Biomedical subjects
Publications and source records attributed to C A Hansen.
Two useful approaches for the construction of dentures with a chromium alloy palate have been described. The phonetic considerations were recognized, and allowances were made for their vital role when determining the palatal contours of both the metal and plastic portions of the denture base.
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Twenty-five adolescent campers with insulin-dependent diabetes mellitus (IDDM) completed a Symptom Rating Checklist and estimated their blood glucose (BG) immediately before having their BG assessed four times daily for 11 days. Consistent relationships between BG and symptoms were not identified when the data were analyzed for the group as a whole. However, when each camper's data were analyzed separately, 23 of the 25 adolescents had at least one significant glycemia-symptom (G-S) correlation. Each camper seemed to have a unique G-S pattern; only one symptom (hungry) was significantly related to BG for more than half of the youngsters studied. Almost all of the significant G-S correlations were indicative of low rather than high BG. However, when asked, few campers were able to accurately identify which symptoms were reliably associated with low or high BG. In this study, different measures of BG estimation error led to different results. The percent of estimates +/- 20% of the actual BG value (55% in this study) was strongly influenced by the actual BG reading because higher BG values have larger accuracy ranges than lower BG concentrations. When estimated BG was simply subtracted from actual BG, under- and overestimates canceled each other out, resulting in an unusually small estimated error (5 mg/dl in this investigation). The absolute difference score ignores the direction of estimation error, but may more accurately reflect patients' average estimation error (68 mg/dl in this study). When actual and estimated BG values were correlated for the group as a whole, the patients appeared to be highly accurate at estimating BG (r = .93, P less than .0001).(ABSTRACT TRUNCATED AT 250 WORDS)
An interatrial shunt (IAS) was developed and tested to balance a volumetrically coupled electrohydraulic total artificial heart (EHTAH). The IAS diameter was determined theoretically with the equation: [formula: see text] where D = orifice diameter, delta P = pressure drop across the orifice, rho = fluid density, Q = volume flow through the orifice, and C = empiric constant. The calculated orifice diameter was 2.9-5.3 mm to keep a 3-5 mmHg pressure difference between left and right atria, with 0.42-1.05 L/min of expected flow through the IAS. Three different sizes (3.4, 5.4, and 5.5 mm) of IAS were implanted and tested in four calves. The in vivo left-right pressure difference ranged from 3 to 8 mmHg, with 0.57-1.38 L/min of theoretically calculated flow through the IAS. At autopsy, none of the IAS showed macroscopic thrombus formation.
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