be associated with bilateral DA include interruption of the aortic arch with isolation of a subclavian artery, aortic atresia with interruption of the aortic arch in which bilateral DA supports the entire systemic circulation, bilateral DA complicating forms of congenitally malformed hearts other than those just stated, and, rarely, bilateral DA in isolation. Understanding the symmetric or paired nature of the primitive aortic arch system in the developing human heart facilitates recognition of the patterns of fourth and sixth arch anomalies seen with bilateral DA.

Angiography↗

Subclavian arterioplasty. Repair of coarctation of the aorta in the first year of life.

Between June, 1977, and December, 1982, 106 infants underwent subclavian flap arterioplasty for repair of coarctation of the aorta in the first year of life. This technique was utilized because of our previous experience with the end-to-end technique in 181 infants, in whom there was a recurrence rate of 42% at 5 years. The recurrence rate in 78 of the 81 survivors who have been followed up for a mean of 18.8 months +/- 15.9 months (standard error) is 17.3% at 1 year and 11.1% at 2 and 3 years postoperatively. The presence of associated disease affects mortality: only one death in 34 patients with isolated coarctation; three deaths in 24 with coarctation plus ventricular septal defect; and 21 deaths in 45 infants with coarctation and complex lesions. Our present approach in the group with coarctation plus ventricular septal defect is to repair the coarctation without banding the pulmonary artery and then to close the defect if the infant remains in failure. Operative survival was 13 of 13 without pulmonary artery banding and 11 of 14 with pulmonary artery banding.

Age Factors↗

Serous fluid leakage: a complication following the modified Blalock-Taussig shunt.

Polytetrafluoroethylene tubular grafts are useful in performing a systemic-to-pulmonary artery shunt (modified Blalock-Taussig). They allow a controlled-volume shunt, avoid kinking of the pulmonary artery, and preserve distal flow in the subclavian artery. Unfortunately, occasionally excessive serous fluid will drain through the interstices of the fabric. This results in excessive and prolonged chest tube drainage and/or localized seroma formation around the graft. This complication occurred in 26 children, an incidence of 18.8% of the 138 modified Blalock-Taussig operations. Repeat thoracotomy was required in four of these children--for evacuation of seroma mass in three and for relief of cardiac tamponade in one. Four other children required reinsertion of pleural or pericardial chest drains for excessive serous drainage persisting as long as 6 weeks after operation. Wrapping of the graft with silicone sheeting to facilitate subsequent takedown of the shunt led to seroma formation in five of nine children. We believe this practice should be abandoned. Excessive drainage of serous fluid through the interstices of PTFE grafts in almost 20% of our patients has compromised an otherwise satisfactory result of the modified Blalock-Taussig operation.

Blood Vessel Prosthesis↗

Pulmonary vein wedge angiography: indications, results, and surgical correlates in 25 patients.

Pulmonary vein wedge angiography was applied to 25 patients ranging in age from 4 months to 16 years. The indications for this technique include (1) determination of the presence or absence of central (intrapericardial or mediastinal) pulmonary arteries in patients with pulmonary atresia where standard anterograde injections of contrast medium do not demonstrate these, (2) determination of the patency and caliber of a nonvisualized pulmonary artery when there is distal "occlusion" by a systemic-to-pulmonary artery anastomosis, (3) determination of the patency and caliber of a nonvisualized pulmonary artery when previous pulmonary arterial banding has led to acquired pulmonary artery atresia, and (4) determination of the presence of a mediastinal pulmonary artery in patients with so-called isolated congenital unilateral absence of a pulmonary artery. Surgical correlates to the interpretation of pulmonary vein wedge angiograms are provided in 18 patients. The present data suggest that pulmonary vein wedge angiography is a safe technique that provides considerable information about (1) the caliber of the parenchymal pulmonary arteries, (2) their sizes at the hilum of the lung, and (3) the presence or absence of a mediastinal confluence of pulmonary arteries. This technique may also complement those anatomic findings derived from anterograde injection of contrast material in patients with pulmonary atresia of a congenital or acquired nature.

Adolescent↗

The atrioventricular junction in the univentricular heart: a two-dimensional echocardiographic analysis.

