Biomedical subjects

Boqin Sun

Publications and source records attributed to Boqin Sun.

5 recordsLinked to original sources

PubMed2005

A global inversion method for multi-dimensional NMR logging.

We describe a general global inversion methodology of multi-dimensional NMR logging for pore fluid typing and quantification in petroleum exploration. Although higher dimensions are theoretically possible, for practical reasons, we limit our discussion of proton density distributions as a function of two (2D) or three (3D) independent variables. The 2D can be diffusion coefficient and T(2) relaxation time (D-T(2)), and the 3D can be diffusion coefficient, T(2), and T(1) relaxation times (D-T(2)-T(1)) of the saturating fluids in rocks. Using the contrast between the diffusion coefficients of fluids (oil and water), the oil and water phases within the rocks can be clearly identified. This 2D or 3D proton density distribution function can be obtained from either two-window or regular type multiple CPMG echo trains encoded with diffusion, T(1), and T(2) relaxation by varying echo spacing and wait time. From this 2D/3D proton density distribution function, not only the saturations of water and oil can be determined, the viscosity of the oil and the gas-oil ratio can also be estimated based on a previously experimentally determined D-T(2) relationship.

Journal Article↗

PubMed2005

Two-dimensional nuclear magnetic resonance petrophysics.

Two-dimensional nuclear magnetic resonance (2D NMR) opens a wide area for exploration in petrophysics and has significant impact to petroleum logging technology. When there are multiple fluids with different diffusion coefficients saturated in a porous medium, this information can be extracted and clearly delineated from CPMG measurements of such a system either using regular pulsing sequences or modified two window sequences. The 2D NMR plot with independent variables of T2 relaxation time and diffusion coefficient allows clear separation of oil and water signals in the rocks. This 2D concept can be extended to general studies of fluid-saturated porous media involving other combinations of two or more independent variables, such as chemical shift and T1/T2 relaxation time (reflecting pore size), proton population and diffusion contrast, etc.

Magnetic Resonance Spectroscopy↗

PubMed2004

Methods and limitations of NMR data inversion for fluid typing.

We introduce two NMR inversion methods within the framework of 1D NMR to extract fluid saturations by varying echo spacing and wait time. The first method connects the T2 distribution of each fluid with the overall apparent T2 distribution using a shift matrix. Each fluid's saturation and T2 distribution are extracted by minimizing the difference between the model T2 distributions and measured apparent T2 distributions. The second method relates a model T2 distribution of each fluid with CPMG echo trains using a global evolution matrix that governs the evolution of magnetization under T1, T2 relaxation, and diffusion. These methods will be useful whenever data are not sufficient for 2D NMR inversion. They are also much faster than 2D for fluid typing. We also point out an inherent limitation associated with NMR inversion methods for fluid typing. Whenever there is singularity in the inversion matrix caused by similar behavior of model function for different fluids, most inversion algorithms remove the solution space associated with the singularity and choose a solution vector of the minimum length. This results in equal proportions of different fluids in the final answer. If prior knowledge such as saturation or T2 shape of the oil is available, there are several methods to tailor the solution to our desired outcome. However, if there is no prior knowledge available, such ambiguity always exists irregardless of the inversion schemes.

Journal Article↗

PubMed2003

Rotational resonance NMR: separation of dipolar coupling and zero quantum relaxation.

The solid state NMR technique of rotational resonance (R2) has been used extensively to measure distances approaching 5-6 A between 13C nuclei in a variety of compounds including amyloidogenic peptides and membrane proteins. The accuracy of the distance information extracted from the time-dependent spin dynamics at R2 is often limited by the accuracy with which the relevant zero-quantum lineshape parameters are estimated. Here we demonstrate that measurement of spinning frequency dependent magnetization exchange dynamics provides data from which both distance and zero-quantum relaxation parameters can be extracted independently. In addition to providing more accurate distance information, this technique allows examination of the zero-quantum lineshape, which can indicate the presence of correlated relaxation or chemical shift distributions between dipolar-coupled sites. With this approach we have separated the contribution of dipolar couplings and zero quantum relaxation to R2 exchange curves. Thus, we have significantly improved the accuracy of the measurement of the intramolecular, internuclear distances between a pair of 13C's in two model compounds (N-acetyl-D,L-valine and glycylglycine.HCl) that lie in the distance range 4.6-4.7 A.

Carbon Isotopes↗

PubMed2002

Probing the internal field gradients of porous media.

We devise a modified Carr-Purcell-Meiboom-Gill pulse sequence that allows us to probe the apparent internal field gradient distribution of a fluid-saturated porous medium as a function of the pore size. This distribution is displayed as a two-dimensional map with one axis being the field gradient, another axis being the T2 relaxation time reflecting different pore sizes, and the vertical amplitudes being proportional to the proton population. Such a scheme of two-dimensional representation for fluid-saturated porous media can also be used for the identification of pore fluids using the contrast of their diffusion coefficients.

Journal Article↗