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Biomedical subjects

Bogale Worku

Publications and source records attributed to Bogale Worku.

5 recordsLinked to original sources

Kangaroo mother care: a randomized controlled trial on effectiveness of early kangaroo mother care for the low birthweight infants in Addis Ababa, Ethiopia.

A randomized controlled trial was conducted over a 1-year period (November 2001-November 2002) in Addis Ababa to study the effectiveness of early Kangaroo mother care before stabilization of low birthweight infants as compared with the conventional method of care. There were 259 babies weighing less than 2000 g during the study period and a total of 123 (47.5 per cent) low birthweight infants were included in to the study. Sixty-two infants were enrolled as Kangaroo Mother Care (KMC) and the remaining 61 were Conventional Method of Care (CMC) cases. The demographic and socioeconomic characteristics for both groups were comparable. The mean age at the time of enrollment was 10 and 9.8 h for KMC and CMC, respectively (p>0.05 with 95 per cent confidence interval). The mean birthweight was 1514.8 g (range 1000-1900 g) for KMC and 1471.8 g (range 930-1900 g) for CMC (p>0.05 with 95 per cent CI) and the mean gestational age was 32.42 and 31.59 weeks for KMC and CMC cases, respectively. Fifty-eight per cent of KMC and 52 per cent of CMC cases were on i.v. fluid. Twenty-one of 62 (34 per cent) of KMC and 23/61 (37 per cent) of CMC babies were on oxygen through nasopharyngeal catheter. The mean age at exit from the study was 4.6 days for KMC and 5.4 days for CMC. Ninety-one per cent and 88 per cent of babies in KMC and CMC were discharged from the study in the first 7 days of life, respectively. The study showed that 14/62 (22.5 per cent) of KMC vs. 24/63 (38 per cent) CMC babies died during the study (p<0.05 and CI of 95 per cent.) The majority of deaths occurred during the first 12 h of life. Survival for the preterm low birthweight infants was remarkably better for the early kangaroo mother care group than the babies in the conventional method of care in the first 12 h and there after. More than 95 per cent of mothers reported that they were happy to care for their low birthweight babies using the early Kangaroo mother method. It was recommended to study the feasibility and effectiveness of Kangaroo mother care at the community level.

Ethiopia↗

Kangaroo Mother Care: 25 years after.

UNLABELLED: The components of the Kangaroo Mother Care (KMC) intervention, their rational bases, and their current uses in low-, middle-, and high-income countries are described. KMC was started in 1978 in Bogotá (Colombia) in response to overcrowding and insufficient resources in neonatal intensive care units associated with high morbidity and mortality among low-birthweight infants. The intervention consists of continuous skin-to-skin contact between the mother and the infant, exclusive breastfeeding, and early home discharge in the kangaroo position. In studies of the physiological effects of KMC, the results for most variables were within clinically acceptable ranges or the same as those for premature infants under other forms of care. Body temperature and weight gain are significantly increased, and a meta-analysis showed that the kangaroo position increases the uptake and duration of breastfeeding. Investigations of the behavioral effects of KMC show rapid quiescence. The psychosocial effects of KMC include reduced stress, enhancement of mother-infant bonding, and positive effects on the family environment and the infant's cognitive development. CONCLUSION: Past and current research has clarified some of the rational bases of KMC and has provided evidence for its effectiveness and safety, although more research is needed to clearly define the effectiveness of the various components of the intervention in different settings and for different therapeutic goals.

Adult↗

Occurrence of intra-ventricular hemorrhage among preterm infants admitted in Tikur Anbessa Hospital.

All preterm babies admitted to the neonatal unit of Tikur Anbessa Hospital (TAH) Addis Ababa from November 2000 to November 2001 were followed until discharge or death. There were 298 babies with birth weight of less than 2000 gm and Gestational age of less than 36 weeks. 56 babies died (56/298 = 28%) and consent was obtained to perform autopsy examination on all of them. The mean Gestational age was 31 weeks with the range of 26-35 and the mean birth weight was 1377 grams with the range of 780-1900 grams. Intra ventricular Hemorrhage (IVH) was seen in 18 (18/56 = 32%) preterm infants on autopsy examination. IVH occurred on 36.4% of cases in preterm infants with birth weight of <1500 gm and gestational age of <32 weeks. 16/18 (88.8%) of babies who had IVH were less than 1500 grams. All babies with IVH were in respiratory distress and required resuscitation. Recommendations are made to improve delivery services and neonatal intensive care unit services to reduce incidence of IVH in preterm babies.

Birth Weight↗

Cyclopia.

A deformity consisting of a single orbital fossa with absent globes with proboscis like structure on forehead is described in a 1200 gram female neonate who died immediately after birth. This neonate was born to a 35 years old Para VIII mother at term. Observations from clinical and post mortem examination are presented and literature review made. Because of its rare occurrence and tentative evidence for both genetic and environmental etiologies, reporting of cases of Cyclopia is encouraged.

Abnormalities, Multiple↗

Pattern of hypothyroid disorders in Ethio-Swedish Children's Hospital (ESCH).

All children with thyroid disorder attending the endocrinology clinic of the Ethio-Swedish Children's Hospital (ESCH), Addis Ababa in 1996 were included in this study. One hundred twenty six new patients from all over the country were referred to the clinic for thyroid disorder and 31 patients (24%) were found to have hypothyroidism. Seventeen (13%) had congenital hypothyroidism while the rest 14(11.5%) were categorised to have juvenile hypothyroidism. Thyroid dysgenesis is the commonest cause of permanent hypothyroidism. Mental retardation was the accompanied manifestation in all the cases with thyroid agenesis except in two children. Mental retardation being the commonest permanent sequelae in aplastic hypothyroidism is of utmost concern and its prevention is desirable, therefore high index of clinical suspicion with a close observation for early feature of congenital hypothyroidism is warranted for early intervention and in the future nation wide screening for hypothyroidism is recommended.

Child↗