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Boris D Lushniak

Publications and source records attributed to Boris D Lushniak.

3 recordsLinked to original sources

The importance of occupational skin diseases in the United States.

Occupational skin diseases and disorders (OSDs) are the most commonly reported non-trauma-related (acute or cumulative) category of occupational illnesses in the United States. This factor, along with their potential chronicity, their effect on an individual's vocational and avocational activities, and the fact that they are preventable, point out the public health importance of OSDs. It can be difficult to obtain accurate epidemiological data for OSDs in the US, and all sources have their limitations. OSD cases that result in days away from work are important categories to study, since days away from work may be used as an indicator of the severity of a case. Descriptive epidemiology may be used to provide further information on these "more severe" cases, to determine, for example, high-risk industries, occupations, and exposures, and then to use this information to target the high-risk, "more severe" cases for prevention strategies. The goal of the US Public Health Service for the year 2010, as established in its "Healthy People 2010: National Health Promotion and Disease Prevention Objectives", is to reduce national OSDs to an incidence of no more than 46 per 100,000 full-time workers. Both irritant and allergic contact dermatitis are considered to be priority research areas as outlined in the National Occupational Research Agenda introduced in 1996 by the National Institute for Occupational Safety and Health. Increased knowledge and awareness of occupational skin diseases will assist in the achievement of the national public health goals.

Absenteeism↗

Evaluation of self-reported skin problems among workers exposed to toluene diisocyanate (TDI) at a foam manufacturing facility.

Toluene diisocyanate, or TDI (CAS 584-84-9) is a well-known asthmagen and respiratory irritant. TDI is also known for its ability to irritate the skin and mucous membranes. To further investigate the dermal effects of TDI, NIOSH investigators conducted a cross-sectional study at a flexible foam manufacturing plant. A total of 114 workers participated in the study. Participants completed a medical questionnaire, provided blood for antibody testing to TDI and other allergens, and a subset of participants reporting skin symptoms underwent skin patch testing to a standard diisocyanate panel. Production line workers were more than twice as likely to report skin problems as those working in nonproduction areas (PRR = 2.66; 95% CI = 1.14-16.32; P = 0.02). Age, gender and duration of employment at the plant were comparable among participants working in production and nonproduction areas. Of the 100 participants who provided blood samples for antibody testing, specific IgG antibody to TDI was detected in two individuals, and none of the samples demonstrated specific IgE antibody to TDI. Of the 26 workers who underwent skin patch testing, none developed reactions to the diisocyanate allergens. These results suggest that the skin symptoms among study participants represent an irritant rather than an immunologic reaction to TDI, or to an unidentified allergen present in the foam.

Adult↗