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Biomedical subjects

Bonita Falkner

Publications and source records attributed to Bonita Falkner.

22 records · Page 2Linked to original sources

Obesity, smoking, and multiple cardiovascular risk factors in young adult African Americans.

OBJECTIVES: To examine the associations between the combination of obesity and tobacco use and total cardiovascular risk score in young adult African Americans. DESIGN: A cross-sectional study of 323 African-American men (N = 117) and women (N = 206) aged 20-46 years. METHODS: Age, height, weight, and data on smoking behavior were obtained, as well as measurements of blood pressure, serum lipids, and measurements from an oral glucose tolerance test (OGTT). A cardiovascular risk score was calculated from the above data. RESULTS: Fasting insulin, fasting blood glucose, and blood glucose at 120 minutes of OGTT were significantly higher in obese (body mass index [BMI] > or = 30 kg/m2) men. Obese men also had significantly higher LDL cholesterol, lower HDL cholesterol and higher total risk scores. Obese women had significantly higher blood pressure, higher fasting insulin, lower LDL cholesterol, and higher total risk scores. Among the members of this cohort, 65% of men and 79% of women were obese and/or smoked. Of those who were obese and/or smoked, 68% of the men and 82% of the women had at least one other cardiovascular risk factor. CONCLUSIONS: The modifiable risk factors of obesity and smoking were present in a large majority of these young adult African Americans in association with other cardiovascular risk factors.

Adult↗

Evaluation of Hypertension in Older Children and Adolescents.

Hypertension occurs in children as well as adults. Unlike adults, the rates of hypertension in childhood are lower and the methods of diagnosis and evaluation vary somewhat. In the following review on the diagnosis and management of hypertension in older children, three typical cases will be discussed. Key issues in the methods and criteria used in the diagnosis of hypertension will be described. The secondary causes of hypertension in the young, the characteristics of essential hypertension, and the management of hypertension in the young will also be discussed in the context of typical cases. (c)1999 by Le Jacq Communications, Inc.

Journal Article↗

The association between hypertension and other cardiovascular risk factors in young adult African Americans.

Hypertension is a major cause of cardiovascular disease in African Americans. The excess morbidity and mortality due to cardiovascular disease in African Americans compared to Caucasians is not well explained. The purpose of this study was to examine the association between hypertension and other cardiovascular risk factors in young adult African Americans. A risk factor scoring system was developed, based on national guidelines for obesity, smoking, cholesterol levels, glucose tolerance, and blood pressure. Data from a previously studied cohort of 206 women and 117 men were analyzed for the association of hypertension with other risk factors. Among women, risk factor intensification is due to impaired glucose tolerance and obesity. Among men, intensification appears to be related to all major risk factor categories. These findings indicate that among hypertensive African Americans there is an amplification of other risk factors. The data also support the clinical management of multiple risk factors as well as the achievement of blood pressure control.

Adult↗