The atrioventricular junction of 40 patients with univentricular heart was evaluated by two-dimensional echocardiography. The apical 4 chamber view optimally imaged the atrioventricular junction, and allowed determination of the type of atrioventricular connection: double inlet, common atrioventricular orifice, and absent right or left atrioventricular connection. When double inlet to 1 ventricle was demonstrated, the 4 chamber view allowed immediate comparison of the form and function of the right and left atrioventricular valves. Because anomalies of the atrioventricular valves frequently complicate the univentricular heart, two-dimensional echocardiographic assessment is a most important adjunct to the preoperative investigation of these patients.

Adolescent↗

Right ventricular volume determinations in 18 patients with pulmonary atresia and intact ventricular septum. Analysis of factors influencing right ventricular growth.

Right ventricular growth was assessed angiocardiographically in 18 patients with pulmonary atresia, intact ventricular septum, and hypoplastic and hypertensive right ventricle. A variety of surgical procedures were performed. In only 12 patients (66.7%) was right ventricular-pulmonary artery continuity achieved (group 1). Nine of these 12 patients persisted with systemic or suprasystemic right ventricular pressures. Among the six patients in whom right ventricular-pulmonary artery continuity was not achieved (group 2), all maintained suprasystemic right ventricular pressures. Right ventricular growth was assessed in groups 1 and 2. The patients were also subdivided according to the qualitative degree of tricuspid regurgitation as determined angiocardiographically on right ventricular cineangiocardiograms at the preoperative catheter study. Right ventricular growth to normal levels as evidenced by change in right ventricular end-diastolic volume was rarely observed in group 2 patients. Among the four patients with severe tricuspid regurgitation and a large tricuspid valve, right ventricular growth to normal levels was achieved whether they were in group 1 or group 2. Right ventricular growth is thus predicated on numerous morphologic factors in these patients. However, reconstitution of right ventricular-pulmonary artery continuity and a nonobstructive tricuspid valve are probably two of the more important factors.

Aging↗

Aortic arch interruption with truncus arteriosus or aorticopulmonary septal defect.

Interruption of the aortic arch is commonly associated with cardiac malformations. The angiocardiographic appearance in the presence of coexistent truncus arteriosus or an aorticopulmonary septal defect may be very similar. Five patients with arch interruption, three of whom also had truncus arteriosus and two with an aorticopulmonary septal defect are analyzed and the pertinent literature reviewed. In the presence of a truncus arteriosus with arch interruption the aorta appears as an appendage arising anteriorly from a large "pulmonary trunk" with a single semilunar valve, whereas when there is an aorticopulmonary septal defect two separate great artery roots and two semilunar valves are visible. The angiographic features are best defined by a truncal root angiogram when there is a truncus arteriosus or by an aortic root angiogram in the presence of an aorticopulmonary fenestration.

Angiocardiography↗

Assessment of the cardiovascular system in conjoined thoracopagus twins.

The thoracoomphalopagus conjoined twins comprise 75% of all conjoined twins. In the assessment of the organ systems of the twins, the cardiovascular system is important since union of this system in the twins has occurred in 75% of the cases. Of the five cases reported here, two had separate hearts and vessels with a common pericardium only. Two twins were joined at the right atrial level. The fifth pair were connected at both atrial and ventricular levels. It has been suggested that the presence of two separate QRS complexes in the ECG indicates complete separation of the two hearts. Case 4 shows that even in the presence of atrial union, the existence of an atrioventricular block in one twin may produce a very slow heart rate, while the other twin may have a normal rate that will not influence the ventricular rate of the other. In our experience, angiocardiography has been the most useful diagnostic procedure.

Angiocardiography↗

Variation in the size and distensibility of the pulmonary arteries in d-transposition of the great arteries.

The relative size of the main pulmonary artery was determined from cineangiograms of 117 patients with d-transposition of the great arteries by calculating the ration between the diameters of the main pulmonary artery and aorta. The pulmonary artery was largest in patients with ventricular septal defect or patent ductus arteriosus, or both, because of increased pulmonary arterial pressure and flow. In patients with an intact ventricular septum or with left ventricular outflow tract obstruction, or both, the main pulmonary artery was approximately the size of the aorta. Two cases of d-transposition and gross dilatation of the main pulmonary artery and hypoplastic first branch pulmonary arteries are presented. In these cases the ratio between the diameters of the main pulmonary artery and aorta was greater than in any of the other 117 cases studied...

Blood Pressure↗

Echocardiographic assessment of bicuspid aortic valves. Angiographic and pathological correlates.

Aortic root echocardiograms were recorded from 89 patients whose aortic valves had also been adequately defined by selective angiography or viewed surgically or at autopsy. The eccentricity index (E.I.) of the aortic leaflets was measured at the onset of diastole and an E.I. of 1.3 or greater was taken as abnormal. Of 31 patients with isolated nonobstruced or mildly obstructed bicuspid aortic valves (7 viewed previously at valvotomy and 24 diagnosed radiologically) 23 (74%) had an abnormal E.I. Varying eccentricity occurred in some of these patients. Central leaflet echoes (E.I. of 1.0 to 1.25) were present in the other eight patients. All 14 patients with nonobstructed tricuspid aortic valves had central echoes. Additional multilayered diastolic echoes were found in patients with bicuspid aortic valves as well as in two patients with abnormal tricuspid aortic valves. The valves of 13 patients with aortic stenosis or incompetence were viewed surgically and the E.I. was abnormal in all patients with a bicuspid aortic valve in this group. Aortic leaflet echo findings were not diagnostically helpful in ten patients with tetralogy of Fallot, one of whom had a normal E.I. with a surgically confirmed bicuspid aortic valve. Of 21 patients with VSD only one had a bicuspid aortic valve but six had an abnormal E.I. This false positive sign was related to a high membranous VSD, sometimes with aortic valve prolapse. It is concluded that an E.I. of greater than or equal to 1.3 in the absence of an associated VSD is diagnostic of a bicuspid aortic valve and can be expected to be found in approximately three-quarters of subjects with this abnormality.

Adolescent↗

Selective aortic root angiography in the hypoplastic left heart syndrome.

Selective aortic root angiography was performed in 18 patients with the clinical diagnosis of hypoplastic left heart syndrome in order to allow more precise correlation with echocardiography. Aortic valve atresia and severe hypoplasia of the left heart chambers subsequently were substaniated at necropsy in each instance. Wide variation in the size and shape of the aortic root and ascending aorta was demonstrated angiographically in these patients. In some patients, despite aortic valve atresia, the dimensions of the aortic root and sinuses of Valsalva at angiography were almost normal. In addition, this technique allowed the demonstration of primitive vascular communications between the coronary artery and left ventricular cavity in 1 patient (coronary-cameral fistula). The realization that the aortic root may approach nearly normal size in some patients with the hypoplastic left heart syndrome is essential to the echocardiographic diagnosis of this disease and to the differential diagnosis from other cardiac and noncardiac causes of severe neonatal congestive heart failure.

Angiocardiography↗

Double outlet right ventricle (S,D,L) with subaortic ventricular septal defect and pulmonary stenosis. Report of six cases.

The clinical, hemodynamic, angiocardiographic and pathologic findings are presented in an infrequent but surgically correctable type of double outlet right ventricle. This study is based on six cases, one with autopsy confirmation. In all, the viscera and atria were in situs solitus (S). A ventricular d-loop was present (D). There was I-malposition of the great arteries, the aorta being to the left of, and anterior to, the pulmonary artery (L). Hence, this anomaly may conveniently be represented as double outlet right ventricle (S,D,L,). The ventricular septal defect to the ventricular septum. A bilateral conus was present beneath both the aortic and pulmonary valves, preventing any semilunar-atrioventricular fibrous continuity. The subpulmonary conus was poorly expanded, resulting in pulmonary infundibular and valvular (annular) stenosis. The clinical features were those of cyanosis, clubbing and accentuation of the second heart sound in the pulmonary area (related to aortic valve closure). There was a systolic ejection murmur along the upper left sternal border, related to pulmonary outflow tract stenosis. Selective right and left ventricular angiocardiography was diagnostic. Relatively early surgical correction is suggested to minimize the progression of pulmonary infundibular stenosis and to avoid acquired atresia. In this malformation, pulmonary outflow tract reconstruction is more difficult than in tetralogy of Fallot because of the rather posterior location of the pulmonary outflow tract, and because the right coronary artery crosses the stenotic pulmonary outflow tract in front of the pulmonary valve.

Angiocardiography↗